65 citations
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May 2006 in “Journal of Investigative Dermatology” Dexamethasone may influence hair growth by altering estrogen receptor activity in hair cells.
61 citations
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January 2011 in “PloS one” Notch signaling is essential for healthy skin and hair follicle maintenance.
56 citations
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October 2007 in “Journal of Biological Chemistry” Cathepsin L is essential for heart health and its absence causes heart problems and hair loss.
49 citations
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July 2000 in “Journal of Histochemistry & Cytochemistry” POMC-derived peptides are important for skin functions like immune response and stress management.
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June 2018 in “Frontiers in immunology” MDSC-Exo can treat autoimmune alopecia areata and promote hair regrowth in mice.
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May 2023 in “Preprints.org” Skin pigmentation varies due to genetics, UV exposure, and medications, with treatments available but requiring medical advice.
32 citations
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August 2016 in “Science Signaling” Alopecia areata patients show unique protein activity patterns, suggesting imbalanced signaling pathways.
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February 2021 in “Diabetes” Dock5 is important for skin healing and could help treat diabetic wounds.
25 citations
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January 2012 in “Proteome Science” Adipose stem cells show common protein changes as they grow, especially involving S100A6.
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July 2023 in “Journal of Functional Biomaterials” Bubble-based systems show promise for precise, targeted drug delivery and diagnosis, especially in cancer treatment.
22 citations
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December 2015 in “The journal of investigative dermatology/Journal of investigative dermatology” A mouse gene mutation increases the risk of skin cancer.
22 citations
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August 2015 in “PloS one” Keratin from hair binds well to gold and BMP-2, useful for bone repair.
22 citations
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July 2015 in “PloS one” Foxp1 helps control hair stem cell growth and response to stress during hair growth cycles.
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November 2023 in “International Journal of Molecular Sciences” Melatonin helps reduce aging signs in human eyelid skin.
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January 2022 in “Biomaterials Science” RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.
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January 2021 in “Theranostics” The targeted nanohybrids effectively reduced psoriasis symptoms and improved skin health.
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February 2017 in “Molecular Medicine Reports” Activating Notch signaling can kill basal cell carcinoma cells.
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September 2020 in “Animals” circRNA-1926 helps goat stem cells turn into hair follicles by affecting miR-148a/b-3p and CDK19.
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January 2017 in “Polymers” Polyelectrolytes can improve cell surfaces for better medical applications.
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July 2015 in “Developmental Dynamics” Orai1 protein is crucial for tooth development and affects enamel thickness and mineralization.
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September 2022 in “Frontiers in immunology” Ifidancitinib, a JAK inhibitor, effectively regrows hair in mice with alopecia by tiring out harmful T cells.
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August 2020 in “Nutrients” Ginseng extracts protect brain cells and reduce damage in diabetic rats.
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January 2020 in “Indian Dermatology Online Journal” Female pattern hair loss has multiple causes and treatments, with new therapies showing promise.
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April 2025 in “Pharmaceutics” New treatments like plant extracts, nanocarriers, and 3D bioprinting show promise for hair loss, but more research is needed.
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July 2022 in “Journal of Medicinal Chemistry” Adding a second method to PROTACs could improve cancer treatment.
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June 2023 in “Cells” Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.
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June 2022 in “Microorganisms” We need safe, affordable drugs to fight coronaviruses effectively.
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May 2024 in “ACS Applied Materials & Interfaces” PCL nanoscaffold-based liver spheroids are effective for drug screening and studying liver toxicity.
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August 2022 in “Journal of Nanobiotechnology” Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.
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September 2022 in “Communications biology” Omega-6 fats in certain cells boost male hormone production.