78 citations
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November 2008 in “Fertility and Sterility” Amenorrhea is relatively rare and initial testing should check FSH, TSH, and prolactin levels.
57 citations
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January 2019 in “Stem Cell Research & Therapy” OCT4 helps hair stem cells renew and fight aging, potentially aiding hair regrowth.
January 2012 in “Infoscience (Ecole Polytechnique Fédérale de Lausanne)” Human thymus has stem cells that can self-renew and maintain their identity.
4 citations
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January 2014 in “Stem Cell Discovery” Stem cells can be reprogrammed for various treatments, but safety and expansion challenges remain.
147 citations
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September 2006 in “Developmental Cell” Too much Smad7 changes skin and hair development by breaking down a protein called β-catenin, leading to more oil glands and fewer hair follicles.
February 2025 in “Stem Cell Research & Therapy” Maintaining healthy mitochondria may help treat hair loss.
164 citations
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February 2010 in “Journal of Cell Science” Human dermal stem cells can become functional skin pigment cells.
14 citations
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March 2015 in “Stem Cell Research & Therapy” ABCG2 protein marks stem-like skin cells in human epidermis.
1 citations
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July 2023 in “Communications biology” Removing Mediator 1 from certain mouse cells causes teeth to grow hair instead of enamel.
34 citations
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January 2013 in “Frontiers in genetics” Stem cells can help other stem cells by producing supportive factors.
84 citations
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February 2015 in “Experimental Dermatology” PPARγ is crucial for skin health but can have both beneficial and harmful effects.
35 citations
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July 2022 in “Frontiers in Cell and Developmental Biology” Proper mTOR signaling is crucial for healthy skin and preventing skin diseases.
25 citations
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August 2007 in “Molecular Therapy” Researchers found a safe and effective way to pick genetically modified skin cells with high growth potential using CD24.
1201 citations
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January 2010 in “Science” Active and quiescent stem cells work together in mammals to maintain and repair tissues.
180 citations
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January 2011 in “EMBO Reports” A combined approach is needed to fully understand adult stem cells, with genetic lineage-tracing being crucial.
30 citations
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February 2023 in “Journal of Investigative Dermatology” OX40-targeted therapies may help treat skin diseases by reducing inflammation and balancing immune responses.
17 citations
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November 2015 in “Oxidative Medicine and Cellular Longevity” Fibroblast Growth Factor-9 helps repair heart damage after a heart attack by creating new blood vessels, especially in diabetics.
5 citations
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June 2022 in “Journal of Oncology” Blocking the Hedgehog pathway may help overcome drug resistance in multiple myeloma.
387 citations
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May 2019 in “International Journal of Molecular Sciences” Adipose-derived stem cells are promising for regenerative medicine due to their accessibility, versatility, and low risk of immune rejection.
5 citations
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November 2024 in “Biomedicine & Pharmacotherapy” The chitosan-peptide system helps cartilage regeneration using fat-derived cells.
1 citations
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January 2020 in “Microscopy research” Researchers successfully grew hair follicle stem cells from mice and humans, which could be useful for tissue engineering and regenerative medicine.
April 2017 in “Journal of dermatological science” Human hair follicles can produce stem cells that turn into heart muscle cells.
1036 citations
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August 2019 in “Cells” Mesenchymal stem cells can help repair body tissues with low risk of rejection.
142 citations
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February 2016 in “Science” Foxc1 helps keep hair follicle stem cells inactive, preventing hair loss.
13 citations
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November 2023 in “International Journal of Nanomedicine” Nanofiber scaffolds show promise for improving nerve healing.
April 2024 in “Archiv EuroMedica” Platelet-Rich Plasma therapy helps increase hair density and regrowth for some types of hair loss.
November 2011 in “Molecular Cancer Therapeutics” The Hedgehog signaling pathway is linked to cancer development, and targeting it with inhibitors shows promise but faces challenges like resistance.
January 2026 in “Burns & Trauma” RNA modifications help heal wounds and could lead to new treatments.
48 citations
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January 2015 in “Indian Journal of Dermatology, Venereology and Leprology” Vitamin D is important for skin health and can help treat psoriasis, atopic dermatitis, and vitiligo.
7 citations
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January 2017 in “Stem Cells International” Neural organoids show promise for future CNS disease treatments.