research Data-driven strategies for drug repurposing: insights, recommendations, and case studies
Drug repurposing can speed up and reduce costs in drug discovery, especially for cancer treatment.
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240-270 / 1000+ resultsresearch Topical Delivery of Tofacitinib in Dermatology: The Promise of a Novel Therapeutic Class Using Biodegradable Dendritic Polyglycerol Sulfates
A new carrier improves skin delivery of tofacitinib for treating inflammatory skin diseases.
research Validated HPTLC method for the simultaneous determination of alfuzosin, terazosin, prazosin, doxazosin and finasteride in pharmaceutical formulations
Method can accurately measure five BPH drugs at once.
research Effective holistic characterization of small molecule effects using heterogeneous biological networks
Integrating biological networks improves drug repurposing and ADR prediction.
research Classifications of patterned hair loss: a review
Different types of hair loss need specific treatments, and while many classification systems exist, each has its flaws; more research is needed to refine these systems and treatments.
research Comparison of pharmacokinetics and relative bioavailabilities of two kinds of finasteride tablets
research Core-shell and core-amphiphilic branched shell nanocarriers based on biodegradable hyperbranched polymers, as potential drug delivery systems
The new biodegradable nanocarriers safely and effectively deliver drugs into the skin.
research Photobiomodulation in 3D tissue engineering
PBM helps improve cell survival in 3D tissue engineering.
research Simple and Selective HPLC-UV/Vis Bioanalytical Method to Determine Aluminum Phthalocyanine Chloride in Skin Permeation Studies
A new method accurately measures a drug in skin for cancer therapy research.
research Biochemical approach on the conservation of drug molecules during hair fiber formation
Drugs can be incorporated into hair based on their chemical properties and hair pigmentation.
research Purpose-limited pharmaceutical product claims under the revised European Patent Convention: A camouflaged attack on generic substitution?
The revised European Patent Convention may limit generic drug use, affecting healthcare professionals' treatment choices.
research Pharmacophore Modeling and Three Dimensional Database Searching for Drug Design Using Catalyst: Recent Advances
The document concludes that Catalyst software is effective for drug design, identifying potent compounds for various medical conditions.
research Optimization and Characterization of <i>Cuscuta reflexa </i>Extract Loaded Phytosomes by the Box-Behnken Design to Improve the Oral Bioavailability
Phytosomal nanocarriers can significantly increase the bioavailability of Cuscuta reflexa extract.
research Ensuring safety in cytotoxic drug preparation: A systematic review of guidelines addressing education for pharmacy professionals
research Transfollicular drug delivery—Is it a reality?
Hair follicles may soon be used more for targeted and systemic drug delivery.
research Recent Trends and Future Prospects of Phytosomes: A Concise Review
Phytosomes improve the body's absorption of plant extracts for better health benefits.
research The New Classification Criteria of Systemic Lupus Erythematosus
The 2012 SLICC criteria provide an updated method for classifying Systemic Lupus Erythematosus.
research High-content drug screening for rare diseases
High-content screening is useful for finding new treatments for rare diseases and has led to FDA-approved drugs.
research Determination of finasteride in human plasma and its pharmacokinetics and relative bioavailability by HPLC-electrospray mass spectrometry
Two finasteride tablet formulations are bioequivalent.
research Solubilizing steroidal drugs by β-cyclodextrin derivatives
Using β-cyclodextrin derivatives improves the solubility and bioavailability of steroidal drugs.
research A MINI REVIEW ON PHOTO- BIOMODULATION- Novel approach
Photobiomodulation therapy shows promise in treating various health conditions by using specific light wavelengths.
research Authentication of herbs by physiological & morphological studies through HPTLC, ICP-MS, UV Spectroscopy, Genetic Engineering & PCR
Herbal medicines need strict quality control to ensure safety and authenticity.
research Liquid chromatographic-mass spectrometric method for determination of drug content uniformity of two commonly used dermatology medications in a split-tablet dosage form
Splitting non-scored tablets can lead to uneven drug distribution, posing risks.
research Patentability of dosage regime invention in the form of Swiss-type claim under Chinese patent law
Dosage regime inventions can be patentable in China, but legal uncertainty exists.
research Rp-HPLC Determination of Quercetin in a Novel D-α-Tocopherol Polyethylene Glycol 1000 Succinate Based SNEDDS Formulation: Pharmacokinetics in Rat Plasma
The new formulation greatly improved quercetin absorption in rats.
research Self-microemulsifying systems of Finasteride with enhanced oral bioavailability: multivariate statistical evaluation, characterization, spray-drying and in vivo studies in human volunteers
Improved Finasteride delivery for hair loss treatment.
research The Drug Reboot: Finding New Life in Old Formulations
Repurposing existing drugs can quickly and cheaply find new treatments for diseases.
research Pharma in the bedroom . . . and the kitchen. . . . The pharmaceuticalisation of daily life
The conclusion is that the increasing use of drugs for lifestyle reasons is a complex issue influenced by corporate profit, consumer behavior, and the medicalization of everyday life, with potential negative effects on personal well-being.
research FOLLICULAR LIPOSOMAL DELIVERY SYSTEMS
New liposomal formulations may improve delivery of treatments to hair follicles, potentially helping with hair loss.
research Scoring systems for pemphigus
The Pemphigus Disease Area Index and Autoimmune Bullous Skin Disorder Intensity Score are the best tools for assessing pemphigus severity.