research Fibroblast Lineage Switching as the Developmental Origin of Scarring and Target for Regenerative Healing
Reprogramming adult fibroblasts may enable scar-free healing.
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research Defining Skin Fibroblastic Cell Types Beyond CD90
The conclusion is that CD90 is not a specific marker for fibroblast subtypes and better methods are needed to identify them.
research Fibroblast Lineage Switching as the Developmental Origin of Scarring and Target for Regenerating Healing
Mimicking fetal wound environments may enable scarless healing in adults.
research Spatial and Single-Cell Transcriptional Profiling Identifies Functionally Distinct Human Dermal Fibroblast Subpopulations
Researchers found four distinct fibroblast types in human skin, which could help in treating wounds and fibrotic diseases.
research Cultured human skin fibroblasts: a model for the study of androgen action
research Distinct fibroblast lineages determine dermal architecture in skin development and repair
Two fibroblast types shape skin structure and repair differently.
research Macrophages and fibroblasts during inflammation and tissue repair in models of organ regeneration
Macrophages and fibroblasts help repair organs after injury, affecting whether they regenerate or scar.
research Diversity of Fibroblasts and Their Roles in Wound Healing
Different fibroblast types play key roles in wound healing and could lead to better treatments.
research Dermal fibroblasts: the terminology, heterogeneity of subpopulations and common properties
Dermal fibroblasts have at least three distinct types, each with unique roles in skin structure and hair development.
research Single-cell analysis reveals fibroblast heterogeneity and myeloid-derived adipocyte progenitors in murine skin wounds
The research found that different types of fibroblasts are involved in wound healing and that some blood cells can turn into fat cells during this process.
research Human Dermal Fibroblasts Demonstrate Positive Immunostaining for Neuron- and Glia- Specific Proteins
Fibroblasts can be mistaken for neural cells, so functional validation is needed.
research Fibroblasts become fat to reduce scarring
Turning scar-forming cells into fat cells can reduce scarring.
research Single‐cell transcriptomic analysis of small and large wounds reveals the distinct spatial organization of regenerative fibroblasts
Different types of skin cells are organized in a special way in large wounds to help with healing and hair growth.
research Intradermal adipocytes mediate fibroblast recruitment during skin wound healing
Fat cells help recruit healing cells and build skin structure during wound healing.
research Differentiation capacity of stromal fibroblast-like cells from human bone marrow, adipose tissue, hair follicle dermal papilla and derma
research Alteration of Skin Properties with Autologous Dermal Fibroblasts
Using your own skin cells can help repair aging skin and promote hair growth.
research Distinct Fibroblast Lineages Give Rise to NG2+ Pericyte Populations in Mouse Skin Development and Repair
Ng2+ perivascular cells in mouse skin come from specific fibroblast types and help in tissue repair.
research Fibroproliferative genes are preferentially expressed in central centrifugal cicatricial alopecia
Genes linked to fibrosis are more active in people with central centrifugal cicatricial alopecia.
research Autologous Cell Therapy
Autologous cell therapy can reduce facial wrinkles effectively.
research 564 Subpopulations of dermal fibroblasts produce distinct extracellular matrices
Different types of skin cells create unique support structures that can affect skin cell growth and could help in skin repair.
research 973 Dipeptidyl-peptidase 4 (DPP4)-positive fibroblasts are responsible for secretion of pro-fibrotic matrix proteins in the human skin
DPP4-positive fibroblasts play a major role in producing proteins that lead to skin fibrosis.
research Comparison of hair dermal cells and skin fibroblasts in a collagen sponge for use in wound repair
research Subpopulations of dermal skin fibroblasts secrete distinct extracellular matrix: implications for using skin substitutes in the clinic
Different skin cells produce unique materials, which can improve skin substitutes for healing.
research Distinct Regulatory Programs Control the Latent Regenerative Potential of Dermal Fibroblasts during Wound Healing
Dermal fibroblasts have adjustable roles in wound healing, with specific cells promoting regeneration or scar formation.
research Adipocytic Progenitor Cells Give Rise to Pathogenic Myofibroblasts: Adipocyte-to-Mesenchymal Transition and Its Emerging Role in Fibrosis in Multiple Organs
Targeting adipocyte-to-mesenchymal transition could help treat fibrosis.
research Fibroblast depletion reveals mammalian epithelial resilience across neonatal and adult stages
The skin can still regenerate and function well even with fewer fibroblasts.
research Fibroblasts and endothelial cells interplay drives hypertrophic scar formation: Insights from in vitro and in vivo models
Fibroblast and endothelial cell interactions are crucial in forming hypertrophic scars.
research 線維芽細胞凝集塊形成による幹細胞形成機構の解明
Fibroblast spheres can form stem cells, but marker distribution needs more study.
research Single-cell analysis of murine fibroblasts identifies neonatal to adult switching that regulates cardiomyocyte maturation
Adult fibroblasts help heart cells mature and improve heart function.
research 1390 Lineage-committed fibroblast populations are more efficient at regenerating hair follicles in chamber grafting assays when compared to undifferentiated embryonic fibroblasts
Differentiated fibroblasts regenerate hair follicles better than undifferentiated ones.