research Complete Blood Collection-based Systemic Inflammation Biomarkers as a Severity Biomarker in Alopecia Areata: A Cross-sectional Study
Higher inflammation markers are linked to more severe alopecia areata.
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research Microbial harmony in female reproductive health: exploring the impact of intestinal flora on ovarian function and disease pathogenesis
Gut bacteria affect female reproductive health and may help diagnose and treat related diseases.
research The role of multiomics in revealing the mechanism of skin repair and regeneration
Multiomics helps understand and improve skin healing and repair.
research Understanding human aging and the fundamental cell signaling link in age-related diseases: the middle-aging hypovascularity hypoxia hypothesis
Improving blood flow and oxygen levels in middle age may help prevent age-related diseases.
research Managing Skin Ageing as a Modifiable Disorder—The Clinical Application of Nourella® Dual Approach Comprising a Nano-Encapsulated Retinoid, Retilex-A® and a Skin Proteoglycan Replacement Therapy, Vercilex®
Nourella® effectively improves skin thickness and elasticity, reversing aging signs.
research Cellular Senescence and Aging in Myotonic Dystrophy
Myotonic Dystrophy may age cells faster, and drugs that target aging could be potential treatments.
research A symphony of signals: the intricate role of lncRNAs in dermatological disorders
lncRNAs are important for understanding and treating skin diseases.
research Human Hair as a Testing Substrate in the Era of Precision Medicine: Potential Role of ‘Omics-Based Approaches
Human hair shows promise for non-invasive medical testing, but more research is needed to standardize its use.
research DNA Methylation as an Epigenetic Memory Keeper during Skin Development and Regeneration
DNA methylation is essential for skin and hair follicle development, and could be a target for treating skin diseases.
research Grand challenges in dermatologic drug discovery: four priorities to transform skin disease treatment
Transforming skin disease treatment requires new strategies, better drug models, and patient-focused research.
research The Mitochondrial Blueprint of Skin Aging: From Damage Signals to Dermatologic Interventions
Targeting mitochondria can improve skin health and slow aging.
research 686 Topical melatonin unfolds differential anti-aging effects in human skin by inhibiting mTORC1 activity via TSC2 stimulation
Topical melatonin may reduce skin aging by inhibiting certain cellular pathways.
research Comparative Characterization of Human Meibomian Glands, Free Sebaceous Glands, and Hair-Associated Sebaceous Glands Based on Biomarkers, Analysis of Secretion Composition, and Gland Morphology
Meibomian glands are highly specialized and differ significantly from other sebaceous glands in structure and function.
research An overview about Therapeutic uses, clinical efficacy, safety and classes of Retinoids and its efficacy for Treatment of skin aging
Retinoids effectively treat skin aging but have safety and stability issues.
research Proteins observed in scalp hair from preschool children
Mothers have more hair proteins than their children, with age-related differences in protein patterns, and some proteins in hair could indicate early childhood development.
research Exosomes for Regeneration, Rejuvenation, and Repair
Exosomes show promise for tissue repair and regeneration with advantages over traditional cell therapies.
research Antioxidants and Mitochondrial Bioenergetics
Antioxidants may help improve mitochondrial health and could be used to treat diseases related to cell damage.
research Roles of Nutritional Selenium in Mouse Aging and Age‐related Degenerations
Selenium deficiency worsens aging symptoms in mice.
research Review of Hair Follicle Dermal Papilla cells as in vitro screening model for hair growth
Dermal Papilla cells are a promising tool for evaluating hair growth treatments.
research Premature aging syndromes: From patients to mechanism
Studying premature aging syndromes helps understand human aging and suggests potential treatments.
research TGF-β2 and collagen play pivotal roles in the spheroid formation and anti-aging of human dermal papilla cells
Collagen and TGF-β2 help maintain hair cell shape and youthfulness.
research Proteomic analysis of balding and non-balding mesenchyme-derived dermal papilla cells from androgenetic alopecia patients using on-line two-dimensional reversed phase-reversed phase LC–MS/MS
Found different proteins in balding and non-balding cells, giving insight into hair loss causes.
research Evaluation of NF-κB as a Novel Serum Biomarker in Androgenetic Alopecia Patients: A Case–Control Study
NF-κB levels can help diagnose and assess the severity of androgenetic alopecia.
research Causal associations between plasma proteins and prostate cancer: a Proteome-Wide Mendelian Randomization
Certain plasma proteins are linked to prostate cancer risk and could help in early detection and treatment.
research Quantifying long-term stress in brown bears with the hair cortisol concentration: a biomarker that may be confounded by rapid changes in response to capture and handling
Hair cortisol levels in brown bears can be affected by both long-term and short-term stress.
research Hair Cortisol as a Biomarker of Chronic Stress in Community-Dwelling Adults With Longstanding Multiple Sclerosis
Hair cortisol levels don't reliably indicate chronic stress in people with multiple sclerosis.
research The Pathobiology of Skin Aging
Skin aging is a complex process influenced by various factors, leading to wrinkles and sagging, and should be considered a disease due to its health impacts.
research Smoking and the skin
Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.
research Surface Lipids as Multifunctional Mediators of Skin Responses to Environmental Stimuli
Skin surface lipids are important for skin health and altering them could help prevent aging and treat skin conditions.
research Clinical and biological impact of the exposome on the skin
Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.