research Positively charged chitosan-dissolving microneedles promote follicular accumulation of finasteride nanocrystals to treat androgenetic alopecia
A new microneedle system effectively delivers finasteride to treat hair loss.
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research PMON325 Rare Presentation of Precocious Puberty Secondary to LH-Secreting Adenoma
An 8-year-old boy's early puberty was caused by a rare hormone-secreting brain tumor, which was successfully treated with surgery.
research Exploring Hormone Therapy Effects on Reproduction and Health in Transgender Individuals
Hormone therapy improves mental well-being in transgender individuals but requires ongoing health monitoring.
research Pharmacokinetics of Modified Slow-Release Oral Testosterone Over 9 Days in Normal Men With Experimental Hypogonadism
The new oral testosterone pill normalized testosterone levels and lowered SHBG in men with low testosterone.
research Cross-sex hormone therapy for gender dysphoria
Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.
research Sex Steroid Hormones - Impact on Reproductive Physiology
Sex steroid hormones are essential for reproductive health and overall well-being.
research Effect of Leuprolide and Dexamethasone on Hair Growth and Hormone Levels in Hirsute Women: The Relative Importance of the Ovary and the Adrenal in the Pathogenesis of Hirsutism*
The ovary mainly causes high testosterone in PCO, while the adrenal gland is the main source in IH.
research Sperm aneuploidy in infertile male patients: a systematic review of the literature
Infertile men are more likely to produce sperm with abnormal chromosome numbers, which can affect pregnancy success and embryo health.
research Isosexual Precocious Pseudopuberty Secondary to a Testosterone-Secreting Leydig Cell Testicular Tumour: True Isosexual Development Early After Surgery*
A boy's early puberty caused by a testicular tumor returned to normal after surgery.
research Connection between granulosa cell pyroptosis and oocyte endoplasmic reticulum stress in a mouse model of polycystic ovary syndrome
Reducing granulosa cell pyroptosis may improve oocyte maturation in PCOS.
research Effects of depot medroxyprogesterone acetate, the copper IUD and the levonorgestrel implant on testosterone, sex hormone binding globulin and free testosterone levels: ancillary study of the ECHO randomized clinical trial
The levonorgestrel implant increases free testosterone and lowers SHBG more than DMPA-IM and the copper IUD.
research Severe Hyperandrogenism in A Premenopausal Woman With An Imaging-Negative Leydig Cell Tumor
A woman's severe male hormone excess was caused by a small, hard-to-find ovarian tumor.
research Testosterone: The Male Sex Hormone
More research is needed to understand how testosterone is maintained in adult males.
research Bilateral ovarian steroid cell tumor in a postmenopausal woman with progressive hyperandrogenism
Surgery removed ovarian tumors, normalizing testosterone and improving symptoms.
research 212 DISTURBANCES OF REPRODUCTIVE FUNCTION IN WOMEN WITH PITUITARY ADENOMA
Women with pituitary adenomas often have reproductive issues, like irregular periods and trouble getting pregnant, but not always breast milk production without pregnancy.
research SUN-069 A 14 Year Old Female with Primary Amenorrhea
A 14-year-old girl with no menstrual period was diagnosed with Swyer Syndrome and treated for a related cancer risk.
research Leydig cell ovarian tumour: a rare cause of hyperandrogenism
Leydig cell tumors can cause high testosterone in women and are treated by removing the ovaries.
research Effects of antiandrogen therapy of cyproteron acetate on androgen effects on the skin including androgenetic alopecia in menopausal women – case report: 10 years follow up –
Cyproterone acetate therapy improved hair loss and reduced testosterone levels in a menopausal woman.
research Serum Androgen Bioactivity in Adolescence: A Longitudinal Study of Boys with Constitutional Delay of Puberty
Testosterone and letrozole treatment speeds up puberty in boys with delayed development.
research Screening of synthetic and natural product databases: Identification of novel androgens and antiandrogens
Researchers found new potential treatments for conditions related to the androgen receptor, like male hormonal contraception, by testing thousands of compounds.
research A comparative analysis of three explanatory models of mental disorder and a preferred focus of explanation
Steroid cell tumors in the ovary are rare, can produce testosterone causing symptoms, and are mainly treated with surgery.
research Testosterone Therapy in Premenopausal Women
Testosterone therapy may improve mood, well-being, and sexual function in premenopausal women, but more research is needed on its long-term safety and effectiveness.
research Hormonal control of 5.ALPHA.-reductase activity in hamster sebaceous glands.
research Leuprolide and estrogen versus oral contraceptive pills for the treatment of hirsutism: a prospective randomized study.
Leuprolide plus estrogen is more effective than oral contraceptives for reducing hirsutism.
research Differential Expression of miR-93 and miR-21 in Granulosa Cells and Follicular Fluid of Polycystic Ovary Syndrome Associating with Different Phenotypes
The study found that certain microRNAs are higher in the cells and lower in the fluid of women with a specific type of polycystic ovary syndrome, and one microRNA could potentially help diagnose the condition.
research Development of a novel, clinically-relevant model for investigating factors that stimulate human hair growth
Testosterone stimulates growth in intermediate hair follicles, but this can be blocked by cyproterone acetate.
research Clinical observation and evaluation of CGF in the treatment of androgenic alopecia
CGF treatment effectively and safely improves hair loss in androgenic alopecia patients.
research Clomiphene citrate rescue of spermatogenesis in men with infertility while remaining on finasteride: A case report
Clomiphene citrate improves fertility in men taking finasteride for hair loss.
research O-11 DIAGNOSTIC CHALLENGES IN POSTMENOPAUSAL HYPERANDROGENISM: REPORTS OF TWO CASES
Benign conditions can mimic serious ones in postmenopausal hyperandrogenism, requiring careful diagnosis.
research Receiver operating characteristic analysis of the performance of basal serum hormone profiles for the diagnosis of polycystic ovary syndrome in epidemiological studies
Low SHBG and high FAI, FT, and DHEAS levels are effective in identifying PCOS.