September 2019 in “Journal of Investigative Dermatology” Scientists used stem cells to create a model of the skin disease Epidermolysis Bullosa simplex, which helped them understand its molecular mechanisms and could aid in finding treatments.
10 citations
,
November 2015 in “American Journal of Primatology” Monkeys with more anxious or inhibited temperaments tend to have less hair loss.
9 citations
,
March 2019 in “Molecular & cellular proteomics” Reductive stress messes up collagen balance and alters cell signaling in human skin cells, which could help treat certain skin diseases.
November 2024 in “Journal of Investigative Dermatology” Genetic defects in the Wnt/PCP pathway may cause congenital yellow nail syndrome.
July 2026 in “bioRxiv (Cold Spring Harbor Laboratory)” FAKΔe4 helps cells sense and respond to different stiffness levels in their environment.
4 citations
,
November 2020 in “Journal of Investigative Dermatology Symposium Proceedings” The Brigham Eyebrow Tool for Alopecia is a simple and reliable way to measure eyebrow hair loss.
July 2025 in “International Journal of Trichology” A 6-year-old boy's leg hair loss was due to friction from sitting cross-legged, and it usually resolves on its own.
1 citations
,
September 1998 in “Journal of Advancement in Medicine” Thiamin deficiency might cause hair loss and mental health issues.
26 citations
,
October 1998 in “Experimental Dermatology” A keratin hHb6 mutation causes a hair disorder with varying severity, influenced by other factors.
39 citations
,
July 2015 in “British Journal of Dermatology” The pseudo 'fringe sign' can also appear in frontal fibrosing alopecia, not just in traction alopecia, showing that this condition may be more common than thought.
245 citations
,
January 1998 in “Genes & Development” Hoxc13 gene is essential for hair, nail, and papilla development.
99 citations
,
August 2009 in “Nature Genetics” Removing both Atr and Trp53 genes in adult mice causes severe tissue damage and death due to DNA damage.
Aluminum phosphide poisoning can cause horizontal nail grooves and hair loss.
February 2013 in “Journal of the American Academy of Dermatology” Uncombable hair syndrome causes dry, frizzy hair that can't be combed flat, seen in a young child.
October 2020 in “Pediatrics in Review” The newborn was diagnosed with a rare skin disorder causing blisters, which requires careful wound care and family support.
2 citations
,
December 2013 in “The Journal of Dermatology”
10 citations
,
January 2012 in “International Journal of Trichology” The study found no link between anxiety, vitamin B12, folate, TSH, ferritin, zinc levels, and trichodynia in telogen alopecia patients.
46 citations
,
October 2018 in “Neuroscience Bulletin”
12 citations
,
November 1987 in “Pediatric dermatology” Four children had unmanageable pale blond hair due to uncombable-hair syndrome.
January 2017 in “Durham e-Theses (Durham University)” Chemical stressors damage hair structure but the skin's outer layer protects living cells.
1 citations
,
December 2017 in “Anais Brasileiros de Dermatologia” Frontal fibrosing alopecia can mimic traction alopecia but has distinct features like facial papules and eyebrow thinning.
50 citations
,
October 2007 in “Archives of Dermatological Research” 30 citations
,
August 1984 in “Journal of the American Academy of Dermatology” Low-sulfur hair syndrome can cause UVB sensitivity and testicular failure.
5 citations
,
March 2015 in “Clinical and Experimental Dermatology” Chemotherapy caused a woman's permanent hair loss and early menopause.
3 citations
,
January 2019 in “Journal of Dermatology” The p.P25L mutation in the KRT5 gene causes a rare skin condition that worsens over time and may lead to hair loss starting in young adulthood.
February 2019 in “Americanae (AECID Library)” Selenium and zinc deficiency in sheep leads to thyroid and skin problems.
73 citations
,
June 2010 in “PLoS Genetics” A gene mutation in mice causes hair loss, weak bones, and protein buildup, showing how protein processing issues can lead to diseases.
12 citations
,
January 1934 in “Proceedings of the Royal Society of London Series B Containing Papers of a Biological Character” Stretched hair has a similar structure to natural silk, showing hair's elasticity involves reversible changes within its molecules.
98 citations
,
December 2015 in “The Journal of Cell Biology” Keratin is crucial for skin barrier formation and affects mitochondrial function.
5 citations
,
March 2025 in “Tissue Engineering and Regenerative Medicine”