research Hub biomarkers in ultrasound-guided bladder cancer and osteosarcoma: Myosin light chain kinase and caldesmon
Lower levels of MYLK and CALD1 in bladder cancer and osteosarcoma are linked to worse survival rates.
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research Impact of Reporter Type on Signal Detection of Cancer Therapy-Induced Alopecia: A Hypothesis-Generating Study Using the FDA Adverse Event Reporting System
Reporter characteristics affect detection of hair loss from cancer therapy.
research TESTOSTERONE-INDUCED ANDROGENETIC ALOPECIA MICE MODEL: A PRELIMINARY STUDY
A testosterone-induced hair loss model in mice was successfully created for future research and treatment testing.
research Towards Fairer Health Recommendations: finding informative unbiased samples via Word Sense Disambiguation
Fine-tuned BERT models are better than LLMs for detecting bias in medical data.
research Signs of some hematological diseases with the help of monoclonal antibodies LT-1, LT-2, LT-7
Monoclonal antibodies LT-1, LT-2, and LT-7 help diagnose certain blood cancers.
research Endocrinology
The document concludes that inflammation markers can be used in diabetes, vitamin D3 affects immune pathways, hyperthyroidism changes hormone levels, androgen levels help diagnose Adrenocortical Carcinoma, erectile dysfunction is linked to diabetes, hypogonadism is common in HIV-infected males, and hormones can be biomarkers for various conditions.
research Characterization of Rickets Type II Model Rats to Reveal Functions of Vitamin D and Vitamin D Receptor
The research showed that Vitamin D and its receptor are important for healthy bones and normal hair and skin in rats.
research Nanozymes expanding the boundaries of biocatalysis
Nanozymes greatly improve biocatalysis by being stable, efficient, and versatile.
research Synthesis of mimics of steroid A ring as potential enzyme inhibitors
Mimicking the steroid A-ring may help create effective enzyme inhibitors for prostate disease treatment.
research QUALITY ASSESSMENT OF HERBAL MEDICINAL PRODUCTS IN BENIGN PROSTATE HYPERTROPHY: CHEMICAL MARKERS AND FINGERPRINT ANALYSIS
Herbal products for benign prostate hypertrophy need better quality checks to ensure safety and effectiveness.
research Simultaneous determination of seven prohibited substances in cosmetic products by liquid chromatography–tandem mass spectrometry
The method effectively identifies and measures seven banned substances in cosmetics.
research Fast and Noninvasive Hair Test for Preliminary Diagnosis of Mood Disorders
A hair test shows promise for early mood disorder diagnosis.
research Comparison of Alopecia areata in Human and Nonhuman Mammalian Species
The document concludes that certain rats and mice are useful for studying hair loss in humans and testing treatments.
research In Situ Self-Assembling Liver Spheroids with Synthetic Nanoscaffolds for Preclinical Drug Screening Applications
PCL nanoscaffold-based liver spheroids are effective for drug screening and studying liver toxicity.
research Divergent neuroactive steroid responses to stress and ethanol in rat and mouse strains: relevance for human studies
Different rat and mouse strains respond differently to stress and alcohol, which may help us understand similar human mechanisms.
research METHOD DEVELOPMENT AND VALIDATION OF UV-SPECTROPHOTOMETRIC ESTIMATION OF FINASTERIDE IN BULK AND PHARMACEUTICAL DOSAGE FORM
A reliable, cost-effective method was developed for accurately measuring finasteride in medicines.
research Determination of some sex hormones in health supplements by liquid chromatography with tandem mass spectrometry
The method detected sex hormones in some health supplements, with one containing banned testosterone.
research A comprehensive investigation into the molecular mechanism responsible for selective androgen receptor (SARM) tissue-selectivity
SARMs work differently in tissues due to unique interactions and structures.
research Peer Review #3 of "Computational drug repositioning based on side-effects mined from social media (v0.2)"
The study improved and was accepted despite initial concerns about data clarity, methodology, and potential overfitting.
research Comparison of two in vitro models for the analysis of follicular penetration and its prevention by barrier emulsions
Pig ear skin is better than human skin for testing how well barrier creams block allergens from entering hair follicles.
research Adsorptive cathodic stripping determination of minoxidil in pharmaceutical, cream and shampoo products
Researchers developed a sensitive method to measure minoxidil in various products with high accuracy.
research Cortisol determination in hair and faeces from domestic cats and dogs
Hair cortisol can reliably indicate chronic stress in cats and dogs.
research Modeling using discriminant analysis of the possibility of occurrence and features of the course of various forms of urticaria in ukrainian women depending on the features of anthropo-somatotypological indicators
The models accurately predicted urticaria in Ukrainian women but struggled to differentiate between mild and severe cases based on body structure.
research Cyproterone Acetate Quantification in Human Plasma by High-performance Liquid Chromatography Coupled to Atmospheric Pressure Photoionization Tandem Mass Spectrometry
The method accurately measures cyproterone acetate in plasma, showing no significant difference between two formulations.
research Comparative studies of hair shaft components between healthy and diseased donors
Hair analysis can help identify specific minerals and amino acids linked to various diseases.
research BroadAMP-GPT: AI-Driven generation of broad-spectrum antimicrobial peptides for combating multidrug-resistant ESKAPE pathogens
BroadAMP-GPT effectively creates antimicrobial peptides to fight drug-resistant bacteria.
research Hair keratin molecular dynamics models
Molecular dynamics simulations help understand keratin's properties and predict hair's response to treatments.
research Ligand Based 3D-QSAR Study on a Series of Steroidal Human 5α-Reductase Inhibitors
research A Novel 3D Printed Model of Infected Human Hair Follicles to Demonstrate Targeted Delivery of Nanoantibiotics
Nanoencapsulated antibiotics are more effective in treating hair follicle infections than free antibiotics.
research Modelling Human Hair Follicles—Lessons from Animal Models and Beyond
Improving human hair follicle models is crucial for better hair loss treatments.