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5-Bromo-3,4-Dihydroxybenzaldehyde Promotes Hair Growth Through Activation of Wnt/β-Catenin and Autophagy Pathways and Inhibition of TGF-β Pathways in Dermal Papilla Cells

research 5-Bromo-3,4-dihydroxybenzaldehyde Promotes Hair Growth through Activation of Wnt/β-Catenin and Autophagy Pathways and Inhibition of TGF-β Pathways in Dermal Papilla Cells

7 citations , March 2022 in “Molecules”

5-Bromo-3,4-dihydroxybenzaldehyde could potentially help hair growth by activating certain cell pathways and inhibiting others.

research Hair growth-promoting effect of Geranium sibiricum extract in human dermal papilla cells and C57BL/6 mice

36 citations , February 2017 in “BMC Complementary and Alternative Medicine”

Geranium sibiricum extract helps hair grow and is more effective than minoxidil but can be toxic in high concentrations.

research ERUCA SATIVA LINN.: PHARMACOGNOSTICAL AND PHARMACOLOGICAL PROPERTIES AND PHARMACEUTICAL PREPARATIONS

47 citations , February 2019 in “Asian Journal of Pharmaceutical and Clinical Research”

Jarjeer has potential health benefits and may aid hair growth, but effects on humans are uncertain.

research The effect of Cotinus coggygria L. ethanol extract in the treatment of burn wounds

10 citations , January 2022 in “Journal of Research in Pharmacy”

Cotinus coggygria extract cream may help heal burn wounds.

Highly Efficient Nucleophilic Addition of Alkyl Grignard Reagents to 17-Ketosteroids in the Presence of Cerium(III) Chloride: Synthesis of 17α-Propyl-17β-Hydroxy-4-Androsten-3-One, an Androgen Receptor Antagonist

research Highly efficient nucleophilic addition of alkyl Grignard reagents to 17-ketosteroids in the presence of cerium(III) chloride: Synthesis of 17α-propyl-17β-hydroxy-4-androsten-3-one, an androgen receptor antagonist

14 citations , February 1994 in “Tetrahedron Letters”

Adding cerium(III) chloride to Grignard reagents improves the making of compounds that could treat prostate issues and hair loss.

research Benzo[c]quinolizin-3-ones: A Novel Class of Potent and Selective Nonsteroidal Inhibitors of Human Steroid 5α-Reductase 1

28 citations , September 2000 in “Journal of Medicinal Chemistry”

Benzo[c]quinolizin-3-ones are effective nonsteroidal inhibitors of human steroid 5α-reductase 1.

research The search for bioactive compounds in tropical plants to target hormone imbalance associated diseases

2 citations , January 2007 in “edoc (University of Basel)”

Piper cubeba and Aquilaria sinensis may help prevent or treat prostate issues by balancing hormones.

research Peer Review #2 of "A novel control of human keratin expression: cannabinoid receptor 1-mediated signaling down-regulates the expression of keratins K6 and K16 in human keratinocytes in vitro and in situ (v0.1)"

February 2013

Activating CB1 can reduce keratin levels, potentially helping manage psoriasis and aid wound healing.

Formulation Development and Investigations on Therapeutic Potential of Nanogel from Beta Vulgaris L. Extract in Testosterone-Induced Alopecia

research Formulation Development and Investigations on Therapeutic Potential of Nanogel from Beta vulgaris L. Extract in Testosterone-Induced Alopecia

2 citations , January 2023 in “BioMed Research International”

Beetroot extract nanogel may help treat hair loss caused by testosterone.

research Zingiber junceum Gagnep., A New Record for the Flora of Vietnam and its Anatomical and Phytochemical Characteristics

May 2025 in “Tropical Natural History”

Zingiber junceum Gagnep. is now found in Vietnam and contains various bioactive compounds.

research Pharmacognostical standardization of bark of Thuja orientalis Linn.

1 citations , July 2017 in “Journal of Pharmacognosy and Phytochemistry”

The study concluded that standardizing Thuja orientalis bark helps in its identification and quality control.

research TAXONOMIC AND PHARMACOGNOSTIC AUTHENTICATION OF PROBLEMATIC MEDICINAL PLANTS USED AS HERBAL MEDICINE

January 2012

The research confirmed the identity and quality of seven medicinal plants, aiding in their proper use in herbal medicine.

research Pharmacological and toxicological effects of Nicotiana tabacum

11 citations , September 2022 in “World Journal of Advanced Pharmaceutical and Medical Research”

Nicotiana tabacum has potential therapeutic uses but also poses toxic risks.

