research LB1603 Centrosomes are required for the normal development of the skin epithelium
Centrosomes are essential for healthy skin and hair growth, and their role is different from that of cilia.
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research Wnt Signaling, Lgr5, and Stem Cells in the Intestine and Skin
Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.
research Hair follicle aging is driven by transepidermal elimination of stem cells via COL17A1 proteolysis
Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.
research Epidermal β-catenin activation remodels the dermis via paracrine signalling to distinct fibroblast lineages
Epidermal β-catenin activation changes the dermis by signaling different fibroblast types.
research Label Retaining Cells (LRCs) with Myoepithelial Characteristic from the Proximal Acinar Region Define Stem Cells in the Sweat Gland
Sweat gland stem cells help maintain glands, aid wound healing, and can regenerate skin structures.
research Bone Morphogenetic Protein Signaling Regulates Postnatal Hair Follicle Differentiation and Cycling
Blocking BMP signaling causes hair loss and disrupts hair growth cycles.
research Molecular Dissection of Mesenchymal–Epithelial Interactions in the Hair Follicle
Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.
research Epidermal Notch1 recruits RORγ+ group 3 innate lymphoid cells to orchestrate normal skin repair
Notch1 helps skin heal by attracting specific immune cells.
research 46,XY DSD due to impaired androgen production
Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.
research Rapid mechanosensitive migration and dispersal of newly divided mesenchymal cells aid their recruitment into dermal condensates
Newly divided skin cells quickly move to join skin structures due to tissue tension and specific signals.
research The human hair: from anatomy to physiology
The document concludes that hair is complex, with a detailed growth cycle, structure, and clinical importance, affecting various scientific and medical fields.
research Colon Cancer Stem Cells: Promise of Targeted Therapy
Targeting colon cancer stem cells might lead to better treatment results.
research Microtechnology-based methods for organoid models
Microtechnology methods improve organoid production for medical research.
research Paneth Cells in Intestinal Homeostasis and Tissue Injury
Paneth cells help support stem cells and aid tissue regeneration after injury.
research Human epithelial hair follicle stem cells and their progeny: Current state of knowledge, the widening gap in translational research and future challenges
We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.
research Aberrant Activation of the Hedgehog Signaling Pathway in Malignant Hematological Neoplasms
Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.
research The TOR–Auxin Connection Upstream of Root Hair Growth
High energy boosts root hair growth in plants, while low energy stops it.
research Stem Cells in Tissue Engineering
Different stem cells have benefits and challenges for tissue repair, and more research is needed to find the best types for each use.
research Fail-tests of DNA methylation clocks, and development of a noise barometer for measuring epigenetic pressure of aging and disease
Elastic Net DNA methylation clocks are inaccurate for predicting age and health status; a "noise barometer" may better indicate aging and disease.
research Hematopoietic Stem Cells: Nature and Niche Nurture
Blood stem cells are diverse, influenced by many factors, and understanding them is key for progress in regenerative medicine.
research REV7: a small but mighty regulator of genome maintenance and cancer development
REV7 is crucial for genome stability and cancer treatment, making it a potential target for therapy.
research 3D bioprinting of prefabricated artificial skin with multicomponent hydrogel for skin and hair follicle regeneration
3D bioprinting with special hydrogels can create artificial skin that heals wounds and regrows hair in mice.
research Multimodal profiling reveals site-specific adaptation and tissue residency hallmarks of γδ T cells across organs in mice
γδ T cells adapt uniquely to different tissues in mice.
research Boosting and Rescuing Epidermal Superior Population from Fresh Keratinocyte Cultures
The method increases stem-like cells for better skin regeneration.
research Epidemiology of Cosmetic Procedures: An Update for Dermatologists
Cosmetic procedures are growing rapidly, with safety and proper techniques being crucial.
research Topical Antiandrogens
Topical antiandrogens might treat skin issues like hair growth, balding, and acne, but finding effective treatments without side effects is challenging.
research A doxycycline- and light-inducible Cre recombinase mouse model for optogenetic genome editing
The DiLiCre mouse model is an effective tool for precise genome editing using light.
research CD201+ fascia progenitors choreograph injury repair
CD201+ fascia progenitors are essential for wound healing and could be targeted for treating skin conditions.
research Immunopathogenesis of Primary Cicatricial Alopecia
Hair loss in Lichen Planopilaris is caused by immune system issues damaging hair follicles and stem cells.
research Stem cells in tissues, organoids, and cancers
Stem cells are crucial for tissue growth, cancer treatment, and disease modeling, but challenges remain in clinical use.