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Treating classic 21-hydroxylase deficiency requires precise glucocorticoid dosing and attention to individual patient needs, with new treatments showing promise.

Testosterone may have a dual role in COVID-19, potentially worsening outcomes in men, and testosterone therapy could help some patients, but more research is needed.

Sex hormones may affect COVID-19 severity, with estrogen possibly reducing risk and testosterone potentially increasing it.

Azathioprine is the most continued treatment for chronic alopecia areata over a year, often with added low-dose prednisolone.

High adrenal sex hormones in dogs with hypercortisolemia can mislead adrenal hyperplasia diagnosis.

Inhaled steroids in children may cause excessive hair growth and not always go away after stopping the medication.

Common dermatology drugs were considered but are controversial for COVID-19 treatment.

Neurosteroids help control dopamine responses in the brain.

Unregulated glucocorticoid use can disrupt hormone balance and cause serious health issues.

Short-term diabetes can cause changes in brain steroids, cholesterol balance, and mitochondrial function.

High and low doses of prednisolone helped 62% of children with severe alopecia regrow hair with some weight gain and mild acne as side effects.

Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.

New steroid derivatives show promise as anticancer agents, even against resistant cells.

Oral pulse steroids reduce TNF-α levels, improving alopecia areata.

Combining cytostatic and steroid drugs effectively treats systemic lupus erythematosus.

A woman developed Cushing syndrome and adrenal insufficiency from using fluticasone and ritonavir together.

Systemic steroids effectively treated severe nail issues in a card illusionist with alopecia areata.

GABAergic steroid precursors reduce ethanol withdrawal symptoms in certain mice.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Systemic retinoids do not increase COVID-19 risk or severity.

A boy with a rare skin condition and kidney disease improved with cyclosporine after steroids failed, suggesting a new treatment approach.

Using topical steroids for acne is a bad idea and causes many skin problems.

Compounds 15, 20, and 25 are strong inhibitors of human steroid 5α-reductase type 2.

COVID-19 can cause skin problems and affect dermatology treatments, with recommendations for skin care and cautious use of certain drugs.

Improper steroid use can cause skin issues like rosacea, which may improve after stopping the steroid and using benzoyl peroxide.

Cortisone tapering may help improve severe myasthenia gravis and alopecia areata after thymectomy.

Steroid hormones change the size, charge, and stability of DPPC liposomes.

Careful dosing and monitoring are crucial to prevent adrenal insufficiency when using ketoconazole for Cushing's disease.

Norethisterone (jenapharm) therapy is effective for endometrial cancer.

Mutants of CYP154C2 enzyme significantly improved steroid conversion efficiency.