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Testosterone increases hair growth and acne in transgender men.

Transgender women have similar fitness to cisgender women, while transgender men have higher fat and lower strength than cisgender men; hormone therapy affects body composition and strength.

Gender-affirming hormone therapy improves physical performance in trans men to the level of cisgender men, while in trans women, it increases fat mass and decreases muscle mass, with no advantage in physical performance after 2 years.

Social rejection can harm long-term mental health in transgender individuals.

Testosterone treatment may affect heart response to stress in transgender men.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

Testosterone therapy for transmasculine individuals is generally safe with medical supervision, improves mental health, and has mixed effects on physical health.

Gender-affirming hormone therapy improves mental health and gender incongruence but requires careful management of cardiovascular and cancer risks.

Transgender patients on masculinizing hormones have higher hair loss rates than cisgender women.

Hormone therapy may increase migraines in transgender women and decrease them in transgender men; more research is needed on migraine management in transgender individuals.

Hormone therapy increases the risk of heart-related issues in transgender women and may affect heart health in transgender men.

Gender-diverse people face more depression and anxiety, partly due to stress and lower cortisol levels.

Gender-diverse individuals face more depression and anxiety, possibly due to unique stress profiles.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

5α-reductase inhibitors like finasteride may not be effective or safe for transgender individuals, and more research is needed.

Men use cosmetic surgery to feel and look better, often influenced by traditional masculinity ideals.

Testosterone therapy and surgeries like mastectomy improve transgender men's lives and mental health with low risks and high satisfaction.

Testosterone pellets might work for transgender men's hormone therapy, but more research is needed.

Gender-affirming hormone therapy affects health risks and requires careful management, especially as transgender individuals age.

Early medical support for transgender youth is important for their health, with low regret for gender-affirming hormone use and a need for knowledgeable care providers.

Hormone therapy affects cancer risks in transgender individuals differently than in cisgender people, and more research is needed to understand these risks and improve cancer screening guidelines.

Hormone therapy improves mental well-being in transgender individuals but requires ongoing health monitoring.

The guideline emphasizes a multidisciplinary approach and informed consent for gender-affirming hormone treatment, with regular follow-ups and individualized care.

Research on transgender men needs clearer theories to improve understanding and decision-making.

Finasteride effectively treats hair loss in transgender men with few side effects.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Hormone therapy increases facial and body hair in transgender men, while hair removal improves well-being in transgender women, but cost is a barrier as insurance often doesn't cover it. Dermatologists can use various treatments for these hair issues.

Testosterone treatment in transgender teens can worsen acne, requiring careful treatment due to mental health and medication side effects.

Transgender men need personalized cancer care and continued testosterone therapy for well-being.

Late diagnosis of congenital adrenal hyperplasia can greatly affect physical development, gender identity, and sexual health.