Sulforaphane-Rich Broccoli Sprout Extract Promotes Hair Regrowth in an Androgenetic Alopecia Mouse Model via Enhanced Dihydrotestosterone Metabolism

research Sulforaphane-Rich Broccoli Sprout Extract Promotes Hair Regrowth in an Androgenetic Alopecia Mouse Model via Enhanced Dihydrotestosterone Metabolism

August 2025 in “International Journal of Molecular Sciences”

Broccoli sprout extract may help regrow hair by improving hormone metabolism.

research Antiandrogenic activities ofGlycyrrhiza glabrain male rats

15 citations , January 2009 in “International Journal of Andrology”

Liquorice may reduce testosterone and affect male reproductive organs, potentially helping treat conditions like prostate cancer.

research Betulinic acid exerts anti‐hepatitis C virus activity via the suppression of NF‐κB‐ and MAPK‐ERK1/2‐mediated COX‐2 expression

44 citations , June 2015 in “British Journal of Pharmacology”

Betulinic acid can help treat hepatitis C by stopping virus replication.

research PKCδ/MAPKs and NF-κB Pathways are Involved in the Regulation of Ingenane-Type Diterpenoids from Euphorbia neriifolia on Macrophage Function

9 citations , June 2021 in “Journal of Inflammation Research”

Euph E and Euri A from Euphorbia neriifolia help control inflammation and immune response in cells.

The Transcriptional Co-Activator cAMP Response Element-Binding Protein-Binding Protein Is Expressed in Prostate Cancer and Enhances Androgen- and Anti-Androgen-Induced Androgen Receptor Function

research The Transcriptional Co-Activator cAMP Response Element-Binding Protein-Binding Protein Is Expressed in Prostate Cancer and Enhances Androgen- and Anti-Androgen-Induced Androgen Receptor Function

72 citations , January 2003 in “American Journal of Pathology”

A protein called CBP is found in prostate cancer and can increase the effectiveness of certain prostate cancer treatments.

research P33 Quantification of metabolic pathways in human hair follicles and their response to caffeine and N,N-dimethylglycine

January 2026 in “British Journal of Dermatology”

Caffeine and DMG increase calcium influx in hair follicle cells without being toxic.

research Identifying the Active Components and Mechanisms of Persicae Semen in Treating Androgenetic Alopecia: Insights from Network Pharmacology and Experimental Evaluations

April 2025 in “Journal of Ethnopharmacology”

Amygdalin in Persicae Semen may help treat hair loss by promoting hair growth and regulating key pathways.

research Structure-activity relationship for calanthoside, a potential hairgrowth stimulant with an indole 2- S -,3- O -bis-glucoside structure. Part 1: Role of two glucoside moieties in promoting HFDPC proliferation

January 2026 in “RSC Medicinal Chemistry”

Calanthoside may help hair growth by boosting cell proliferation.

research Arecaceae

October 2015 in “Elsevier eBooks”

Chewing betel nut may increase the risk of type 2 diabetes, and saw palmetto can improve urinary symptoms in BPH with fewer side effects but may cause bleeding and allergic reactions.

research Mediterranean Basin Erica Species: Traditional Uses, Phytochemistry and Pharmacological Properties

4 citations , June 2025 in “Molecules”

Mediterranean Erica plants may help with inflammation, infections, and weight loss due to their bioactive compounds.

GC-MS Analysis and Phytochemical Screening of Indigofera Tinctoria Leaf Extract Characterizing Its Medicinal Use

research GC-MS Analysis and Phytochemical Screening of Indigofera tinctoria (Linn.) Leaf Extract Characterizing its Medicinal Use

11 citations , July 2020 in “International Journal of Ayurvedic Medicine”

Indigofera tinctoria leaf extract has many compounds that support its traditional medicinal uses.

research Modulation of AR-FGF-2-TGF beta Axis by Cosmos caudatus Suppresses Prostatic Epithelial Proliferation in a BPH Rat Model: A Comparative Study with Finasteride

March 2026 in “Journal of Multidisciplinary Applied Natural Science”

Cosmos caudatus extract is as effective as finasteride for treating benign prostatic hyperplasia without its side effects.

research Hair promotion effect of Beta vulgaris L. fruit extracts; physicochemical, and analytical evaluation

January 2026

Beta vulgaris L. fruit extracts, especially ethanolic, effectively promote hair growth.

research Effect of the ethanol extract of Syzygium aromaticum (clove) leaves on the lipid profile and body weight in testosterone-induced benign prostatic hyperplasia rats

May 2026 in “Global Translational Medicine”

The study examined the effects of ethanol extract of Syzygium aromaticum (clove) leaves on lipid profiles and body weight in testosterone-induced benign prostatic hyperplasia (BPH) rats. Thirty-six rats were divided into six groups, including controls and various treatment groups with clove extract and finasteride. Over 28 days, significant decreases in triacylglycerol, total cholesterol, low-density lipoprotein, and very low-density lipoprotein were observed in the clove-treated groups compared to the BPH control. High-density lipoprotein cholesterol increased significantly in the treatment groups. Additionally, body weight increased in the treatment groups. These results suggest that clove leaf extract has anti-hyperlipidemic effects and may influence body weight by enhancing metabolic activity in BPH conditions.

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