The review provides a comprehensive synthesis of the current understanding of insect chorion biogenesis, focusing on the cellular mechanisms, gene regulation, biochemical composition, and structural diversity involved in eggshell formation, particularly in D. melanogaster. It highlights the differentiation and specialization of follicle cells, which are crucial for eggshell synthesis, and the temporal regulation of chorion gene expression necessary for the sequential production of eggshell layers. The biochemical composition includes structural proteins, carbohydrates, and lipids, which undergo post-translational modifications to stabilize the eggshell. The document also emphasizes the hierarchical organization of the eggshell's multilayered architecture and the morphological diversity of the chorion across different insect taxa, reflecting evolutionary adaptations. Additionally, it discusses the potential of using modern molecular tools like RNA interference and CRISPR/Cas9 for innovative pest management strategies.
November 2025 in “Veterinary and Animal Science” Camel hair structure, not color, helps camels stay cool in the desert.
3 citations
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March 2020 in “Zenodo (CERN European Organization for Nuclear Research)” Natural herbs may help hair growth, but more research is needed.
Understanding hair follicle structure and techniques improves hair restoration outcomes.
January 2025 in “Journal of Cosmetic Dermatology” Poor nutrition, higher BMI, and stress may worsen seborrheic dermatitis.
4 citations
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March 2024 in “Food & Nutrition Research” A ketogenic diet helps reduce weight, BMI, waist size, and fat in overweight women with PCOS.
November 2025 in “Medicina” Alopecia areata may be linked to changes in body fat but not to heart or artery issues.
53 citations
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July 2016 in “Cosmetics” Future hair cosmetics will be safer and more effective.
50 citations
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February 2022 in “Nanomaterials” Nanomaterials show promise in improving wound healing but require more research on their potential toxicity.
21 citations
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March 2025 in “Journal of Extracellular Vesicles” Hydrogels can enhance stem cell activity, but more research is needed to optimize their use.
11 citations
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September 2016 in “Archives of Dermatological Research” People with denser forearm hair have a higher risk of certain skin cancers.
September 2024 in “Heliyon” Repeated hair dyeing significantly damages hair.
103 citations
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December 2021 in “Journal of biological rhythms” Shift work disrupts the body's natural clock, leading to health problems.
66 citations
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May 2014 in “Conservation Physiology” Grizzly and black bears have different stress and hormone responses to salmon availability, influenced by nutrition and social competition.
29 citations
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October 2020 in “eLife” Higher testosterone levels can increase the risk of certain diseases like type 2 diabetes in women and prostate cancer in men, but can also protect against autoimmune diseases and hair loss. It also affects body fat and bone density.
16 citations
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November 2021 in “Antioxidants” Managing oxidative stress might help treat low testosterone and related chronic diseases in aging men.
1 citations
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January 2017 in “Journal of rare disease research & treatment” Obesity is common in PCOS patients and early treatment is important for their heart and metabolic health.
December 2025 in “Biomedicines” Addressing body image and weight can help improve female sexual dysfunction.
September 2023 in “The Journal of clinical endocrinology and metabolism” Genetic risk for PCOS can affect children's growth, metabolism, and development from early life into adulthood.
April 2023 in “JMIR Research Protocols” The study aims to create a model to predict health attributes using diverse health data from Japanese adults.
59 citations
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September 2003 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” Epitestosterone may counteract testosterone's effects and has roles in body processes like prostate growth and hair distribution.
22 citations
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May 2019 in “Animals” High hair cortisol levels indicate stress in cows due to poor shelter conditions and health issues.
22 citations
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September 2011 in “Journal of Investigative Dermatology” TCF/Lef1 is essential for skin barrier function by regulating lipid metabolism.
8 citations
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January 2020 in “PeerJ” Alopecia Areata causes significant structural and compositional changes in hair.
5 citations
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October 2021 in “Clinical, cosmetic and investigational dermatology” Japanese patients with alopecia areata often have a higher BMI and consume more vitamin C, fruit, and retinol, which may affect their condition's development or severity.
February 2026 in “American Journal Of Pathology” Skin organoids can mimic human skin responses to injury and inflammation, making them useful for studying skin diseases and testing treatments.
November 2025 in “Frontiers in Psychiatry” People with androgenetic alopecia often experience more anxiety, depression, and lower self-esteem.
August 2025 in “Cosmetics” Cosmeceuticals like sunscreens may trigger frontal fibrosing alopecia, but more research is needed.
February 2025 in “International Journal of Molecular Sciences” Altered lipid pathways in diabetic women may cause premature greying.
July 2024 in “Journal of Investigative Dermatology” Losing both ERBB2 and ERBB3 receptors in mice causes significant skin problems and inflammation.