research Stem cell-derived exosomes: emerging therapeutic opportunities for wound healing
Tiny vesicles from stem cells could be a new treatment for healing wounds.
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research Bone vs. fat: Embryonic origin of progenitors determines response to androgen in adipocytes and osteoblasts
Androgens affect bone and fat cell development differently based on the cells' embryonic origin.
research MSC-EVs and UCB-EVs promote skin wound healing and spatial transcriptome analysis
MSC-EVs and UCB-EVs improve skin wound healing and reduce scarring.
research P63 targeted deletion under the FOXN1 promoter disrupts pre-and post-natal thymus development, function and maintenance as well as induces severe hair loss
Deleting the p63 gene in certain cells causes problems in thymus development and severe hair loss in mice.
research Androgenetic alopecia, trichotrophic substances, and histologic studies of the human scalp
Minoxidil promotes hair growth but exact mechanism is unknown.
research Fabrication and characterization of epithelial scaffolds for hair follicle regeneration
Scientists created three types of structures to help regrow hair follicles, and all showed promising results for hair regeneration.
research Co-opting Developmental Signaling Pathways to Promote Wound Healing
Using developmental signaling pathways could improve adult wound healing by mimicking scarless embryonic healing.
research The CD44+ALDH+ Population of Human Keratinocytes Is Enriched for Epidermal Stem Cells with Long-Term Repopulating Ability
Certain human skin cells marked by CD44 and ALDH are rich in stem cells capable of long-term skin renewal.
research Single-cell profiling reveals a potent role of quercetin in promoting hair regeneration
Quercetin significantly helps hair growth by activating hair follicles and improving blood vessel formation around them.
research Formulation and Development of Adapalene Topical Nanohydrogel Using Different Surfactants and Cosurfactants for Antiacne Activity: In Vitro and Ex Vivo Evaluation
NH-Tween-80 is a promising stable gel for treating acne.
research Rapid formation of multicellular spheroids in double-emulsion droplets with controllable microenvironment
A new method quickly creates controllable cell clusters for tissue engineering and drug testing.
research Re-investigating the Basement Membrane Zone of Psoriatic Epidermal Lesions: Is Laminin-511 a New Player in Psoriasis Pathogenesis?
Laminin-511 may contribute to psoriasis by affecting skin cell growth and survival.
research Reconstructed human skin shows epidermal invagination towards integrated neopapillae indicating early hair follicle formation in vitro
The experiment showed that human skin grown in the lab started to form early hair structures when special cell clusters were added.
research Autophagy critically controls skin inflammation and apoptosis-induced stem cell activation
Autophagy helps control skin inflammation and cancer responses and regulates hair growth by affecting stem cell activity.
research Unexpected Autocrine Role of Vascular Endothelial Growth Factor in Squamous Cell Carcinoma
VEGF helps squamous cell carcinoma grow in ways beyond just blood vessel formation.
research Bioinspired tuning of glycol chitosan for 3D cell culture
Glycol chitosan hydrogels enable quick, safe 3D cell spheroid formation for various applications.
research Feather arrays are patterned by interacting signalling and cell density waves
Feather patterns in birds are shaped by signaling interactions and cell movements, with EDA/EDAR crucial for pattern formation.
research The Pathological Changes and Polymorphonuclear and Mast Cell Responses in the Skin of Specific Pathogen‐free Lambs Following Primary and Secondary Challenge with Orf Virus
Lambs' skin showed similar but more severe responses to a second orf virus infection, involving immune cells and new skin formation.
research Role of -catenin in Epidermal Stem Cell Expansion, Lineage Selection, and Cancer
Beta-catenin is crucial for skin cell growth, development, and cancer formation.
research <p>Dihydrotestosterone Induces Proliferation, Migration, and Invasion of Human Glioblastoma Cell Lines</p>
Dihydrotestosterone increases growth and spread of human brain cancer cells, and blocking its formation might help treat this cancer.
research Human Wharton’s Jelly Mesenchymal Stem Cells Plasticity Augments Scar-Free Skin Wound Healing with Hair Growth
Wharton’s Jelly stem cells from the umbilical cord improve skin healing and hair growth without scarring.
research Laminin 332 Is Indispensable for Homeostatic Epidermal Differentiation Programs
Laminin 332 is essential for normal skin cell behavior and structure.
research The Therapeutic Role of ADSC-EVs in Skin Regeneration
ADSC-derived extracellular vesicles show promise for skin and hair regeneration and wound healing.
research Iris germanica L. Rhizome-Derived Exosomes Ameliorated Dihydrotestosterone-Damaged Human Follicle Dermal Papilla Cells Through the Activation of Wnt/β-Catenin Pathway
Iris-exosomes may help treat hair loss by activating hair growth pathways.
research Edar Signaling in the Control of Hair Follicle Development
Edar signaling is crucial for proper hair follicle development and function.
research Fetuin-A: A Major Fetal Serum Protein that Promotes “Wound Closure” and Scarless Healing
Fetuin-A helps wounds heal without scars by promoting cell movement.
research Spatial transcriptomics of a giant pilomatricoma
The analysis of a large pilomatricoma revealed five distinct areas with different gene activity related to hair growth and tumor development.
research Dual Case Reports for Lipid Loss from Human Hair
Changing hair's surface and structure can help protect its natural oils from being washed away.
research A Raman spectroscopy investigation of the resilience of hair cuticular scales under uniaxial stress
Hair cuticles remain stable and resilient under stress due to strong protein content and crosslinking.
research Unlocking the potential of cosmetic dermal delivery with ethosomes: A comprehensive review
Ethosomes could improve how well skin treatments work, but more research is needed on their safety and stability.