research Autoimmunity: Alopecia Areata
Alopecia areata is an autoimmune disease causing hair loss, treatable with immune-modulating drugs, and linked to genetics.
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research Measuring Patient Quality of Life Following Treatment for Alopecia
Alopecia treatments improve life quality but side effects can lessen this benefit; better use of quality of life measures is needed.
research What is behind the ‘swarm of bees’ in alopecia areata
Alopecia areata is caused by immune system issues, and JAK inhibitors might help treat it.
research Biomarkers in alopecia Areata: A systematic review and meta-analysis.
High levels of IL6 and CRP, and low levels of vitamin D, might be indicators of alopecia areata.
research Increased proliferation of epidermal gamma delta T cells and expression of the transmembrane protein, BST2, in Alopecia areata
BST2 protein and certain T cells increase in early alopecia areata.
research [Significance of HLA-DR+ T cells and natural killer (NK) cells in the peripheral blood lymphocytes of alopecia areata (AA)].
Severe alopecia areata involves higher levels of certain immune cells, which can be normalized with betamethasone.
research Content validity of five single‐item instruments in adolescents with alopecia areata
The instruments are valid but don't fully capture the emotional impact on adolescents with alopecia areata.
research Use of oral Janus kinase inhibitors for the treatment of severe alopecia areata: narrative review and real-world experience
Janus kinase inhibitors help some people with severe alopecia areata regrow hair, but not everyone responds, and relapses can happen.
research Exploration of Potential Secondary Plant Metabolites for the Treatment of Alopecia Areata
Secondary plant metabolites may offer a safer treatment for alopecia areata.
research Frontal Fibrosing Alopecia and the Role of Cosmeceuticals in Its Pathogenesis
Cosmeceuticals like sunscreens may trigger frontal fibrosing alopecia, but more research is needed.
research 801 TEC family kinase inhibitors as a novel class of therapeutics in alopecia areata
ITK inhibitors may effectively treat alopecia areata.
research 253 Frontal fibrosing alopecia: clinical and therapeutic considerations - case series
Early treatment and multidisciplinary care are key to managing Frontal Fibrosing Alopecia and preventing further hair loss.
research Which is the ideal JAK inhibitor for alopecia areata – Baricitinib, tofacitinib, ritlecitinib or ifidancitinib - Revisiting the immunomechanisms of the JAK pathway
No single ideal JAK inhibitor for alopecia areata has been determined; JAK3 inhibitors may be promising with fewer side effects.
research 034 Characterization of novel TMEM173 mutation causing a lupus- and SAVI-like phenotype, modified by polymorphisms in TMEM173 and IFIH1
A new mutation in the STING protein causes a disease with lupus-like symptoms and responds well to a specific inhibitor treatment.
research Maintenance of Hair Follicle Immune Privilege Is Linked to Prevention of NK Cell Attack
Hair follicles prevent NK cell attacks to avoid hair loss.
research Applications of Antioxidant Nanoparticles in Immune-Mediated Inflammatory Diseases
Antioxidant nanoparticles show promise for treating inflammatory diseases but need more research for safe and effective use.
research Vitiligo and alopecia areata: apples and oranges?
Vitiligo and alopecia areata may have similar causes despite their differences.
research Immune Privilege Collapse and Alopecia Development: Is Stress a Factor
Stress may trigger hair loss by affecting immune protection in hair follicles.
research Cicatricial (Scarring) Alopecias
Scarring alopecias are complex hair loss disorders that require early treatment to prevent permanent hair loss.
research Janus kinase inhibitors for alopecia areata: A narrative review
Janus kinase inhibitors can regrow hair in alopecia areata but may cause side effects and hair loss may return if treatment stops.
research Folate receptor β performs an immune checkpoint function in activated macrophages
Folate receptor β helps suppress the immune system in macrophages and affects cancer growth and hair health.
research Impending central retinal vein occlusion and granulomatous uveitis in a patient with Satoyoshi syndrome
Satoyoshi syndrome can cause eye problems like uveitis and retinal vein issues.
research Pyroptosis in Alopecia Areata: Synthesizing Emerging Hypotheses and Charting a Path to New Therapies
Targeting pyroptosis may offer new treatments for alopecia areata, but more research is needed.
research ALOPECIA AREATA PROFILING SHOWS LNCRNAS REGULATE THE SUPPRESSED EXPRESSION OF KERATIN.
Certain RNAs may help diagnose alopecia areata by affecting keratin genes.
research Alopecia areata in childhood, clinical manifestations and therapeutic approaches
Alopecia areata in children causes hair loss and needs a personalized treatment plan with medical and emotional support.
research The Effect of Botulinum Toxin on Hair Follicle Cell Regeneration Under Continuous Stress Conditions: a Pilot Animal Study
Botulinum toxin may help reduce stress-related hair loss.
research Index of Suspicion
The document says that hookworms are treated with mebendazole and stress-related hair loss usually gets better in 6 months, while other hair loss types have specific treatments.
research Akkermansia muciniphila promotes testosterone‐mediated hair growth inhibition in mice
Akkermansia muciniphila may help prevent testosterone-related hair loss.
research Deficient anterior pituitary with common variable immune deficiency (DAVID syndrome): a new case and literature reports
DAVID syndrome is a condition with immune system and hormone deficiencies, needing early diagnosis to avoid serious complications.
research The alopecia areata phenotype is induced by the water avoidance stress test in cchcr1-deficient mice
Stress can cause a type of hair loss in mice lacking the CCHCR1 gene.