26 citations
,
July 2023 in “International Journal of Nanomedicine” The microneedle system shows promise for non-invasive brain drug delivery.
76 citations
,
January 2022 in “Journal of Tissue Engineering” Microneedle patches could replace injections but need more development for better use in medicine.
July 2023 in “Journal of Education, Health and Sport” Fractional microneedle radiofrequency is a safe and effective skin treatment with minimal serious side effects.
January 2022 in “Journal of Cutaneous and Aesthetic Surgery” Using truncal anesthesia on the supraorbital nerve reduces pain in hair loss treatments and improves patient comfort.
17 citations
,
August 2021 in “Dermatologic surgery” Microneedling is generally safe but can cause minor, temporary side effects and requires caution for some patients.
35 citations
,
November 2024 in “Gels” Hydrogel microneedles offer a painless, effective way to treat skin disorders.
4 citations
,
December 2022 in “Infection and Drug Resistance” Fire needle therapy is an effective and better alternative to surgery for early-stage neck carbuncles.
10 citations
,
July 2021 in “Clinical Cosmetic and Investigational Dermatology” Combining transverse needling with mini-punch grafts improves vitiligo repigmentation effectively.
September 2024 in “Journal of Cosmetic Dermatology” Cold gel compresses are the best for pain relief during scalp microneedling.
3 citations
,
May 2025 in “Lasers in Surgery and Medicine” Microneedle radiofrequency helps skin repair and rejuvenate by activating fibroblasts and remodeling the skin's structure.
3 citations
,
November 2022 in “Facial plastic surgery & aesthetic medicine” Using ultrasound to guide temple filler injections improves safety and accuracy.
June 2025 in “Archives of Dermatological Research” 55 citations
,
March 2018 in “Journal of pharmacy & pharmaceutical sciences” Microneedles help improve drug delivery through the skin and are used in medicine and beauty treatments.
28 citations
,
February 2021 in “Dermatologic Surgery” Radiofrequency microneedling is an effective and safe treatment for various skin conditions and works well with other treatments and on darker skin.
2 citations
,
July 2023 in “Journal of Education Health and Sport” Mesotherapy can cause bruises, swelling, and serious complications, so awareness and careful practice are important.
April 2016 in “Journal of Investigative Dermatology” Microneedle arrays deliver botulinum toxin effectively for sweat suppression, similar to injections.
5 citations
,
March 2019 in “Journal of The American Academy of Dermatology” Microneedling improves hair growth in androgenetic alopecia when combined with minoxidil.
2 citations
,
September 2022 in “Dermatologic therapy” Microneedling helps reduce hair-pulling and promotes hair regrowth in trichotillomania patients.
4 citations
,
May 2019 in “Journal of Cosmetic Dermatology” Using a smaller syringe causes less pain when giving an injection.
Microneedling may improve neck scars, but more research is needed.
17 citations
,
February 2023 in “Cosmetics” 3D printed hollow microneedles could effectively treat skin wrinkles with fewer side effects.
October 2025 in “Pharmaceutics” Microneedles improve drug delivery for skin diseases, enhancing treatment effectiveness and patient compliance.
6 citations
,
July 2017 in “Plastic surgical nursing : official journal of the American Society of Plastic and Reconstructive Surgical Nurses” Microneedling is effective for skin rejuvenation and various skin issues, but more research is needed to confirm its safety and effectiveness.
12 citations
,
April 2025 in “Discover Pharmaceutical Sciences” Microneedle patches offer painless, effective drug delivery and are suitable for all ages.
December 2022 in “Физиотерапия, бальнеология и реабилитация” Radiofrequency micro needling is effective for rejuvenating skin and reducing wrinkles.
20 citations
,
October 2023 in “Small” Microneedles show promise for treating hair loss, eye, and mouth diseases.
15 citations
,
January 2024 in “Chemical Engineering Journal” September 2025 in “Journal of Cosmetic Dermatology” Single-needle radiofrequency is effective and safe for treating facial sebaceous hyperplasia.
64 citations
,
May 2019 in “Materials Science and Engineering: C” Microneedle technology has improved drug delivery and patient comfort but needs more research for broader use.
1 citations
,
December 2012 in “Journal of Dermatological Treatment” Injecting triamcinolone acetonide near surgical cuts doesn't greatly affect wound healing but may help in areas with less tension.