research Safety of Biological Therapies for Severe Asthma: An Analysis of Suspected Adverse Reactions Reported in the WHO Pharmacovigilance Database
Biologics for severe asthma have known side effects, but some new risks need more study.
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research Chemically Induced Depigmentation of Skin and Hair
Some chemicals can permanently or temporarily remove color from skin and hair, which can be distressing and is not well-regulated in cosmetics.
research Symptom management in inflammatory bowel disease
Effective symptom management in IBD improves quality of life and prevents complications.
research Comparison of Activities Dependent on Glutathione S-Transferase and Cytochrome P-450 IA1 in Cultured Keratinocytes and Reconstructed Epidermal Models
Reconstructed skin models are useful for studying how skin processes certain chemicals.
research Pharmacokinetic study in hairless rat after topical application of finasteride: single and repeated dose
research Liposomes in dermatology today
Liposomes improve drug delivery and reduce skin irritation in dermatology.
research Toxicity of the pharmaceuticals finasteride and melengestrol acetate to benthic invertebrates
Finasteride harms invertebrates' survival and burial ability.
research Multicentric parallel phase II trial of the polo-like kinase 1 inhibitor BI 2536 in patients with advanced head and neck cancer, breast cancer, ovarian cancer, soft tissue sarcoma and melanoma. The first protocol of the European Organization for Research and Treatment of Cancer (EORTC) Network Of Core Institutes (NOCI)
BI 2536 had limited effectiveness against several advanced cancers and caused significant side effects.
research Editorial: Targeted immunological therapies in dermatology
Targeted immunological therapies offer safer and more effective treatments for skin conditions like eczema and psoriasis.
research Skin endocrinology and nutrition
Good nutrition and vitamins are important for healthy skin and can prevent diseases.
research Imported cutaneous Leishmaniasis in Japan
Albendazole can cause hair loss, and piroxicam can cause fixed drug eruption.
research Photobiomodulation mitigates DHT-induced apoptosis in dermal papilla cells via mitochondrial rescue and Wnt/TGF-β/BMP signaling modulation
Photobiomodulation helps protect hair follicle cells from damage caused by DHT.
research Antagonistic Effect of Iodides in Baldness and Toxicity due to Thallium Acetate
research Hypersensitivity Reactions to Homemade Topical Preparations.
Homemade skin products can cause allergic reactions, so use registered products if you have allergies.
research 574 Comparative analysis of quality of life impact in patients with autoimmune blistering disease
Patients with autoimmune blistering diseases experience a reduced quality of life, with the need for better measurement tools, especially for those with mucous membrane pemphigoid.
research Fe de errores
The document corrects a mistake by stating that pimecrolimus, not tacrolimus, is the drug that concentrates in the skin.
research Prevalence of skin lesions in a sample of Brazilian patients with inflammatory bowel disease
Brazilian patients with inflammatory bowel disease have a high rate of skin problems compared to healthy people.
research From Plants to Wound Dressing and Transdermal Delivery of Bioactive Compounds
Plant-based compounds can improve wound dressings and skin medication delivery.
research Risk of Autoimmune Skin Diseases Associated With Immune Checkpoint Inhibitors: A Pharmacovigilance Analysis Using the FAERS Database
Immune checkpoint inhibitors can increase the risk of autoimmune skin diseases, especially bullous pemphigoid.
research MARKETING ANALYSIS OF SUPPLYING THE PHARMACEUTICAL MARKET WITH DRUGS BASED ON BURCH (ARCTIUM LAPPA L.)
Burdock has potential for new pharmaceutical products due to its medicinal properties.
research 1436 Lesional skin histology in drug-induced hypersensitivity syndrome: A single center 10-year experience of 37 patients
Interface dermatitis is the most common skin change in drug-induced hypersensitivity syndrome.
research Topical Delivery of Tofacitinib in Dermatology: The Promise of a Novel Therapeutic Class Using Biodegradable Dendritic Polyglycerol Sulfates
A new carrier improves skin delivery of tofacitinib for treating inflammatory skin diseases.
research Application of the waiting time distribution in a nationwide screening of real‐world dermatology drug utilization for aberrant use patterns
Most dermatology drugs in Denmark are used correctly, with few unusual patterns.
research Biotin: A friend or foe in hair loss
Biotin doesn't help hair growth in healthy people and can cause health risks if overused.
research Pharmacological Inhibition of Stearoyl CoA Desaturase in the Skin Induces Atrophy of the Sebaceous Glands
Blocking SCD1 in the skin with XEN103 shrinks sebaceous glands in mice.
research Transfollicular Drug Delivery Systems
Transfollicular drug delivery can improve medication absorption through hair follicles.
research Physical and mechanical cues affecting biomaterial-mediated plasmid DNA delivery: insights into non-viral delivery systems
Biomaterials can improve non-viral gene delivery by enhancing DNA uptake and reducing toxicity.
research Field Cancerization: From Molecular Basis to Selective Field-Directed Management of Actinic Keratosis
Photodynamic therapy is the preferred treatment for skin precancer due to its effectiveness and safety.
research Controversies in off‐label prescriptions in dermatology: the perspective of the patient, the physician, and the pharmaceutical companies
The document concludes that doctors should carefully consider off-label drug use in dermatology and always inform patients, while more research is needed on the safety and effectiveness of such practices.
research Vitiligo
Vitiligo is now seen as a systemic disease with promising new treatments and may offer protection against some diseases.