research Epithelial–mesenchymal transition in cutaneous fibrosis disease: from mechanisms to therapy
EMT plays a key role in skin fibrosis and offers new therapy targets.
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research Engineering immune-competent hair follicle microphysiological systems: from organoid assembly to dynamic immune modelling
Hair follicle systems are being engineered to better mimic natural hair follicles for studying hair disorders and testing treatments.
research A multi-omic single-cell landscape of perinatal mouse skin maps lineage specification and reveals shared dynamics in human fetal skin
Mouse and human skin development share similar fibroblast timelines.
research Dissecting the boundary of quiescence and activation of murine melanocyte stem cells in the hair follicle niche
Melanocyte stem cells in hair follicles are key to understanding and potentially preventing hair graying.
research Immunomodulatory roles of regulatory T cells in cutaneous wound healing: mechanisms and therapeutic opportunities
Regulatory T cells help heal skin wounds by reducing inflammation and promoting tissue repair.
research Role of skin microbiome and exosomes in Hair regeneration and disorders in diseases like Alopecia, Acne: A comprehensive review
Restoring microbial balance and using exosome therapies may help treat hair disorders like alopecia and acne.
research Caractérisation d’une modification «bigarré» de la couleur du pelage chez le chat domestique
Variegated coat color in cats is linked to the Silver locus.
research Integrated-omics profiling unveils the disparities of host defense to ECM scaffolds during wound healing in aged individuals
Aged individuals heal wounds less effectively due to specific immune cell issues.
research Molecular heterogeneity of quiescent melanocyte stem cells revealed by single-cell RNA-sequencing
Different types of inactive melanocyte stem cells exist with unique characteristics and potential to develop into other cells.
research Integrated Analysis of miRNAs and mRNA Profiling Reveals the Potential Role of miRNAs in Sheep Hair Follicle Development
Certain miRNAs may play a role in sheep hair follicle development, which could help improve wool production.
research A direct link betweenPrss53, hair curvature, and skeletal dysplasia
The gene Prss53 affects hair shape and bone development in rabbits.
research Molecular Regulation and Cellular Heterogeneity in Skin Repair and Hair Follicle Regeneration
Ovol2 is crucial for hair growth and skin healing by controlling cell movement and growth.
research Understanding the functional contribution of dermal stem cells to hair follicle regeneration and skin wound healing
Dermal stem cells help regenerate hair follicles and heal skin wounds.
research A family business: stem cell progeny join the niche to regulate homeostasis
Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.
research The Immune Functions of Keratinocytes in Skin Wound Healing
Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.
research Paneth Cells in Intestinal Homeostasis and Tissue Injury
Paneth cells help support stem cells and aid tissue regeneration after injury.
research BMP2 and BMP7 play antagonistic roles in feather induction
BMP2 and BMP7 have opposite roles in feather formation.
research The Modulatable Stem Cell Niche: Tissue Interactions during Hair and Feather Follicle Regeneration
The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.
research Strategies to enhance epithelial–mesenchymal interactions for human hair follicle bioengineering
Improving the environment and cell interactions is key for creating human hair in the lab.
research The Pharmacology of Regenerative Medicine
Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.
research Functional hair follicle regeneration: an updated review
Hair follicle regeneration possible, more research needed.
research Oxidative stress management in the hair follicle: Could targeting NRF2 counter age‐related hair disorders and beyond?
Activating NRF2 might help treat hair disorders by improving antioxidant defenses.
research Current Perspectives on the Physiological Activities of Fermented Soybean-Derived Cheonggukjang
Cheonggukjang may help prevent and manage various diseases and improve overall health, but its odor and safety concerns need addressing.
research The inconsistent regulation of HOXC13 on different keratins and the regulation mechanism on HOXC13 in cashmere goat (Capra hircus)
The HOXC13 gene affects different hair proteins in cashmere goats in varied ways and is controlled by a feedback loop and other factors.
research The concealed side of caspases: beyond a killer of cells
Caspases do more than kill cells; they also help in cell growth and disease, and targeting them could lead to new treatments.
research Demethylation of ITGAV accelerates osteogenic differentiation in a blast-induced heterotopic ossification in vitro cell culture model
Removing a methyl group from the ITGAV gene speeds up bone formation in a specific type of bone disease model.
research The pioneer factor SOX9 competes for epigenetic factors to switch stem cell fates
SOX9 helps determine stem cell roles by interacting with DNA and proteins that control gene activity.
research Abstracts from the 55th European Society of Human Genetics (ESHG) Conference: Oral Presentations
NIPT can help detect potential maternal cancer, and GIPXplore can identify immune diseases in pregnancies.
research Dermal macrophage and its potential in inducing hair follicle regeneration
Dermal macrophages might help regrow hair.
research Deciphering the cellular landscape and genetic underpinnings of fiber diameter determined by dermal papilla cells in fine-wool sheep
Dermal papilla cells are key to fine wool growth in sheep.