research S100A8 induces cyclophosphamide-induced alopecia via NCF2/NOX2-mediated ferroptosis
Blocking S100A8 can reduce chemotherapy-induced hair loss.
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690-720 / 1000+ resultsresearch Immortality Reconsidered: Clinical Challenges at the Frontier of Plastic Surgery
Advancements in regenerative science and longevity research can improve healthspans, but must be balanced with ethics and safety.
research Cellular and molecular mechanisms of repair in acute and chronic wound healing
Acute wounds heal well, but chronic wounds struggle due to ongoing inflammation and poor tissue repair.
research Emerging roles of Sox6 in the renal and cardiovascular system
Sox6 is important in heart and kidney health, affecting diseases like diabetes, heart disease, and high blood pressure.
research The role of glucose metabolism in wound healing: an overview
Glucose metabolism is crucial for wound healing but can delay healing in chronic wounds due to increased stress and inflammation.
research Opportunities and challenges of bacterial extracellular vesicles in regenerative medicine
Bacterial extracellular vesicles could revolutionize regenerative medicine but need safety improvements.
research Identification of A p300–SP1–BRD4 Transcriptional Axis as a Key Driver of AR Hyperactivation in Polycystic Ovarian Syndrome
Targeting the p300/AR axis may help treat polycystic ovary syndrome.
research EMT Factors and Metabolic Pathways in Cancer
EMT and metabolic pathways help cancer cells resist treatment and spread.
research ERG induces androgen receptor-mediated regulation of SOX9 in prostate cancer
ERG increases SOX9, promoting prostate cancer growth and invasion.
research Mettl3-catalyzed m 6 A regulates histone modifier and modification expression in self-renewing somatic tissue
Mettl3 is essential for normal tissue development and self-renewal by regulating gene expression.
research Synthesis and biological activity evaluation of new isatin-gallate hybrids as antioxidant and anticancer agents (in vitro) and in silico study as anticancer agents and coronavirus inhibitors
New isatin-gallate hybrids show promise as antioxidants, cancer treatments, and coronavirus inhibitors.
research Decision letter: Loss of Dnmt3a and Dnmt3b does not affect epidermal homeostasis but promotes squamous transformation through PPAR-γ
Loss of Dnmt3a and Dnmt3b increases aggressive skin tumors by affecting PPAR-γ.
research RAGE and Its Ligands in Melanoma
RAGE is a potential target for melanoma treatment, but its effectiveness is uncertain due to variable expression levels.
research Visible-to-Near IR Quantum Dot–Based Hypermulticolor High-Content Screening of Herbal Medicines for the Efficacy Monitoring of Hair Growth Promotion and Hair Loss Inhibition
Some herbal extracts can promote hair growth and prevent hair loss.
research Regeneration Genetics
Understanding tissue regeneration in animals can improve regenerative medicine.
research A Novel In Vivo Active Pemphigus Model Targeting Desmoglein1 and Desmoglein3: A Tool Representing All Pemphigus Variants
New mouse models of Pemphigus show severe symptoms and need better treatments.
research Squaric Acid Dibutylester Promotes Innate Immune-Driven Hair Growth with CD206+ Macrophage Accumulation in the Dermis
Squaric acid dibutylester promotes hair growth by activating immune cells, especially macrophages.
research Activated Polyamine Catabolism Depletes Acetyl-CoA Pools and Suppresses Prostate Tumor Growth in TRAMP Mice
Overexpressing SSAT enzyme reduces prostate tumor growth in mice.
research Hydrogel-Based Skin Regeneration
Hydrogels show promise for improving skin wound healing.
research Leveraging nature’s nanocarriers: Translating insights from extracellular vesicles to biomimetic synthetic vesicles for biomedical applications
Biomimetic synthetic vesicles could improve precision medicine by combining natural and synthetic benefits.
research Human epidermal neural crest stem cells as a source of Schwann cells
Human Schwann cells can be quickly made from hair follicle stem cells for nerve repair.
research Emerging Roles for Ion Channels in Ovarian Cancer: Pathomechanisms and Pharmacological Treatment
Ion channels play a key role in ovarian cancer growth and treatment resistance.
research Endocrine effects of long-term calcineurin inhibitor use in solid organ transplant recipients
Long-term use of calcineurin inhibitors in transplant patients can cause hormone issues that can be managed with proper care.
research Spatiotemporal regulation of acute wound healing by the NLRP3 inflammasome: dual roles in macrophage-fibroblast chemotaxis and phenotype during wound repair
NLRP3 helps control inflammation and repair in wound healing, making it a potential target for treatment.
research Nitrogen‐Boosted H 2 O 2 Production of Arginine‐Polyphenol Nanozyme Drives Oxidative Eustress for Hair Regeneration
A new nanozyme using EGCG and L-arginine boosts hair growth by safely increasing beneficial oxidative stress.
research Orchestration of Mesenchymal Stem/Stromal Cells and Inflammation During Wound Healing
Mesenchymal Stem/Stromal Cells (MSCs) help in wound healing and tissue regeneration, but can also contribute to tumor growth. They show promise in treating chronic wounds and certain burns, but their full healing mechanisms and potential challenges need further exploration.
research CD44 signaling in skin wound healing and regeneration
CD44 signaling can help heal wounds without scars.
research Hypotrichosis with juvenile macular dystrophy: a case report with molecular study
A rare genetic disorder causes sparse hair and vision loss due to a CDH3 gene mutation.
research Natural killer cells in atopic and autoimmune diseases of the skin
NK cells play a role in skin diseases like eczema and psoriasis.
research Research Progress on the Immunomodulatory Effects by Dang Gui (Radix Angelica sinensis) and Its Active Chemical Components
Dang Gui may help treat immune-related diseases by boosting and regulating the immune system.