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Advances in the Study of Stem-Cell-Enriched Hair Follicle Bulge Cells: A Review Featuring Characterization and Isolation of Human Bulge Cells

research Advances in the Study of Stem-Cell-Enriched Hair Follicle Bulge Cells: A Review Featuring Characterization and Isolation of Human Bulge Cells

16 citations , January 2007 in “Dermatology”

Scientists have made progress in understanding hair follicle stem cells, identifying specific genes and markers, and suggesting their use in treating hair and skin conditions.

Dietary Supplementation with Essential Oils and Cobalt for Improving Growth Performance, Meat Quality, and Skin Cell Capacity of Goats

research Dietary supplementation with Essential-oils-cobalt for improving growth performance, meat quality and skin cell capacity of goats

32 citations , July 2018 in “Scientific Reports”

Essential-oils-cobalt improves goat growth and product quality.

research A null mutation in the cystatin M/E gene of ichq mice causes juvenile lethality and defects in epidermal cornification

66 citations , October 2002 in “Human molecular genetics online/Human molecular genetics”

A gene mutation in mice causes skin defects and early death.

research CDK4/6 inhibition mitigates stem cell damage in a novel model for taxane‐induced alopecia

58 citations , September 2019 in “EMBO Molecular Medicine”

CDK4/6 inhibitors can protect hair cells from chemotherapy damage.

research Hair follicle stem cells isolated from newborn Yangtze River Delta White Goats

16 citations , February 2019 in “Gene”

Researchers found a good way to isolate hair follicle stem cells from newborn goats for further study.

research Stem cells supporting other stem cells

34 citations , January 2013 in “Frontiers in genetics”

Stem cells can help other stem cells by producing supportive factors.

research From Hair to Cornea: Toward the Therapeutic Use of Hair Follicle-Derived Stem Cells in the Treatment of Limbal Stem Cell Deficiency

135 citations , October 2010 in “Stem Cells”

Hair follicle stem cells can help treat eye surface issues by becoming corneal cells.

research Cytokeratin 7 and 20

1 citations , February 2012 in “InTech eBooks”

CK7 and CK20 help identify and classify tumors for accurate cancer diagnosis.

research Effect of CUX1 on the Proliferation of Hu Sheep Dermal Papilla Cells and on the Wnt/β-Catenin Signaling Pathway

6 citations , February 2023 in “Genes”

CUX1 boosts sheep hair cell growth and affects curl patterns.

research 19 Adipose stem cell exosome (ASCE): next generation regenerative therapeutics for atopic dermatitis

November 2023 in “Journal of Investigative Dermatology”

Adipose stem cell exosomes may effectively treat atopic dermatitis by reducing inflammation and improving skin health.

research Modulation of Dermal Cell Activity During Hair Growth in the Rat

55 citations , February 1975 in “Journal of Cutaneous Pathology”

Dermal cell activity increases during hair growth in rats.

TCL1 Transgenic Mouse Model as a Tool for the Study of Therapeutic Targets and Microenvironment in Human B-Cell Chronic Lymphocytic Leukemia

research TCL1 transgenic mouse model as a tool for the study of therapeutic targets and microenvironment in human B-cell chronic lymphocytic leukemia

38 citations , January 2016 in “Cell Death and Disease”

The TCL1 transgenic mouse model is useful for understanding human B-cell leukemia and testing new treatments.

research 447 Skin-Associated Cartilage Consists of Lipid-Filled Cells That Modify Hair Growth via BMP and WNT Signaling

November 2025 in “Journal of Investigative Dermatology”

Skin-associated cartilage cells can influence hair growth by altering specific signaling pathways.

research Comparative gene expression analysis of nestin-expressing hair follicle-derived cells

June 2026 in “Scientific Reports”

Nestin-expressing hair follicle cells may be useful for nerve repair and regeneration.

research Differential Expression of CXCL12 in Human and Mouse Hair: Androgens Induce CXCL12 in Human Dermal Papilla and Dermal Sheath Cup

December 2024 in “International Journal of Molecular Sciences”

Targeting CXCL12 may help treat hair loss caused by androgens.

research A Multiaxial Bioreactor Integrated with an Environmental Monitoring System for Tissue‐Engineered Skin Grafts

January 2026 in “Advanced Healthcare Materials”

The new bioreactor improves skin grafts by evenly stretching cells and monitoring conditions for better growth.

