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The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.

CREB, a protein that can promote cancer traits, is controlled by β-catenin in skin cancer cells.

A specific molecular switch, driven by MAPK/ERK signaling, helps spiny mice heal wounds by regenerating skin instead of forming scars.

Activating autophagy might reverse skin fibrosis.

A gene called BMAL1 plays a role in controlling hair growth.

Alpha-MSH affects mitochondrial function, and MC1R mutations may increase skin aging.

Hedgehog signaling is crucial for hair development, cadherins affect cell adhesion, neutrophils play a role in skin lesions, and BP230 autoantibodies impact skin stability.

Folliculin helps regulate energy and nutrient sensing, impacting Birt–Hogg–Dubé syndrome.

Mathematical modeling helps understand and predict the MAPK cell signaling pathway.

A protein called CBP is found in prostate cancer and can increase the effectiveness of certain prostate cancer treatments.

EdnrB signaling helps melanocyte stem cells regenerate and could be targeted to treat pigmentation issues.

Normal human melanocytes can avoid cell death through multiple pathways.

Hedgehog pathway inhibitors could be effective in treating melanoma.

Genetic mutation and carcinogen treatment are both needed for skin cancer to develop in these specific mice.

SM04755 may be an effective topical treatment for psoriasis.

The study suggests that motor neurons created from stem cells of patients with spinal and bulbar muscular atrophy show signs of the disease, including changes in protein levels and cell functions.

Gab1 protein is crucial for hair growth and stem cell renewal, and Mapk signaling helps maintain these processes.

Scientists made a mouse that shows how a specific protein in the skin changes and affects hair growth and shape.

High levels of ERK activity are key for tissue regeneration in spiny mice, and activating ERK can potentially redirect scar-forming healing towards regenerative healing in mammals.

BAP1 mutations are rare in pediatric melanocytic tumors and may develop later in life.

Compounds from Pterocarpus indicus may help treat benign prostatic hyperplasia by stopping cell growth.

The hedgehog signalling pathway is key in skin development and basal cell carcinoma, offering insights for prevention and treatment.

Removing Gsdma1/2/3 genes reduces skin cell overgrowth by blocking a specific cell pathway.

Melatonin stops melanin production after tyrosinase action, with cyclic GMP mimicking this effect.

YAP1 helps fat cell formation by influencing the Hippo pathway.

MCPIP1 in myeloid cells is important for skin cancer development and healthy hair growth.

TTNPB helps turn stem cells into neural stem cells, improving depression-like behaviors in rats.

BRG1 is essential for skin cells to move and heal wounds properly.

Inhibiting AP1 in mice skin causes structural changes and weakens the skin barrier.

Two microRNAs in stem cell exosomes help treat hair loss by targeting a specific signaling pathway.