research Pathophysiology of the Behçet's Disease
Behçet's Disease may be caused by genetic and environmental factors leading to abnormal immune responses, and stress management and new treatments could improve patient outcomes.
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930-960 / 1000+ results research Multifunctional antibacterial bioactive nanoglass hydrogel for normal and MRSA infected wound repair
The hydrogel speeds up healing of normal and MRSA-infected wounds.
research Low serum biotin in Japanese children fed with hydrolysate formula
Japanese infants fed hydrolysate formula may have low biotin levels.
research EP-2271: The role of mitochondria in the non-targeted effect of ionizing radiation
Mitochondria may influence how cells respond to radiation, affecting nearby non-irradiated cells.
research Real-time iTRAQ-based proteome profiling revealed the central metabolism involved in nitrogen starvation induced lipid accumulation in microalgae
Nitrogen starvation in microalgae increases lipid production, making it a potential biofuel source.
research Μελέτη της έκφρασης των δεικτών πολυδυναμικότητας στις ιδιοπαθείς φλεγμονώδεις νόσους του εντέρου
OCT4B1 and SOX-2 levels are higher in Crohn's and ulcerative colitis patients, possibly aiding tissue repair.
research Effect of Vitamin D on the Expression of Inflammatory Biomarkers in Cultured Sebocytes Treated withPropionibacterium acnesor Ultraviolet B Irradiation
Vitamin D may help reduce inflammation in acne.
research Topical application of Bifidobacterium‐fermented soy milk extract containing genistein and daidzein improves rheological and physiological properties of skin
Applying a special soy milk extract on skin can make it more elastic and hydrated.
research Synthesis of Analogues of Cercidin, an Antimicrobial Compound of Cercidiphyllum japonicum : Glycosylation of Methyl Gallate with Ulosyl Bromides
Researchers created 10 new compounds similar to cercidin, which could lead to new antibiotics.
research The resistance mechanisms of bacteria against ciprofloxacin and new approaches for enhancing the efficacy of this antibiotic
Combining ciprofloxacin with other treatments may improve its effectiveness against resistant bacteria.
research Alkyl shikimates promote proliferation of human dermal fibroblasts and exhibit structure–activity relationships
The study investigated the effects of alkyl shikimates (SAEs) on human dermal fibroblast proliferation, revealing that SAEs with shorter alkyl chains (CH3, C2H5, C3H7) increased proliferation by 30-50% at 5.5 mM, while those with longer chains (C4H9, C5H11) showed low proliferation or cytotoxicity. The proliferation rates correlated with the hydrophobicity and membrane permeability of SAEs, suggesting that membrane-permeable SAEs form complexes with carboxylesterase in fibroblasts, leading to intracellular hydrolysis into shikimic acid (SA) and alcohols (ALs), with SA promoting proliferation. The study found no significant differences in binding energy between CES and SAEs, indicating that the differences in proliferation are likely due to the intracellular regeneration of SA and the varying toxicity of ALs based on alkyl chain length.
research The targeted overexpression of a Claudin mutant in the epidermis of transgenic mice elicits striking epidermal and hair follicle abnormalities
research The Atypical Itch That Rashes-- Disseminated and Recurrent Infundibulofolliculitis (DRIF) in an Atopic African American Male
Consider DRIF and perform skin biopsies for persistent papular rashes.
research A comparison of the cytotoxic effects of fatty acids on in vitro breast and prostate cell lines
DHA derivatives, especially didocosahexaenoin, effectively kill prostate cancer cells and may offer a safer cancer treatment option.
research DENOUEMENT—CONTINUED FROM P. 661
Tinea faciei should be considered in neonatal vesicular lesions and confirmed with KOH examination and culture.
research Phenytoin‐mediated androgen metabolism in gingival fibroblasts
Levamisole and finasteride can reduce DHT production, potentially preventing phenytoin-induced gum overgrowth.
research FUNGAL DIVERSITY IN Erinaceus roumanicus: CASE REPORTS ON DERMATOPHYTOSIS IN HEDGEHOGS FROM ROMANIA
This study examines 31 cases of dermatophytosis in northern white-breasted hedgehogs (Erinaceus roumanicus) in Romania, highlighting the zoonotic potential and health challenges faced by hedgehogs in urban environments. The affected hedgehogs, admitted to a wildlife rehabilitation center between 2020 and 2024, showed symptoms such as alopecia, scaling, and hyperkeratosis, with 55% in poor body condition and 39% experiencing dehydration or systemic issues. Diagnosis involved microscopic examination, and treatment with itraconazole led to a 77.4% recovery rate. The study underscores the importance of early diagnosis and treatment for successful rehabilitation and highlights the need for awareness of the disease's impact on both animal welfare and public health.
research A Case of Folliculitis Decalvans With Concomitant Acne Keloidalis Nuchae, Androgenic Alopecia, and Profound Postinflammatory Hyperpigmentation
Folliculitis decalvans mainly affects middle-aged African American men and is treated with antibiotics.
research Alterations in the expression of specific epidermal keratin markers in the hairless mouse by the topical application of the tumor promoters 2,3,7,8-tetrachlorodibenzo-p-dioxin and the phorbol ester 12-O-tetradecanoylphorbol-13-acetate
TCDD changes skin cell growth and keratin production in mice.
research Cytotoxic and antioxidant effect of the ethanolic extract of Citrullus colocynthis L. plant fruit
Citrullus colocynthis fruit extract has strong antioxidant and cancer-fighting potential.
research An ethnobotanical review of medicinal plants used for treating hemorrhoids in Thailand
Traditional Thai medicinal plants show promise for treating hemorrhoids.
research Cedrol restricts the growth of colorectal cancer in vitro and in vivo by inducing cell cycle arrest and caspase-dependent apoptotic cell death
Cedrol may be an effective treatment for colorectal cancer.
research Is Propionibacterium acnes associated with hair casts and alopecia?
Propionibacterium acnes might be linked to hair casts and possibly alopecia.
research A subpopulation of itch‐sensing neurons marked by Ret and somatostatin expression
Scientists found a specific group of itch-sensing nerve cells in mice important for feeling itch but not for sensing heat or touch.
research The Human Sebocyte Culture Model Provides New Insights into Development and Management of Seborrhoea and Acne
The human sebocyte culture model has improved understanding of oily skin and acne, and how they can be treated.
research オルニチン・トランスカルバミラーゼ(OTC)欠損(spf・ash)マウスへのOTC遺伝子導入
Introducing the OTC gene improved symptoms in mice with OTC deficiency.
research Promotion of mouse ameloblast proliferation by Lgr5 mediated integrin signaling
CD61 is important for mouse tooth cell growth and works through Lgr5.
research 5-alpha-reductase inhibitors for lower urinary tract symptoms secondary to benign prostatic obstruction
5-alpha-reductase inhibitors help treat urinary symptoms from an enlarged prostate.
research [Effect of biotin on hair roots and sebum excretion in females with diffuse alopecia].
research Induction of ornithine decarboxylase in specific subpopulations of murine epidermal cells following multiple exposures to 12-O-tetradecanoylphorbol-13-acetate, mezerein and ethyl phenylpropriolate
TPA strongly increases ODC activity in certain skin cells, potentially aiding tumor growth.