July 2008 in “VTechWorks (Virginia Tech)” PrPC is important for neural differentiation in cattle and mouse embryonic stem cells.
721 citations
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October 2011 in “Nature” Different types of long-lasting stem cells are responsible for the growth and upkeep of the mammary gland.
November 2025 in “Journal of Pharmacy and Pharmacology” PEDF reduces oxidative damage and supports stem cells.
10 citations
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May 2019 in “Seminars in Cell & Developmental Biology” Understanding and manipulating epigenetic changes can potentially lead to human organ regeneration therapies, but more research is needed to improve these methods and minimize risks.
5 citations
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May 2021 in “EMBO journal” Cell polarity signaling controls tissue mechanics and cell fate, with complex interactions and varying pathways across species.
June 2023 in “SPIRE - Sciences Po Institutional REpository” Extracellular vesicles and androgen receptors may help identify prostate cancer resistance and reduce SARS-CoV-2 infection.
June 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” A specific molecular switch, driven by MAPK/ERK signaling, helps spiny mice heal wounds by regenerating skin instead of forming scars.
April 2019 in “Institutional Repositories DataBase (IRDB)” Patient-derived stem cell melanocytes could be a promising treatment for vitiligo.
46 citations
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December 2018 in “Genes & Development” Lung repair involves both dedicated and flexible stem cells, important for developing new treatments.
349 citations
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January 2005 in “The FASEB journal” Human skin can make serotonin and melatonin, which help protect and maintain it.
84 citations
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August 2013 in “Journal of Cellular Biochemistry” Human Wharton's jelly stem cells improve wound healing.
48 citations
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March 2007 in “The journal of investigative dermatology/Journal of investigative dermatology” Retinoic acid production and signaling in hair follicles are regulated by location and timing, affecting hair growth and cycling.
47 citations
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January 2024 in “iScience” Stress keratins are expressed less in diseased skin and are linked to differentiation, inflammation, and immunity.
37 citations
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February 2024 in “Military Medical Research” Biomaterials can help heal wounds without scars and regenerate skin features.
28 citations
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February 2019 in “Genes” Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.
9 citations
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November 2020 in “The FASEB journal” Intermediate filaments are crucial for cell differentiation and stem cell function.
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February 2014 in “General and Comparative Endocrinology” Finasteride affects frog testes by increasing testosterone, decreasing 5α-DHT, and impacting genes related to reproduction and other functions.
2 citations
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March 2014 in “Turkderm” Mesotherapy and platelet-rich plasma treatments may help with hair loss, but their safety and effectiveness are still uncertain.
2 citations
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September 2004 in “Experimental Dermatology” Desmosomal adhesion is essential for healthy skin structure and function.
March 2026 in “Akdeniz Medical Journal” Exosomes show promise for treating skin conditions and improving cosmetic skin health.
February 2024 in “Institutional Repository of the Federal Technological University of Paraná (RIUT) (Federal University of Technology – Paraná)” Photobiomodulation can influence gene and protein expression related to healing and inflammation.
November 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” Researchers identified new cell types and genes in early hair follicle development.
97 citations
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September 2016 in “Reviews in Endocrine and Metabolic Disorders” The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.
214 citations
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April 2017 in “Cell” Different small areas within hair follicles send specific signals that control what type of cells stem cells become.
64 citations
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July 2016 in “Cold Spring Harbor Perspectives in Medicine” The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.
3 citations
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July 2023 in “Frontiers in Aging” Hair follicle stem cells change states with age, affecting hair growth and aging.
February 2025 in “Biochemistry” Stem cell therapy shows promise for treating skin disorders.
December 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Different types of inactive melanocyte stem cells exist with unique characteristics and potential to develop into other cells.
January 2018 in “Stem cell biology and regenerative medicine” The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.
K15 and Id3 are important in hair follicle regeneration, with K15 increasing in early stages and Id3 responding later.