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MFN2 mutations cause mitochondrial problems, unusual fat distribution, and low leptin despite high body fat.

miR-3606-3p reduces skin fibrosis by blocking key signaling pathways.

Lysine carboxymethyl cysteinate (LCC) protects skin from UVB damage by activating autophagy.

High levels of the protein Flightless I worsen ulcerative colitis symptoms in mice.

Lymphotoxin-β is crucial for proper skin development in embryos.

TLR2 helps control hair growth and regeneration, and its reduction with age or obesity can impair hair growth.

Trichohyalin is modified by enzymes to form strong structures in hair cells.

Folliculotropic mycosis fungoides has unique molecular features and cell interactions that could guide targeted therapy.

Trichohyalin helps in hair and skin cell structure and function by binding calcium and linking proteins.

Li2CO3 improved skin disease in a mouse model of Focal Dermal Hypoplasia without toxicity.

The Ysc84/SH3yl1 protein family is important for cell movement and the process of taking in materials by interacting with actin and cell membranes.

Removing Ctip2 in skin cells causes skin inflammation similar to atopic dermatitis.

Retinoic acid production and signaling in hair follicles are regulated by location and timing, affecting hair growth and cycling.

ARL15 is important for fat cell development and the release of the hormone adiponectin.

Infliximab was effective in treating a scalp condition that did not respond to other treatments.

Linoleic acid and magnesium are key in alopecia areata progression, and tofacitinib can help by affecting their pathway.

A gene called Taqpep affects cat coat patterns like stripes and blotches.

Overexpressing CtBP1 in skin cells causes skin and hair problems.

Different diets change the fat composition in mouse skin, often reducing beneficial omega-3 fatty acids.

Activating TLR9 helps heal wounds and regrow hair by using specific immune cells.

Adipocytes in atopic dermatitis skin change and worsen inflammation and fibrosis.

Impaired ABCA5 activity disrupts cholesterol balance in hair follicle cells, affecting hair growth.

PAD3 plays a key role in hair and skin protein structure and may be linked to skin diseases.

Tofacitinib effectively treated a woman's complex autoimmune and autoinflammatory disorders.

Efficient enzyme function relies on specific residue interactions and structural coordination.

New therapies for Birt–Hogg–Dubé syndrome are being developed based on understanding the FLCN gene's role.

The enzyme RDH12 plays a role in vision and retinal disease, with mutations leading to early onset visual loss and blindness, but the exact disease mechanism is unclear and there are no treatments yet.

Transamidases are present in the epidermis but their exact role is unclear.

Applying linoleic acid to the skin can reverse essential fatty acid deficiency symptoms.