November 2023 in “Bioorganic Chemistry” Drugs targeting the Androgen Receptor are effective for treating prostate cancer and other androgen-related conditions.
12 citations
,
March 2004 in “Der Urologe” There is no strong evidence that chemopreventive agents effectively prevent prostate cancer.
19 citations
,
March 2010 in “Steroids” Certain progesterone derivatives can inhibit enzymes and reduce androgenic activity, potentially affecting prostate growth.
64 citations
,
October 2018 in “Thérapie” Enriching the French health care database with external data greatly improved its usefulness.
May 2017 in “Psychiatric news” BPH medications may increase the risk of self-harm and depression, especially in the first 18 months.
11 citations
,
December 2002 in “Controlled Clinical Trials” Simple methods using DHT levels effectively assess compliance.
89 citations
,
June 2012 in “Anais Brasileiros de Dermatologia” Actinic keratosis can lead to skin cancer, is more common in fair-skinned people, and can be reduced with sunscreen and treated effectively.
32 citations
,
July 2016 in “PubMed” 5-alpha reductase inhibitors are generally safe but can cause sexual side effects and require patient education on risks.
5 citations
,
November 2015 in “Journal of Enzyme Inhibition and Medicinal Chemistry” Certain derivatives are more effective 5α-reductase type 2 inhibitors than finasteride.
November 2023 in “Clinical, Cosmetic and Investigational Dermatology” A man's rash caused by Finasteride improved after stopping the drug and starting new treatments.
5 citations
,
September 2021 in “Journal of The American Academy of Dermatology” Most men with Frontal fibrosing alopecia also lose facial hair and the condition may be linked to hormone levels and sunscreen use.
27 citations
,
July 2008 in “The Journal of Steroid Biochemistry and Molecular Biology” The new compounds may be more effective and cheaper than current treatments for conditions like baldness.
8 citations
,
October 2024 in “Frontiers in Cell and Developmental Biology” Telocytes help organize male reproductive tissues and their changes can lead to diseases.
August 2025 in “Dermatopathology” Pilomatricomas are often linked to genetic syndromes, especially Apert syndrome, and genetic analysis is crucial for diagnosis.
September 2015 in “Der Internist” Finasteride and minoxidil are effective for hair loss, with potential side effects, and JAK inhibitors show promise for alopecia areata.
Testosterone's health effects are complex and not definitively understood.
September 2024 in “Health of Man” High uric acid can cause health issues, so managing it with lifestyle changes is important.
7 citations
,
December 2022 in “Plants” Guava leaf extract may help treat hair loss and protect cells by blocking certain genes and fighting damaging molecules.
6 citations
,
July 2024 in “Heliyon” Steroid 5α-reductase evolved from protists and diversified in eukaryotes, with specific roles in mammals and plants.
April 2026 in “The Open Biotechnology Journal” Resveratrol shows health benefits but faces challenges in effectiveness and regulation.
February 2026 in “Toxicology Letters” MK-0773 is a moderate inhibitor of the SRD5A2 enzyme.
January 2025 in “Applied Sciences” Sulforaphane from broccoli may help treat certain cancers, hormone issues, and hair loss.
409 citations
,
May 1991 in “Genes & Development” TGF-alpha affects skin thickness, hair growth, and may contribute to psoriasis and papilloma formation.
124 citations
,
January 1993 in “The Prostate” Finasteride effectively inhibits 5α reductase, while plant extracts like Permixon and Bazoton don't show significant results.
March 2005 in “Current Prostate Reports” 1 citations
,
July 2012 in “Prostate Cancer and Prostatic Diseases”
1 citations
,
January 2012 in “International Journal of Trichology” Early hair loss in men and women may indicate a higher risk of heart disease and metabolic problems.
30 citations
,
October 2020 in “Nature Communications” Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.
16 citations
,
September 2014 in “International Journal of Biological Markers” Longer CAG and GGN repeats increase alopecia risk, but no significant link to post-finasteride syndrome found.
14 citations
,
January 2011 in “Journal of analytical & bioanalytical techniques” Created accurate method to measure tamsulosin hydrochloride and finasteride in tablets.