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Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

Blocking CYP17A1 enzyme may help improve certain brain function issues related to dopamine.

Women with PCOS have higher 5alpha-reductase activity, affecting steroid levels.

New steroids were patented as effective for treating acne, hair loss, and other conditions related to hormones.

Finasteride is extensively metabolized in the body, affecting its effectiveness and safety.

Testosterone affects hair loss, acne, and excessive hair growth, and antiandrogens can help treat these conditions.

The study created a model to help design new inhibitors for steroidal 5α-reductase enzymes.

Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.

Some women with excess hair growth have a hormone condition that can't be diagnosed by blood or urine tests alone.

Steroid 5α-reductase evolved from protists and diversified in eukaryotes, with specific roles in mammals and plants.

Affected males are born with ambiguous genitalia, raised as females, but develop male traits at puberty due to enzyme deficiency.

Mitotane changes steroid breakdown, affecting cortisol availability.

Finasteride, when taken daily, lowers dihydrotestosterone levels but doesn't noticeably affect adrenal steroid production, except by blocking the 5 alpha-reductase enzyme.

Finasteride harms Daphnia magna's reproduction and metabolism.

Modified steroidal inhibitors showed promise in treating hormone-dependent cancers.

Inhibitors of the enzyme 5 alpha-reductase could potentially treat disorders like prostate cancer and baldness.

A substance called Compound 2g can strongly block STS (a hormone-related enzyme) without affecting estrogen levels, making it potentially good for treating breast cancer.

New steroids were effective in blocking male hormone receptors in hamster prostates.

Certain interactions help prepare the androgen receptor for pairing and activation, which is important for its role in development and disease.

Neurosteroids regulate synaptic inhibition in the spinal cord and may help manage spinal pain.

Women with PCOS have higher 5alpha-reductase activity, affecting steroid levels.

Certain enzymes react strongly with some hormones in rat skin during hair growth, mainly in sebaceous glands and hair sheaths.

A genetic defect causes males in some Mediterranean populations to be born with ambiguous genitalia and develop male traits at puberty.

The compound 4c effectively inhibits the enzyme linked to hair loss.

Dutasteride may reduce insulin sensitivity and increase body fat.

Androgens can affect glucocorticoid signaling in specific mouse brain areas.

Human hair follicles can process steroid hormones like DHEA.