December 2016 in “University of Birmingham Institutional Research Archive (University of Birmingham)” Glucocorticoids reduce fat production in liver cells, while androgens increase it in females; manipulating certain enzymes can influence these effects.
56 citations
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October 2007 in “Journal of Biological Chemistry” Cathepsin L is essential for heart health and its absence causes heart problems and hair loss.
July 2025 in “Burns & Trauma” 3D cell spheroids can help reduce scars by delivering therapeutic vesicles.
37 citations
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February 2005 in “Journal of Investigative Dermatology” Overexpression of SSAT causes hair loss and skin issues, but reducing putrescine can help.
14 citations
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May 2019 in “Human gene therapy” MC-DNA vector-based gene therapy can temporarily treat CBS deficiency in mice.
October 2024 in “SPIRE - Sciences Po Institutional REpository” Glypicans help hair follicle stem cells differentiate by interacting with specific receptors, influencing hair growth.
11 citations
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June 2025 in “Polymers” The review discusses the development and application of polysaccharide-based niosomes as drug delivery systems, highlighting their potential for targeted and effective drug delivery while preserving healthy tissue. Niosomes, which are self-assembling vesicular nanocarriers made from cholesterol, non-ionic surfactants, and amphiphilic substances, are versatile in applications ranging from transdermal to targeted brain delivery. The review provides a comprehensive overview of recent NIO-type formulations incorporating polysaccharides and their pharmaceutical applications, including ocular, oral, nose-to-brain, pulmonary, cardiac, and transdermal delivery. It also examines the limitations and future prospects of these drug delivery systems.
4 citations
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August 2015 in “Medical Hypotheses” The conclusion suggests that the hormone ghrelin might link acid reflux to oily skin.
March 1990 in “Journal of Dermatological Science”
178 citations
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October 2001 in “Genes & Development” The mutated hairless gene causes hair loss by acting as a new type of corepressor affecting thyroid hormone receptors.