research Mechanical and biological properties of keratose biomaterials
Keratose, derived from human hair, is a non-toxic biomaterial good for tissue regeneration and integrates well with body tissues.
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research Wnt and Notch signaling pathway involved in wound healing by targeting c-Myc and Hes1 separately
Wnt and Notch signaling help wound healing by promoting cell growth and regulating cell differentiation.
research Chapter 6 Fetal Skin Wound Healing
Fetal skin heals without scarring due to unique cells and processes not present in adult skin healing.
research Live imaging of stem cells: answering old questions and raising new ones
Live imaging has advanced our understanding of stem cell behavior and raised new research questions.
research Mouse Hair Cycle Expression Dynamics Modeled as Coupled Mesenchymal and Epithelial Oscillators
The study concluded that hair growth in mice is regulated by a stable interaction between skin cell types, and disrupting this can cause hair loss.
research The Rotterdam Study: 2018 update on objectives, design and main results
The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.
research Adipose-Derived Stem Cell: “Treat or Trick”
Adipose-derived stem cells show promise in treatments but need more research for safety, especially in cancer.
research Dermal T cell immunity and key regulatory signaling pathways: Implications in immune-mediated alopecia and hair regeneration
Understanding T cells and signaling pathways can lead to better treatments for hair loss.
research Mir-574-3p and Mir-125a-5p in Adipose Derived Mesenchymal Stem Cell Exosomes Synergistically Target TGF-β1/Smad2 Signaling Pathway for the Treatment of Androgenic Alopecia
Two microRNAs in stem cell exosomes help treat hair loss by targeting a specific signaling pathway.
research Nerve growth factor and burn wound healing: Update of molecular interactions with skin cells
Nerve growth factor helps improve healing time and scar quality in burn wounds.
research Multi-modal skin atlas identifies a multicellular immune-stromal community associated with disrupted cornification and specific T cell expansion in atopic dermatitis
A specific group of immune and skin cells may cause chronic inflammation in atopic dermatitis.
research Traditional Chinese Medicine Shi-Bi-Man regulates lactic acid metabolism and drives hair follicle stem cell activation to promote hair regeneration
Shi-Bi-Man, a Traditional Chinese Medicine, helps grow hair by boosting lactic acid metabolism and activating hair follicle stem cells.
research Study of the interaction between self-assembling peptide and mangiferin and in vitro release of mangiferin from in situ hydrogel
RADA16-I can effectively deliver and release mangiferin, improving its solubility and bioavailability.
research Selective Androgen Receptor Modulators (SARMs) Negatively Regulate Triple-Negative Breast Cancer Growth and Epithelial:Mesenchymal Stem Cell Signaling
SARMs may be an effective treatment for a certain type of breast cancer by blocking cancer growth and spread.
research Regionalisation of the skin
Skin varies in thickness, color, and features due to complex genetic and cellular processes.
research Dynamic interplay between IL-1 and WNT pathways in regulating dermal adipocyte lineage cells during skin development and wound regeneration
IL-1 promotes fat cell growth in skin, while WNT inhibits it and encourages scar formation.
research Regulation of Receptor Binding Specificity of FGF9 by an Autoinhibitory Homodimerization
FGF9 controls which receptors it binds to through a process where two FGF9 molecules join, and changes in FGF9 can lead to incorrect receptor activation.
research An eGFP-Col4a2 mouse model reveals basement membrane dynamics underlying hair follicle morphogenesis
Basement membrane changes are crucial for hair follicle development.
research Hair follicle stem cells as a skin‐organizing signaling center during adult homeostasis
Hair follicle stem cells help maintain skin health and could improve skin replacement therapies.
research Scarless wound healing: finding the right cells and signals
The right cells and signals can potentially lead to scarless wound healing, with a mix of natural and external wound healing controllers possibly being the best way to achieve this.
research Dynamics of Hair Follicle Morphogenesis and Skin Homeostasis
Hair follicle development involves specific cells and genes, crucial for understanding severe skin diseases like harlequin ichthyosis.
research A Novel Marker of Tissue Junctions, Collagen XXII
Collagen XXII is a marker for tissue junctions, aiding in structural integrity and found in muscles, heart, skin, and arthritic joints.
research Laminin α5 in the keratinocyte basement membrane is required for epidermal–dermal intercommunication
Laminin α5 is essential for skin communication and health.
research The regenerative potential of skin and the immune system
The skin's immune system helps it regenerate and fight infections.
research Nanofiber Scaffolds as Drug Delivery Systems Promoting Wound Healing
Nanofiber scaffolds help wounds heal by delivering drugs directly to the injury site.
research Intercellular junctions in normal epidermis
Desmosomal adhesion is essential for healthy skin structure and function.
research Cells, growth factors and biomaterials used in tissue engineering for hair follicles regeneration
Advancements in tissue engineering show promise for hair follicle regeneration to treat hair loss.
research Hair Regeneration Methods Using Cells Derived from Human Hair Follicles and Challenges to Overcome
Current hair regeneration methods show promise but face challenges in maintaining cell effectiveness and creating the right environment for hair growth.
research Hydrogel-Based Skin Regeneration
Hydrogels show promise for improving skin wound healing.
research Coordinated Activation of Wnt in Epithelial and Melanocyte Stem Cells Initiates Pigmented Hair Regeneration
Wnt signaling is crucial for pigmented hair regeneration by controlling stem cell activation and differentiation.