research Survival of patchwork melanoblasts is dependent upon their number in the hair follicle at the end of embryogenesis
More melanoblasts in hair follicles mean better survival and proper hair pigmentation.
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810-840 / 1000+ resultsresearch Differential epithelial outgrowth of plucked and microdissected human hair follicles in explant culture
research Evo Devo of the Vertebrates Integument
The skin systems of jawed vertebrates evolved diverse appendages like hair and scales from a common structure over 420 million years ago.
research Hair Follicle Stem Cells and Hair Regeneration
research Regulation and dysregulation of hair regeneration: aiming for clinical application
Understanding hair growth involves complex factors, and more research is needed to improve treatments for hair loss conditions.
research Novel tissue mechanics-guided cellular flows drive the formation of feather follicles
Feather follicles form through specific cellular flows and mechanical changes in the skin.
research Retinoic-Acid-Related Orphan Receptor Alpha Is Involved in the Regulation of the Cytoskeleton of Hair Follicle Stem Cells
RORA affects hair follicle stem cells' structure and movement, potentially helping treat hair loss.
research Directing Rat Hair Follicle Stem Cells Toward Neuronal Lineage With Enhanced Trophic Factor Expression
Chick embryo extract helps rat hair follicle stem cells become more like neurons.
research Hair Follicle Stem Cells and Hair Regeneration
research Expression of Langerhans cell antigens in the hair follicles in alopecia areata
research Spatial and Single-Cell Transcriptional Profiling Identifies Functionally Distinct Human Dermal Fibroblast Subpopulations
Researchers found four distinct fibroblast types in human skin, which could help in treating wounds and fibrotic diseases.
research The microbiome in patients with atopic dermatitis
People with atopic dermatitis have different skin bacteria, and targeting these bacteria might help treat the condition.
research Understanding, recognizing, and managing toxicities of targeted anticancer therapies
Targeted anticancer therapies can cause severe side effects similar to traditional chemotherapy, but with different types.
research Dermal fibroblast in cutaneous development and healing
Skin cells called dermal fibroblasts are important for skin growth, hair growth, and wound healing.
research In Human Skin, UVB Initiates Early Induction of IL-10 Over IL-12 Preferentially in the Expanding Dermal Monocytic/Macrophagic Population
UVB exposure in human skin causes macrophages to produce more IL-10 and less IL-12, leading to immunosuppression.
research Neural Potential of a Stem Cell Population in the Hair Follicle
Stem cells in hair follicles can become various cell types, including neurons.
research Autoimmune Disease Induction in a Healthy Human Organ: A Humanized Mouse Model of Alopecia Areata
Alopecia areata can be triggered by specific immune cells without genetic or environmental factors.
research Spermidine Promotes Human Hair Growth and Is a Novel Modulator of Human Epithelial Stem Cell Functions
Spermidine may help reduce hair loss and deserves further testing as a treatment.
research Alopecia areata: What’s new in epidemiology, pathogenesis, diagnosis, and therapeutic options?
New insights into the causes and treatments for the autoimmune hair loss condition Alopecia areata have been made.
research Progenitor Cell Dysfunctions Underlie Some Diabetic Complications
Diabetes causes lasting cell dysfunctions, leading to serious complications even after blood sugar is controlled.
research Effects of microenvironment and biological behavior on the paracrine function of stem cells
Mesenchymal stem cells release substances that help tissue repair, and their effectiveness can be improved by understanding environmental influences.
research Diagnostic, Therapeutic, and Theranostic Multifunctional Microneedles
Microneedles are becoming essential tools in medicine for sensing, drug delivery, and communication.
research Hair follicle stem cell replication stress drives IFI16/STING-dependent inflammation in hidradenitis suppurativa
Stress in hair follicle stem cells causes inflammation in a chronic skin condition through a specific immune response pathway.
research Novel Mutations in X-Linked Dominant Chondrodysplasia Punctata (CDPX2)
New mutations in the EBP gene cause CDPX2, affecting bones, skin, eyes, and hair, with females generally less affected than males.
research Cancer risk in patients with alopecia areata: a nationwide population‐based matched cohort study
Alopecia areata patients have varied cancer risks, with some cancers being lower and others higher.
research Basal cell carcinomas acquire secondary mutations to overcome dormancy and progress from microscopic to macroscopic disease
Basal cell carcinomas need extra mutations to grow from small to large tumors.
research LGR5 is a conserved marker of hair follicle stem cells in multiple species and is present early and throughout follicle morphogenesis
LGR5 is a common marker of hair follicle stem cells in different animals and is important for hair growth and regeneration.
research From hair to pancreas: transplanted hair follicle mesenchymal stem cells express pancreatic progenitor cell markers in a rat model of acute pancreatitis.
Hair follicle stem cells may help treat acute pancreatitis by reducing inflammation and aiding regeneration.
research Hair follicle-derived mesenchymal cells support undifferentiated growth of embryonic stem cells
Hair follicle cells can help keep embryonic stem cells undifferentiated.
research Exploring Mast Cell–CD8 T Cell Interactions in Inflammatory Skin Diseases
Mast cells and CD8 T cells interact closely in skin diseases, affecting each other's behavior and contributing to conditions like psoriasis and eczema.