research Case report: A novel splice-site mutation of MTX2 gene caused mandibuloacral dysplasia progeroid syndrome: the first report from China and literature review
A new MTX2 gene mutation caused a severe genetic disorder in a young Chinese girl.
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research Identification of an osteopontin-derived peptide that binds neuropilin-1 and activates vascular cells
FOL-026 peptide can help repair blood vessels and promote growth, offering potential treatment for vascular diseases.
research Effect of Exercise Interventions on Metabolic, Reproductive and Mental Health in Overweight Women with Polycystic Ovary Syndrome
High-intensity interval training (HIIT) is better than moderate-intensity continuous training (MICT) for improving health in overweight women with PCOS.
research 190 Deficiency of the Human Cysteine Protease Inhibitor Cystatin M/E Causes Hypotrichosis and Dry Skin
Not having enough cystatin M/E protein causes less hair growth and dry skin.
research Hallmark evidence of lipopolysaccharide (LPS) tolerance in obese women with polycystic ovary syndrome (PCOS) - LPS-induced NFkB suppression in mononuclear cells (MNC) is linked to hyperandrogenism in PCOS
High levels of testosterone and anti-Müllerian hormone before pregnancy are linked to a higher risk of newborns needing intensive care.
research Cutaneous Manifestations of Sarcoidosis : Reports of Two Cases
Sarcoidosis can cause various skin issues, making diagnosis difficult.
research Ixekizumab shows efficacy and safety in patients who failed biweekly etanercept therapy: Analysis From UNCOVER-2, a phase 3 randomized clinical trial in psoriasis
Ixekizumab is effective and safe for patients who did not improve with etanercept treatment for psoriasis.
research Is lichen planus a marker for dyslipidemia and metabolic syndrome?
Lichen planus may be associated with a higher risk of metabolic syndrome.
research Delayed Puberty
A 19-year-old male with delayed puberty was successfully treated for a condition that prevents normal hormone production.
research Risk factors for prostate cancer: a case-control study investigating selected key exposures and their interactions with predisposition genes
Age, race, family history, and certain genetic factors increase prostate cancer risk.
research A case of hidradenitis suppurativa with treatment effective by finasteride
Finasteride effectively treated hidradenitis suppurativa.
research The role of integrin alphavbeta6 in impaired wound healing and hair follicle regeneration
Integrin alphavbeta6 is important for wound healing and hair growth, and blocking it may improve these processes.
research Auto-portrait as self-evaluation and follow-up of androgenetic alopecia: A case study
Auto-portraits help evaluate scalp hair.
research Mesenchymal Stem Cell Secretome: Toward Cell-Free Therapeutic Strategies in Regenerative Medicine
The secretions of mesenchymal stem cells could be used for healing without using the cells themselves.
research Sericin hydrogels promote skin wound healing with effective regeneration of hair follicles and sebaceous glands after complete loss of epidermis and dermis
Sericin hydrogels heal skin wounds well, regrowing hair and glands with less scarring.
research Design Strategies of Conductive Hydrogel for Biomedical Applications
Conductive hydrogels show promise for medical uses like healing wounds and tissue regeneration but need improvements in safety and stability.
research Hair Follicle Regeneration in Skin Grafts: Current Concepts and Future Perspectives
Hair follicle regeneration in skin grafts may be possible using stem cells and tissue engineering.
research Efficacy and Side Effects of Drugs Commonly Used for the Treatment of Lower Urinary Tract Symptoms Associated With Benign Prostatic Hyperplasia
Different drugs for prostate-related urinary symptoms work but have various side effects, and treatment should be tailored to the individual.
research Composite materials based on metal-organic frameworks loaded with effective therapeutic components for promoting wound healing
Metal-organic frameworks help heal wounds by effectively delivering medicine.
research Interpenetrating gelatin/sodium alginate hydrogel with controlled PRP lysate delivery for accelerating diabetic wound healing with reduced scarring
The hydrogel speeds up diabetic wound healing and reduces scarring.
research Association between alopecia areata and cardiovascular disease: a systematic review and meta-analysis
People with alopecia areata have a higher risk of heart disease.
research Mesenchymal stem cell-derived protein extract induces periodontal regeneration
MSC-protein helps regenerate gum tissue and bone.
research Associations between sampling characteristics, nutritional supplemental taking and the SARS-CoV-2 infection onset in a cohort of Italian nurses
Working in non-Covid-19 wards and night shifts is linked to higher infection rates among Italian nurses.
research More than 50 long-term effects of COVID-19: a systematic review and meta-analysis
COVID-19 leaves 80% of patients with long-term symptoms like fatigue and headaches.
research Historical and Current Adenosine Receptor Agonists in Preclinical and Clinical Development
The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.
research Minoxidil in severe hypertension with renal failure
Minoxidil effectively lowers blood pressure without major side effects.
research Testosterone Supplementation for Aging-Associated Sarcopenia
Testosterone supplements can increase muscle mass and strength in older men with low levels, but long-term effects and risks need more research.
research Methotrexate in the treatment of steroid-dependent asthma
Methotrexate reduced the need for steroids in asthma patients without worsening their condition.
research Platelet-Rich Plasma and Micrografts Enriched with Autologous Human Follicle Mesenchymal Stem Cells Improve Hair Re-Growth in Androgenetic Alopecia. Biomolecular Pathway Analysis and Clinical Evaluation
PRP and HF-MSCs treatment improves hair growth, thickness, and density in androgenetic alopecia.
research Long-term treatment of severe hypertension with minoxidil, propranolol and furosemide.
Minoxidil, propranolol, and furosemide effectively control severe hypertension, but may cause sodium retention.