June 2025 in “Dermatopathology” Dupilumab and COVID-19 can worsen or trigger psoriasis.
January 2025 in “Stem Cells International” Epigenetic changes in skin cells contribute to aging, but targeting these changes may offer new antiaging treatments.
June 2023 in “Frontiers in Bioengineering and Biotechnology” The conclusion is that accurately replicating the complexity of the extracellular matrix in the lab is crucial for creating realistic human tissue models.
228 citations
,
June 2021 in “Frontiers in Immunology” Macrophage issues cause chronic wound inflammation, but therapies can help.
81 citations
,
February 2016 in “Veterinary pathology” Progeroid mouse models show signs of early aging similar to humans, helping us understand aging better.
2 citations
,
November 2025 in “International Journal of Molecular Sciences” Balancing good and harmful microbes is key to healing chronic wounds.
2 citations
,
October 2023 in “Biology” Cobalt is important for health but too much or too little can cause health problems, and its environmental buildup is a concern.
February 2026 in “Cosmetics” Fenugreek is a promising cosmetic ingredient for skin and hair care.
20 citations
,
November 2014 in “Developmental Dynamics” Palate formation and skin healing share similar biological processes.
353 citations
,
February 2022 in “Nature Immunology” Long-haul COVID can cause lasting symptoms affecting many body systems and may be linked to ongoing inflammation and immune system issues.
318 citations
,
January 2022 in “Signal Transduction and Targeted Therapy” The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.
288 citations
,
January 2001 in “Journal of Biological Chemistry” Tgm2 helps stabilize dying cells and aids fibroblast attachment to the extracellular matrix.
154 citations
,
November 2017 in “Development” Fibroblast Growth Factors (FGFs) are important for tissue repair and regeneration, influencing cell behavior and other factors involved in healing, and are crucial in processes like wound healing, bone repair, and hair growth.
146 citations
,
September 2013 in “Advances in nutrition” Bariatric surgery can cause serious mineral deficiencies, requiring better patient education and monitoring.
142 citations
,
March 2019 in “Molecules/Molecules online/Molecules annual” Cannabinoids may help treat various skin conditions.
119 citations
,
August 2010 in “Journal of Investigative Dermatology” Increased 11β-HSD1 activity in skin may contribute to aging and could be targeted to reduce aging effects.
114 citations
,
February 2023 in “International Journal of Molecular Sciences” The skin microbiome is crucial for skin health, and more research is needed to explore its role and potential treatments.
97 citations
,
December 2021 in “Cells” Designing effective fluorescence microscopy experiments requires careful consideration of hardware, biological models, and imaging agents.
96 citations
,
September 2021 in “International Journal of Molecular Sciences” Chitosan, a natural substance, can be used to create tiny particles that effectively deliver various types of drugs, but more work is needed to improve stability and control of drug release.
84 citations
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February 2015 in “Experimental Dermatology” PPARγ is crucial for skin health but can have both beneficial and harmful effects.
83 citations
,
August 2020 in “Resources” Macroalgae compounds offer sustainable, effective benefits for cosmetics.
82 citations
,
May 2020 in “International Journal of Molecular Sciences” Injectable biomaterials can effectively regenerate dental tissues.
80 citations
,
April 2006 in “Clinical Interventions in Aging” Minoxidil and Finasteride are effective for male baldness; more research is needed for hair aging treatments.
72 citations
,
June 2019 in “International Journal of Cosmetic Science” 18β-glycyrrhetinic acid from licorice root is good for skin and hair treatments but has absorption challenges.
70 citations
,
June 2023 in “International Journal of Molecular Sciences” Air pollution harms skin health and can worsen skin diseases.
70 citations
,
April 2020 in “Journal of Molecular Cell Biology” Organoid technology helps create mini-organs for studying diseases and testing drugs.
68 citations
,
May 2024 in “International Journal of Molecular Sciences” Personalized acne treatments and new therapies show promise for better results.
65 citations
,
March 2022 in “Molecules” Nanocarriers can enhance cosmetics but face regulatory and safety challenges.
60 citations
,
December 2020 in “Stem Cell Research & Therapy” ASC-CM is more effective than EV for treating osteoarthritis.
54 citations
,
January 2023 in “Signal Transduction and Targeted Therapy” New therapies are being developed that target integrin pathways to treat various diseases.