Humanized CXCL12 Antibody Delays Onset and Modulates Immune Response in Alopecia Areata Mice: Insights from Single-Cell RNA Sequencing

research Humanized CXCL12 antibody delays onset and modulates immune response in alopecia areata mice: insights from single-cell RNA sequencing

7 citations , October 2024 in “Frontiers in Immunology”

A humanized CXCL12 antibody may delay and treat alopecia areata by altering the immune response.

research 519 Phase I/IIa clinical trial for recessive dystrophic epidermolysis bullosa using genetically corrected autologous keratinocytes

5 citations , April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology”

The gene therapy showed significant wound healing and was safe for treating severe RDEB.

research Reconstructed Tissue-engineered Skin with ES Cell-derived Epidermal Stem Cells and Collagen Sponge

January 2006 in “Journal of Sun Yat-sen University”

Engineered skin using stem cells and collagen sponge effectively healed and regenerated complex skin features in mice.

research Nestin-Expressing Hair Follicle-Accessible Pluripotent Stem Cells for Nerve and Spinal Cord Repair

32 citations , January 2014 in “Cells tissues organs”

Hair follicle stem cells can help repair nerve and spinal cord injuries.

The Role of Box A of HMGB1 in Enhancing Stem Cell Properties of Human Mesenchymal Cells: A Novel Approach for the Pursuit of Anti-Aging Therapy

research The Role of Box A ofHMGB1in Enhancing Stem Cell Properties of Human Mesenchymal Cells: A Novel Approach for the Pursuit of Anti-aging Therapy

1 citations , January 2023 in “In vivo/In Vivo”

Box A of HMGB1 can improve stem cell function, aiding anti-aging therapy.

research Plant cell culture as emerging technology for production of active cosmetic ingredients

67 citations , June 2018 in “Engineering in Life Sciences”

Plant cell culture is a promising method for creating sustainable and high-quality cosmetic ingredients.

research Current Status of the Applications of Conditioned Media Derived from Mesenchymal Stem Cells for Regenerative Medicine

3 citations , January 2023 in “Physiological Research”

Conditioned media from mesenchymal stem cells show promise for tissue repair and disease treatment, but more research is needed on their safety and effectiveness.

research Patterns of expression of trichocytic and epithelial cytokeratins in mammalian tissues II. Concomitant and mutually exclusive synthesis of trichocytic and epithelial cytokeratins in diverse human and bovine tissues (hair follicle, nail bed and matrix, lingual papilla, thymic reticulum)

187 citations , May 1988 in “Differentiation”

Trichocytic cytokeratins are found in hair, nails, tongue, and thymus cells, showing complex regulation in tissue development.

research Towards expansion of human hair follicle stem cells in vitro

14 citations , April 2011 in “Cell Proliferation”

Scientists can grow human hair follicle stem cells in a lab without changing their nature, which could help treat hair loss.

research Colon Cancer Stem Cells: Promise of Targeted Therapy

411 citations , April 2010 in “Gastroenterology”

Targeting colon cancer stem cells might lead to better treatment results.

research Beyond Comfortable: A Removable Antibacterial Electroconductive Cellulose Nonwoven Dressing for Accelerated Wound Healing

2 citations , December 2025 in “Nano Letters”

The study presents a novel tannin-modified cellulose-polypyrrole nonwoven dressing (TA/Cell@PPy) designed to accelerate wound healing by combining antimicrobial protection with electrotherapy. The dressing utilizes tannic acid for antibacterial activity against S. aureus and E. coli, and conductive polypyrrole to enhance endogenous electric fields, promoting re-epithelialization. In vivo evaluations show that TA/Cell@PPy significantly speeds up wound closure through enhanced granulation tissue, optimized collagen matrix organization, and stimulated angiogenesis. Its biomimetic nanofibrous architecture ensures biocompatibility and prevents secondary trauma during dressing changes, offering a promising solution for complex wound management by addressing infection control and tissue regeneration simultaneously.