12 citations
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December 2022 in “Current Protein and Peptide Science” Thymosin β4 helps in cell activities, healing, and organ preservation, and treats hair loss and skin injuries.
9 citations
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November 2021 in “Frontiers in Cell and Developmental Biology” PBX1 helps reduce aging and cell death in hair follicle stem cells by decreasing DNA damage, not by improving DNA repair.
9 citations
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January 2017 in “Elsevier eBooks” Skin's epithelial stem cells are crucial for repair and maintenance, and understanding them could improve treatments for skin problems.
9 citations
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October 1989 in “Australian Journal of Agricultural Research” Mouse epidermal growth factor temporarily stops wool growth and causes cell changes in Merino sheep.
7 citations
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January 2024 in “Cancer Research Communications” TAp63 and NRF2 work together to manage oxidative stress, preventing premature aging and aiding skin functions.
7 citations
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December 1991 in “Annals of the New York Academy of Sciences” Dermal papillae are crucial for hair growth and maintenance.
3 citations
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March 2023 in “Life” Obesity can worsen wound healing by negatively affecting the function of stem cells in fat tissue.
2 citations
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September 2025 in “International Journal of Nanomedicine” Extracellular vesicles can help treat skin issues like wounds, hair loss, aging, and inflammation.
1 citations
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January 2018 in “Elsevier eBooks” The skin's dermal layer contains true stem cells with diverse functions and interactions that need more research to fully understand.
June 2026 in “International Science Journal” Tissue bioengineering and regenerative medicine are improving tissue restoration and recovery, with promising new therapies and personalized approaches.
April 2026 in “Frontiers in Immunology” Blocking the CXCL12–CXCR4 axis may help treat hair loss in alopecia.
April 2026 in “Skin Appendage Disorders” Exosome therapy shows promise for treating hair loss but needs more research and standardization.
November 2025 in “Journal of Pharmacy and Pharmacology” PEDF reduces oxidative damage and supports stem cells.
August 2025 in “Journal of Polymer Science” AcD scaffolds improve tissue repair and regeneration by combining stem cells with a supportive matrix.
September 2024 in “Wound Repair and Regeneration” Obesity harms skin health by causing inflammation and delayed wound healing.
March 2022 in “Research Square (Research Square)” 4-aminopyridine, a FDA-approved drug, speeds up skin wound healing and tissue regeneration.
January 2019 in “Springer eBooks” Modified HDL can better deliver drugs and genes, potentially improving treatments and reducing side effects.
January 2019 in “Institutional Repositories DataBase (IRDB)” Hair follicles and skin structures were successfully regenerated in the lab using specific cell arrangements and mechanical conditions.
January 2018 in “Clinical dermatology open access journal” Chitosan is useful in skin treatments because it helps with wound healing and cell growth.
January 2017 in “Padua@research (University of Padova)” Adult mesenchymal stem cells show promise in improving tendon, muscle, and skin healing.
January 1999 in “Birkhäuser Basel eBooks” Metallothionein likely helps in cell growth and development in wool follicles of fetal sheep.
118 citations
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August 2010 in “Developmental Cell” MIM is crucial for hair follicle formation and regeneration by controlling cilia formation and hedgehog signaling through its interaction with Cortactin and Src.
66 citations
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May 2021 in “Science Advances” Different scaffold patterns improve wound healing and immune response in mouse skin, with aligned patterns being particularly effective.
59 citations
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September 2008 in “Journal of Burn Care & Research” Nitric oxide gel helps heal skin burns faster by improving skin growth, hair regrowth, and blood vessel formation.
37 citations
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April 2011 in “Journal of Biological Chemistry” LEF1 interacts with Vitamin D Receptor, affecting hair follicle regeneration and this could be linked to hair loss conditions.
21 citations
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October 2017 in “Journal of Investigative Dermatology” The document concludes that understanding dermal papilla cells is key to improving hair regeneration treatments.
2 citations
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December 2022 in “Bio-Design and Manufacturing” A new portable microscope can effectively monitor skin wound healing in real-time.
April 2025 in “International Journal of Molecular Sciences” Iris-exosomes may help treat hair loss by activating hair growth pathways.
May 2024 in “Journal of drug delivery science and technology” Exosomes show promise for treating skin diseases and improving skin regeneration.
135 citations
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December 2013 in “Seminars in Cell & Developmental Biology” Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.