4 citations
,
November 2011 in “InTech eBooks” Cultured epithelial autografts help treat burns by expanding skin cells, but challenges like cost and scarring persist.
April 2018 in “Journal of Investigative Dermatology” Culturing Dermal Papilla Cells and Hair Follicle Stem Cells in 3D conditions can significantly improve hair regeneration potential.
21 citations
,
December 2016 in “PLOS ONE” Scientists made skin stem cells from other human cells with over 97% efficiency, which could help treat skin conditions.
Researchers developed a cost-effective, ethical skin model using hairless guinea pig cells for toxicology studies.
July 1999 in “Journal of the American Academy of Dermatology” 44 citations
,
May 1997 in “Journal of Biological Chemistry” The human keratin 6a gene's specific sequences trigger expression in skin layers after injury.
July 2020 in “Research Square (Research Square)” A 3D co-culture model improved stem cell function and wound healing.
August 2025 in “Journal of Polymer Science” AcD scaffolds improve tissue repair and regeneration by combining stem cells with a supportive matrix.
March 2026 in “Experimental Dermatology” The new model helps understand and develop treatments for genetic skin disorders like AEC.
August 2019 in “Journal of Investigative Dermatology” Frog skin cells need the protein desmoplakin for proper development and cell layer formation.
5 citations
,
September 2012 in “Journal of Investigative Dermatology” Scientists can mimic hair disorders by altering genes in lab-grown human hair follicles, but these follicles lack some features of natural ones.
45 citations
,
December 1991 in “Annals of the New York Academy of Sciences” Adhesion molecules are crucial for the development of feathers and hair.
December 2025 in “Regenerative Biomaterials” The hydrogel effectively heals diabetic wounds by reducing inflammation, providing oxygen, and preventing infection.
8 citations
,
January 2022 in “Current topics in developmental biology/Current Topics in Developmental Biology”
1 citations
,
May 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” A special gel scaffold was made that speeds up wound healing and skin regeneration, even though it breaks down faster than expected.
January 2026 in “MEDS Clinical Medicine” Biophysical and metabolic factors in skin wounds are crucial for stem cell behavior and skin healing.
3 citations
,
March 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Zebrafish are useful for studying and developing treatments for human skin diseases.
31 citations
,
July 2023 in “Foods” 3D scaffolds are crucial for making lab-grown meat taste and feel like real meat.
August 2021 in “Oxford University Press eBooks” The skin is a complex organ that protects the body, regulates temperature, and has roles in immunity, hormone function, and vitamin D metabolism.
July 2025 in “Journal of Investigative Dermatology”
16 citations
,
April 2016 in “PLoS ONE” Negative pressure treatment improved skin thickness, blood vessel growth, and hair growth.
277 citations
,
July 2011 in “Journal of the Dermatology Nurses’ Association” The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.
106 citations
,
June 2009 in “BMC Genomics” Sea cucumbers have unique genes that help them regenerate their intestines.
5 citations
,
January 1993 in “PubMed” Retinoic acid can change skin structures in vertebrates, like turning scales into feathers or hair buds into glands.
38 citations
,
June 2018 in “Archives of Toxicology” Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.
20 citations
,
July 1987 in “Development Genes and Evolution”
12 citations
,
August 2016 in “Current opinion in genetics & development” Organs like hair follicles can renew themselves in complex ways, adapting to different needs and environments.
October 2014 in “Tesis Doctorals en Xarxa (Consorci de Serveis Universitaris de Catalunya)” Cell processes depend on time-of-day and protein complex flexibility for skin health.
49 citations
,
March 2014 in “Journal of Investigative Dermatology” Using the drugs AMD3100 and Tacrolimus together greatly improves skin healing and hair growth after a deep skin cut by increasing stem cells in the wound.
September 2016 in “Toxicology letters” The 5050 MHA42MCS45 hydrogel blend is suitable for repairing load-bearing soft tissues.