research Carbobenzoxy-capped Phe-Lys(BODIPY TMR-X-acyloxymethyl ketone(QSY7)
Near-infrared probes can safely and effectively image cysteine protease activity for disease diagnosis.
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330-360 / 1000+ resultsresearch Advances and Perspectives on Bioelectronic and Atomic Nanogenerators for Anticancer Therapy
Bioelectronic nanogenerators show promise for cancer treatment but need better understanding and development.
research Redefining Drug Discovery: A Review of Drug Repurposing –Approaches, Benefits and Breakthroughs
Drug repurposing finds new uses for existing drugs, speeding up treatment availability and reducing costs.
research Structural characterization of cyclosporin A, C and microbial bio-transformed cyclosporin A analog AM6 using HPLC–ESI–ion trap-mass spectrometry
Researchers developed a method to identify and analyze cyclosporin compounds and their structures effectively.
research Biotechs target stagnant baldness market
New drug shows promise for better hair growth in baldness treatment.
research Novel Synthetic Steroid Derivatives: Target Prediction and Biological Evaluation of Antiandrogenic Activity
New steroid compounds may help with hormonal therapy and have potential benefits for glucose disorders, but more research is needed.
research Improving selective androgen receptor modulator discovery and preclinical evaluation
We need better ways to test and understand SARMs to make safer and more effective treatments.
research Engineered building bloks to print endogenous tissue and complex organs in vitro
New bio-ink can print complex tissues and organs.
research Role of Drug Repurposing in Sustainable Drug Discovery
Drug repurposing speeds up drug development, saves money, and has led to about a third of new drug approvals.
research Spatial and single-cell transcriptomics unravel the complex interplay between the body and medical implants
New technologies help us understand how the body reacts to medical implants, which can improve implant performance.
research In vivo delivery of CRISPR-Cas9 genome editing components for therapeutic applications
research Immunological challenges associated with artificial skin grafts: available solutions and stem cells in future design of synthetic skin
Artificial skin grafts face immune rejection, but stem cells may improve future designs.
research Programmable Artificial Skins Accomplish Antiscar Healing with Multiple Appendage Regeneration
Artificial skin can heal wounds without scars and regenerate hair, oil, and sweat glands.
research ApoBDs: a paradigm shift from cellular debris to therapeutic vehicles
ApoBDs, once seen as waste, are now viewed as potential tools for disease treatment and tissue repair.
research Testosterone-stimulated weanlings as an alternative to castrated male rats in the Hershberger anti-androgen assay
Using testosterone-stimulated weanling rats can effectively replace castrated rats for anti-androgen testing, reducing animal stress.
research Drug pipeline 2Q22 — a downturn in approvals
Drug approvals slowed in 2Q22, but notable drugs like Amvuttra, Camzyos, and Olumiant were approved.
research Chemical and green synthesis of nanoparticles and their efficacy on cancer cells
Green-synthesized nanoparticles can effectively target cancer cells, reducing side effects and improving treatment.
research 501 Next-generation in vitro testing: microfluidic models for aging, wound healing, and oral tissue analysis in safety, efficacy, and permeation studies
Microfluidic models improve testing for aging, wound healing, and oral tissue, reducing animal testing.
research Progress and prospects: gene therapy for performance and appearance enhancement
Gene therapy shows promise for enhancing physical traits but faces ethical, safety, and regulatory challenges.
research Counterfeit drugs and pharmaceutical preparations seized from the black market among bodybuilders
Many black market drugs for bodybuilders are fake and mislabeled.
research The future of cosmeceuticals
Future skincare will use advanced science for personalized anti-aging treatments.
research Advancements in Drug Repurposing: Examples in Psychiatric Medications
Old psychiatric drugs are increasingly being used for new purposes, and technologies like SmartCube® help create new drugs.
research Nanotechnology-Based Strategies for Hair Follicle Regeneration in Androgenetic Alopecia
Nanotechnology shows promise for better hair loss treatments but needs more research for safety and effectiveness.
research Natural Product-InspiredBis(trifluoromethyl) PhenylHydroxycinnamate Derivatives as Promising Nonsteroidal Inhibitorsof Human Steroid 5α-Reductase Type-1: Synthesis, InVitro, and In Silico Studies
Certain hydroxycinnamate derivatives may effectively inhibit enzymes linked to hair loss with low toxicity.
research Advances in Chronic Wound Management: The Role of Antibiofilm-Based Wound Dressings and Theranostic Innovations
Nanoparticle-based dressings and theranostic innovations improve chronic wound care by effectively targeting biofilms and offering precise treatment.
research Recent advances in oxasteroids chemistry
New methods to make oxasteroids show promise for medical treatments like osteoporosis and breast cancer.
research Stereocontrolled synthesis of all eight stereoisomers of the putative anti-androgen cyoctol
Scientists made all eight versions of a compound called cyoctol, but found it's not an anti-androgen and it fully breaks down in the skin.
research Clinical Translation of Targeted Protein Degraders
Targeted protein degraders show promise in treating cancer but need to target more diverse proteins.
research Microbial Biosurfactant as an Alternate to Chemical Surfactants for Application in Cosmetics Industries in Personal and Skin Care Products: A Critical Review
Microbial biosurfactants could be a safer and environmentally friendly alternative to chemical surfactants in cosmetics.
research Adaptive Triboelectric Nanogenerators for Long-Term Self-Treatment: A Review
Triboelectric nanogenerators can power wearable medical devices for long-term self-treatment and monitoring.