9 citations
,
October 2017 in “Frontiers in plant science” The peach gene CTG134 helps control the interaction between auxin and ethylene, which could lead to new agricultural chemicals.
January 2023 in “Methods in molecular biology” ROP GTPase helps control the growth of pollen tubes and root hairs by managing cell structure and movement.
100 citations
,
December 2002 in “Journal of biological chemistry/The Journal of biological chemistry” Researchers mapped and categorized specific keratin-associated protein genes on human chromosome 21q22.1.
34 citations
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January 2004 in “Genomics” A cluster of 21 keratin-associated protein genes important for hair growth was found on human chromosome 21.
TLR2 is crucial for hair growth and regeneration, and boosting it can help prevent hair loss.
May 2023 in “The Journal of Immunology” BST2 is a key marker for hair loss disease alopecia areata.
29 citations
,
December 2016 in “The EMBO Journal” Gata6 is important for protecting hair growth cells from DNA damage and keeping normal hair growth.
2 citations
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April 2017 in “Molecular Medicine Reports” Blocking autophagy increases survival of inner ear hair cells exposed to gentamicin.
65 citations
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June 2003 in “EMBO journal” Noggin overexpression delays eyelid opening by affecting cell death and skin cell development.
October 2005 in “Nature reviews. Molecular cell biology (Print)” Hairless protein is key for hair growth, cell differences cause gene expression variation, and the N-end rule pathway senses nitric oxide for protein breakdown.
1 citations
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January 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Weak cell junctions disrupt hair follicle stem cell rest.
June 2025 in “Proceedings of the National Academy of Sciences” A PIK3CA mutation in Schwann cells causes severe nerve damage and increased glycolysis, but early treatment can help.
13 citations
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September 2019 in “EBioMedicine” sPLA2-IIA increases growth in hair follicle stem cells and cancer cells, suggesting it could be targeted for hair growth and cancer treatment.
January 2025 in “eScholarship@McGill (McGill)”
March 2026 in “bioRxiv (Cold Spring Harbor Laboratory)” Spiny mice have a unique skin structure that helps them heal and regenerate quickly.
10 citations
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October 2018 in “Journal of molecular and cellular cardiology/Journal of Molecular and Cellular Cardiology” The gene NM_026333 slows down aging by affecting the NCX1 pathway and could be targeted for anti-aging treatments.
November 2022 in “Journal of Investigative Dermatology” Low oxygen levels affect the behavior of certain proteins in human skin cells.
211 citations
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April 2018 in “Cold Spring Harbor Perspectives in Biology” Keratins are crucial for cell structure, growth, and disease risk.
5 citations
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August 2012 in “Experimental Dermatology” Artemis phosphorylation at Ser516 may help regulate skin and hair structures.
990 citations
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October 1999 in “Development” Activated LEF/TCF complexes are crucial for hair development and cycling.
January 2025 in “BMC Genomics” Key genes and RNA networks regulate hair growth and follicle density in Rex rabbits.
12 citations
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December 2003 in “Gene” The ovine Hoxc-13 gene is crucial for hair formation and may have other skin functions.
2 citations
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October 2023 in “Philosophical Transactions of the Royal Society B Biological Sciences” Different PADI isoforms help cells develop diverse functions.
3 citations
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October 2024 in “International Journal of Molecular Sciences” Xenopus laevis tadpoles can regenerate complex tail structures, offering insights for regenerative medicine.
122 citations
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July 1994 in “Journal of Investigative Dermatology” July 2002 in “Science s STKE” Modified β-catenin causes different effects in hair and skin cells, leading to cysts or tumors.
June 2010 in “Chinese Journal of Dermatology” A new gene mutation is linked to monilethrix in the studied family.
204 citations
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October 1999 in “EMBO journal” Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.
95 citations
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March 2009 in “Differentiation” Gene expression in wool follicles changes with growth cycles, offering insights into wool and human hair growth.
May 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” EAAT4 decreases with age, harming skin function and calcium balance.