May 2023 in “Journal of Clinical Medicine” New understanding and treatments for hair loss are improving, but more research is needed.
October 2022 in “Frontiers in Endocrinology” New tools show that in fish, NPY increases feeding and somatostatin decreases it.
318 citations
,
January 2022 in “Signal Transduction and Targeted Therapy” The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.
249 citations
,
November 2018 in “Cell” TNFα helps grow and maintain liver cells in 3D culture for a long time.
95 citations
,
August 2013 in “Journal of Investigative Dermatology” HPT axis hormones boost mitochondrial function and growth in hair follicles, potentially aiding hair health.
68 citations
,
May 2024 in “International Journal of Molecular Sciences” Personalized acne treatments and new therapies show promise for better results.
57 citations
,
April 2009 in “Differentiation” SDF-1/CXCL12 and its receptor CXCR4 are crucial for melanocyte movement in mouse hair follicles.
45 citations
,
June 2018 in “Frontiers in immunology” MDSC-Exo can treat autoimmune alopecia areata and promote hair regrowth in mice.
29 citations
,
February 2021 in “Cancers” Ion channels play a key role in ovarian cancer growth and treatment resistance.
25 citations
,
February 2024 in “Biomaterials” Stem cell-derived organoids can improve skin healing.
21 citations
,
April 2025 in “MedComm” Alopecia areata causes unpredictable hair loss, and more research is needed to fully understand and treat it effectively.
19 citations
,
September 2006 in “Journal of Neurophysiology” Neurosteroids help balance brain signals when certain inhibitions are reduced.
18 citations
,
May 2024 in “Pharmaceutics” Improved delivery systems can enhance oleanolic acid's effectiveness in treating various conditions.
14 citations
,
April 2022 in “Climacteric” Menopause causes dry skin, wrinkles, and hair changes, with hormone therapy helping but not recommended just for these issues.
14 citations
,
January 2020 in “Frontiers in Endocrinology” OCT4 helps granulosa cell growth in early-stage follicles, and FSH increases OCT4 through specific pathways.
13 citations
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January 2023 in “Frontiers in Nutrition” Lindera aggregata has many beneficial compounds that can help prevent and manage diseases.
12 citations
,
October 2023 in “International Journal of Molecular Sciences” Understanding how skin cells react to pressure can help diagnose and manage pressure-related skin disorders.
10 citations
,
August 2023 in “Advanced Science” Nitric Oxide has potential in medicine, especially for infections and heart treatments, but its short life and delivery challenges limit its use.
6 citations
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February 2023 in “Cosmetics” Nostoc verrucosum extracts may help reduce melanin production and have antioxidant properties.
6 citations
,
October 2022 in “Frontiers in Physiology” Calcium channels are vital for normal skin function and their dysfunction can lead to skin issues.
4 citations
,
October 2021 in “Journal of Cellular and Molecular Medicine” White blood cells and their traps can slow down the process of new hair growth after a wound.
4 citations
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February 2019 in “BioMed Research International” Ebastine may promote hair regrowth by increasing cell growth through the ERK pathway.
3 citations
,
December 2024 in “International Journal of Dermatology” Premature hair graying is caused by genetics, stress, and lifestyle, and affects mental health.
2 citations
,
May 2023 in “Frontiers in Pharmacology” Natural products may help treat skin inflammation from abnormal adrenal hormones.
1 citations
,
October 2025 in “International Journal of Molecular Sciences” Natural compounds may help treat advanced papillary thyroid cancer by targeting specific molecular pathways.
1 citations
,
September 2023 in “Stem cell research & therapy” Mesenchymal stem cells could help treat aging-related diseases better than current methods.
1 citations
,
October 2022 in “Annual review of cell and developmental biology” The nervous system helps control stem cell behavior and immune responses, affecting tissue repair and maintenance.
1 citations
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May 2017 in “InTech eBooks” New treatments focusing on immune pathways show promise for stubborn hair loss.
February 2026 in “International Journal of Molecular Sciences” Extracellular vesicles show promise for medical use but face challenges in standardization and safety.
November 2025 in “Journal of Clinical Medicine” The drinkable supplement reduced hair shedding and increased hair growth in women.