research Modeling Oxidative Stress–Linked Telogen Effluvium: A Monte Carlo Simulation Using Published Trichoscopy Norms and Cannabis Exposure Distributions
Higher cannabis exposure may worsen hair loss.
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570-600 / 1000+ results research Lysophosphatidic acid and signaling in sensory neurons
Lysophosphatidic acid affects sensory neurons and may cause neuropathic pain and itch.
research Cutaneous Atrophy and Alopecia After Greater Occipital Nerve Injection Using Triamcinolone
Triamcinolone injections for headaches can cause skin thinning and hair loss.
research High-throughput and direct measurement of androgen levels using turbulent flow chromatography liquid chromatography-triple quadrupole mass spectrometry (TFC-LC-TQMS) to discover chemicals that modulate dihydrotestosterone production in human prostate cancer cells
Researchers found four natural compounds that can change DHT levels in prostate cancer cells.
research Extracellular ATP and Adenosine Signaling in Arabidopsis: Investigating Cellular Modulation
Extracellular ATP promotes growth, while adenosine inhibits it in Arabidopsis plants.
research Targeting of Smoothened for therapeutic gain
Targeting the Smoothened receptor shows promise for treating certain cancers.
research Effective holistic characterization of small molecule effects using heterogeneous biological networks
Integrating biological networks improves drug repurposing and ADR prediction.
research C‐tactile afferents: The mystery of human emotional touch has been hidden hair‐deep
C-tactile afferents are linked to emotional touch and social bonding through hair movement.
research Molecular insights into the formation of drug-polymer inclusion complex
The research shows how certain drugs can form stable structures with polymers, which is important for making new pharmaceuticals.
research Phase-specific differential regulation of mechanical allodynia in a murine model of neuropathic pain by progesterone
Progesterone initially worsens but later reduces neuropathic pain in mice, through different mechanisms.
research Phytotherapeutic Molecules & Antioxidants: A Novel & Secure Approach of Cancer Prevention
Natural antioxidants and phytotherapeutic molecules may help prevent cancer.
research Divergent neuroactive steroid responses to stress and ethanol in rat and mouse strains: relevance for human studies
Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.
research Kosmetik Rambut menurut Ibn Sina dalam Al-Qanun fi'l-Tibb II; Komponen Kimia dan aktivitasnya - Review
Ibn Sina identified plant components useful for hair cosmetics.
research Clinical Snippets
Increased pigmentation may protect skin from UVB, new targets for skin disease treatments were identified, sunscreen ingredients don't affect hormones, TNF-α inhibitors may help diabetic wounds, and certain treatments could prevent chemotherapy-induced hair loss.
research Effect of dihydrotestosterone on the upregulation of inflammatory cytokines in cultured sebocytes
Dihydrotestosterone increases certain inflammatory signals in skin cells, potentially contributing to acne.
research Hair-Cycle-Associated Remodeling of the Peptidergic Innervation of Murine Skin, and Hair Growth Modulation by Neuropeptides
Neuropeptides affect hair growth, with some speeding it up and others slowing it down.
research New product intros (finasteride/tadalafil (new combination); sutimlimab; human SARS-CoV-2 recombinant nanoparticle vaccine, adjuvanted with AS03; bupropion hydrochloride/dextromethorphan hydrobromide (new combination))
research Cyclooxygenase-2 overexpression in the skin of transgenic mice results in suppression of tumor development.
Overexpressing COX-2 in mice skin reduces skin tumor development.
research An Intensive Study on Curcuma longa and Dalbergia sissoo as Possible Promising Combination for the Treatment of Various Ailments
Curcuma longa and Dalbergia sissoo may work well together to treat inflammation, stress, and cancer.
research O19 CYLD cutaneous syndrome tumours demonstrate increased NF-κB signalling and diminished collagen organisation.
Skin tumors with CYLD cutaneous syndrome show more NF-κB activity and less organized collagen.
research Protein Kinase C δ Overexpressing Transgenic Mice Are Resistant to Chemically but not to UV Radiation–Induced Development of Squamous Cell Carcinomas: A Possible Link to Specific Cytokines and Cyclooxygenase-2
Mice with extra PKCδ resist chemical-induced skin cancer but not UV-induced.
research Dihydroartemisinin loaded nanostructured lipid carriers (DHA-NLC): evaluation of pharmacokinetics and tissue distribution after intravenous administration to rats.
DHA-NLC may improve drug delivery and reduce side effects for cancer treatment.
research Indole Glycosides from <i>Calanthe discolor</i> with Proliferative Activity on Human Hair Follicle Dermal Papilla Cells
Extracts from the Calanthe discolor plant promote hair follicle growth and increase growth factor levels.
research Glia-derived steroids modulate epileptogenesis in a model of temporal lobe epilepsy
Neurosteroids from glia cells help control seizure development in epilepsy.
research Actos, slings, finasteride, and the vaccine compensation solution.
research Neuropeptídeos na pele
Neuropeptides affect skin inflammation, repair, and hair growth, with potential for therapy.
research Molecular studies of transient receptor potential Vanilloid 3 (TRPV3)
TRPV3 channels are involved in skin processes and are affected by shear stress, influencing itch and mechanotransduction.
research Cyclic Nucleotides and the Mediation of Melatonin-induced Inhibition of Melanogenesis in Mammals
Melatonin stops melanin production after tyrosinase action, with cyclic GMP mimicking this effect.
research Novel synthesis of nicotinamide derivatives of cytotoxic properties
Newly made nicotinamide compounds could potentially treat cancer.
research Synthesis of N-Substituted 3-Oxo-17b- carboxamide-4-aza-5a-androstanes and the Tautomerism of 3-Oxo-4-aza-5-androstenes
Researchers made two new compounds that could be used for medicine.