research Age-Related Hair Pigment Loss
Graying hair happens due to aging and might be delayed by new treatments.
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research Topical application of synthetic melanin promotes tissue repair
Synthetic melanin applied to skin speeds up wound healing.
research Novel in vitro culture condition improves the stemness of human dermal stem/progenitor cells
New culture method keeps human skin stem cells more stem-like.
research Merkel cell carcinoma: updates in tumor biology, emerging therapies, and preclinical models
New therapies and trials are needed for Merkel cell carcinoma, a tough skin cancer.
research Follistatin promotes LIN28B-mediated supporting cell reprogramming and hair cell regeneration in the murine cochlea
Follistatin and LIN28B together improve the ability of inner ear cells in mice to regenerate into hearing cells.
research What Ages Hair?
Hair aging and loss are caused by genetics, hormones, environment, and grooming, with treatments like minoxidil effective for certain types of hair loss.
research Locally Delivered Umbilical Cord Mesenchymal Stromal Cells Reduce Chronic Inflammation in Long-Term Nonhealing Wounds: A Randomized Study
Umbilical cord cells safely improve healing in long-term nonhealing wounds better than a placebo.
research Hair Restoration in Androgenetic Alopecia: Looking Beyond Minoxidil, Finasteride and Hair Transplantation
Alternative treatments show promise for hair growth beyond traditional methods.
research MSC-EVs and UCB-EVs promote skin wound healing and spatial transcriptome analysis
MSC-EVs and UCB-EVs improve skin wound healing and reduce scarring.
research Stem Cell-Derived Extracellular Vesicles: Promising Therapeutic Opportunities for Diabetic Wound Healing
Stem cell-derived vesicles show promise for healing diabetic wounds.
research Generation of trichogenic adipose-derived stem cells by expression of three factors
Scientists made stem cells that can grow hair by adding three specific factors to them.
research Induced pluripotent stem cell–derived mesenchymal stem cells enhance acellular nerve allografts to promote peripheral nerve regeneration by facilitating angiogenesis
Stem cells improve nerve repair by enhancing blood vessel growth.
research Mechanotransductive Differentiation of Hair Follicle Stem Cells Derived from Aged Eyelid Skin into Corneal Endothelial-Like Cells
Hair follicle stem cells from aged eyelid skin can become corneal endothelial-like cells for potential eye treatments.
research Stem Cells Therapies in Basic Science and Translational Medicine: Current Status and Treatment Monitoring Strategies
Stem cell therapies show promise for treating various diseases but face challenges in clinical use and require better monitoring techniques.
research DNMT1-mediated methylation inhibits microRNA-214-3p and promotes hair follicle stem cell differentiate into adipogenic lineages
DNMT1 helps turn hair follicle stem cells into fat cells by blocking a specific microRNA.
research What ages hair?
Hair aging is inevitable, but using the right hair care products can help maintain hair health.
research MultiKano: an automatic cell type annotation tool for single-cell multi-omics data based on Kolmogorov–Arnold network and data augmentation
MultiKano accurately identifies cell types in complex data better than existing methods.
research SPRY1 Deficiency in Keratinocytes Induces Follicular Melanocyte Stem Cell Migration to the Epidermis through p53/Stem Cell Factor/C-KIT Signaling
SPRY1 deficiency in skin cells causes stem cells to move to the skin surface, leading to increased pigmentation.
research BMI1 is required for melanocyte stem cell maintenance and hair pigmentation
BMI1 is essential for preventing hair greying and maintaining hair color.
research Epigenetic orchestration of RNA m6A methylation in wound healing and post-wound events
m6A methylation is crucial for proper wound healing and tissue repair.
research Low fucosylation defines the glycocalyx of progenitor cells and melanocytes in the human limbal stem cell niche
Low fucosylation boosts stem cell growth in the eye.
research Single cell analysis of transcriptome and open chromatin reveals the dynamics of hair follicle stem cell aging
Hair follicle stem cells change states with age, affecting hair growth and aging.
research Clinical Patterns of Hair Loss in Men
The document concludes that more research is needed to understand hair loss in men and to find new treatments.
research Advanced glycation end-products inhibit mesenchymal-epidermal interaction by up-regulating proinflammatory cytokines in hair follicles
AGEs may cause hair loss by increasing inflammation in hair follicles.
research Hair aging and anti-aging
Hair ages due to various factors and treatments like minoxidil and finasteride can help, but more research and better public awareness are needed.
research Lineage Commitment of Dermal Fibroblast Progenitors is Mediated by Chromatin De-repression
Skin cell types develop when specific genes are turned on by removing certain chemical tags from DNA.
research Characterisation of CD4+ stem cells of the skin and their role in skin homeostasis and tumourigenesis
CD4+ skin cells may be precursors to basal cell carcinoma.
research Pharmacological Treatment of Alopecia
Only minoxidil and finasteride are FDA-approved for hair loss, with other treatments available but less effective or with side effects.
research Female pattern hair loss, biological ageing and the Leiden Longevity study
Women with aging signs and heart issues have higher hair loss risk, which may predict shorter lifespan and affect attractiveness.
research Clinical Perspectives on Alopecia: From Hair Follicle Biology to Advanced Therapies
Alopecia can often be managed effectively with various treatments, but early diagnosis is crucial for preventing permanent hair loss.