46 citations
,
October 2012 in “Dermatologic Clinics” Female pattern hair loss diagnosed by scalp appearance, treated with combined therapies and targeted approaches.
35 citations
,
February 2002 in “Journal of Radiological Protection” Caffeine reduces radiation skin damage but doesn't affect tumor treatment.
21 citations
,
September 1966 in “Toxicology and Applied Pharmacology” Caffeine becomes more toxic in rats when food intake is reduced by over 50%.
12 citations
,
March 2012 in “ATLA. Alternatives to laboratory animals” Hair follicles significantly affect the skin absorption of some drugs.
6 citations
,
August 2021 in “International Journal of Cosmetic Science” Using antioxidants on the scalp can make it healthier and decrease hair loss.
2 citations
,
August 2020 in “Chemical and Pharmaceutical Bulletin” Rubbing increases drug absorption through hair follicles.
1 citations
,
March 2022 in “Protection convergence” Fermented green coffee beans may be good for scalp and hair health cosmetics.
1 citations
,
February 2020 in “PubMed” The topical solution improved hair density and appearance in men with androgenetic alopecia.
May 2026 in “Jurnal Riset Kefarmasian Indonesia” Robusta coffee beans have high caffeine content, useful for products like hair growth stimulants.
Most ingredients in hair loss shampoos lack strong evidence of effectiveness.
September 2025 in “medRxiv (Cold Spring Harbor Laboratory)” Using Centella asiatica EV and growth factors improves scalp health and hair growth.
September 2025 in “Journal of Drug Delivery Science and Technology” Vitamin D3-coated nanoparticles effectively deliver caffeine for alopecia treatment with minimal side effects.
The TrichoConcept™ line is effective for personalized hair loss treatments.
January 2024 in “Indonesian Journal of Pharmaceutical Education” The Caffein Herbasome® cream is stable and suitable for skin use.
November 2013 in “Journal of Mazandaran University of Medical Sciences” Minoxidil with caffeine works better for hair loss than minoxidil alone.
5 citations
,
October 2020 in “Giornale italiano di dermatologia e venereologia” The phyto-caffeine shampoo reduced hair loss and improved hair strength in women with hair thinning.
2 citations
,
January 2012 in “International Journal of Trichology” Coffee and tea might help hair growth in balding individuals, but side effects and alternative uses are being considered.
21 citations
,
November 2012 in “Plastic and Reconstructive Surgery” Both genetic and lifestyle factors significantly affect female hair loss.
November 2023 in “Hair transplant forum international” Caffeine can stimulate hair growth, but the best dose and frequency for hair loss treatment are still unknown.
January 2025 in “International Journal of Molecular Sciences” Nanoparticles have diverse applications, including promising cancer treatments and hair growth solutions.
Adenosine and caffeine can promote hair growth.
March 2007 in “International Society of Hair Restoration Surgery” Caffeine may help hair grow and manage hair loss.
3 citations
,
January 2023 in “International Journal of Cosmetic Science” Coffee and its by-products are promising for skin health benefits in cosmetics and help reduce environmental impact.
2 citations
,
January 2014 Improved methods create smaller, more effective gelatin nanoparticles for skin delivery, and new caffeine nanocrystals enhance absorption and effectiveness.
Removing follicular plugging is crucial for effective alopecia treatment.
September 2023 in “Authorea (Authorea)” Certain peptides, caffeine, taurine, and an iron complex may improve hair regrowth when used with minoxidil and finasteride for hair loss.
August 2021 in “Institutional Repositories DataBase (IRDB)” Rubbing lotion or cream increases caffeine absorption through the skin but not rhododendrol.
Caffeine in cosmetics has antioxidant effects, protects against UV, reduces cellulite, and stimulates hair growth.
August 2015 in “Arquivo Brasileiro de Medicina Veterinária e Zootecnia/Arquivo brasileiro de medicina veterinária e zootecnia” Caffeine intake during pregnancy and lactation can cause skin lesions in mother rats and their babies, not linked to cortisol levels.
October 2014 in “Archives of disease in childhood” Childhood cancer diagnosis leads to long-term physical and emotional health issues in parents.