research Editor's Picks February 2021
Alopecia areata is linked to more chronic illnesses, a specific lamp helps with notalgia paresthetica itch, pycnogenol aids melasma treatment, and dupilumab improves severe atopic dermatitis in children.
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750-780 / 1000+ resultsresearch The study of improvement of hair follicle stem cells of rats in vitro culture identification and differentiation
Rat hair follicle stem cells can be effectively isolated and used for tissue engineering.
research The efficacy and particular side effects of therapy peginterferon alpha-2a acute hepatitis C hemodialysed patients
Peginterferon alpha-2a effectively treats acute hepatitis C in hemodialysed patients, despite some side effects.
research Erectile dysfunction from mechanisms to medicines with a focus on the application of topical Minoxidil
research Late-Onset Systemic Lupus Erythematosus
Older adults diagnosed with lupus show less severe symptoms but have a lower survival rate, often due to age-related factors.
research Comprehensive transcriptome and methylome analysis delineates the biological basis of hair follicle development and wool-related traits in Merino sheep
Key genes and factors crucial for hair follicle development and wool traits in Merino sheep were identified.
research Challenges in the Physical Characterization of Lipid Nanoparticles
Characterizing lipid nanoparticles is challenging due to issues with sensitivity, reproducibility, and reliability.
research Evolution of hard proteins in the sauropsid integument in relation to the cornification of skin derivatives in amniotes
Hard skin features like scales, feathers, and hair evolved through specific protein changes in different animal groups.
research Design and fabrication of customizable microneedles enabled by 3D printing for biomedical applications
3D-printed microneedles improve drug delivery and diagnostics but face scalability and regulatory challenges.
research Evaluation of an eucalyptus oil containing topical drug delivery system for selected steroid hormones
The eucalyptus oil system improved skin delivery of hormones, but safety concerns remain.
research Early breast development in girls after prenatal exposure to non‐persistent pesticides
Prenatal pesticide exposure may cause earlier breast development in girls.
research Goat Genomic Resources: The Search for Genes Associated with Its Economic Traits
Identifying specific genes helps improve goat breeding for better traits like growth and milk production.
research Mutations in SNRPE, which Encodes a Core Protein of the Spliceosome, Cause Autosomal-Dominant Hypotrichosis Simplex
Mutations in the SNRPE gene cause hereditary hair loss.
research Alkaline ceramidase 1 is essential for mammalian skin homeostasis and regulating whole‐body energy expenditure
Alkaline ceramidase 1 is crucial for healthy skin and energy balance.
research Keratins 6, 16, and 17 in Health and Disease: A Summary of Recent Findings
Keratins 6, 16, and 17 increase in damaged or diseased skin and may help diagnose skin issues.
research Determination of cortisone and cortisol in human scalp hair using an improved LC-MS/MS-based method
Cortisone in hair is a more reliable indicator of stress hormone exposure than cortisol.
research Hereditary 1,25‐Dihydroxyvitamin D‐Resistant Rickets in a Pomeranian Dog Caused by a Novel Mutation in the Vitamin D Receptor Gene
A Pomeranian dog had rickets due to a new gene mutation, leading to severe symptoms and euthanasia.
research Identification of Ovine KRTAP28-1 and Its Association with Wool Fibre Diameter
KRTAP28-1 gene can help breed sheep with finer wool.
research Characterisation of an Ovine Keratin Associated Protein (KAP) Gene, Which Would Produce a Protein Rich in Glycine and Tyrosine, but Lacking in Cysteine
A new sheep gene, KRTAP36-1, may help breed sheep with better wool by reducing prickle factor.
research Genetic and molecular aspects of androgenetic alopecia
Androgenetic alopecia is mainly caused by genetic factors and increased androgen activity, leading to hair follicle miniaturization.
research A mouse model of vitiligo based on endogenous auto-reactive CD8 + T cell targeting skin melanocyte
A new mouse model effectively mimics vitiligo for research and drug testing.
research Hair shaft miniaturization causes stem cell depletion through mechanosensory signals mediated by a Piezo1-calcium-TNF-α axis
Hair thinning causes stem cell loss through a process involving Piezo1, calcium, and TNF-α.
research Transcriptome-based selection and validation of optimal house-keeping genes for skin research in goats (Capra hircus)
NCBP3, SDHA, and PTPRA are the best genes for accurate goat skin research.
research Molecular interactions of progesterone derivatives with 5α-reductase types 1 and 2 and androgen receptors
Certain progesterone derivatives can inhibit enzymes and reduce androgenic activity, potentially affecting prostate growth.
research Skin cancer: understanding the journey of transformation from conventional to advanced treatment approaches
New treatments like nanotechnology show promise in improving skin cancer therapy.
research Novel C-6 substituted and unsubstituted pregnane derivatives as 5α-reductase inhibitors and their effect on hamster flank organs diameter size
Certain compounds reduced hamster flank organ size by inhibiting 5α-reductase, like finasteride, without affecting androgen receptors.
research New ester derivatives of dehydroepiandrosterone as 5α-reductase inhibitors
New compounds may help treat prostate issues without affecting androgen receptors.
research De NovoTranscriptome Assembly and Differential Gene Expression Profiling of ThreeCapra hircusSkin Types during Anagen of the Hair Growth Cycle
The study identified key genes involved in goat hair growth.
research Secondary Metabolites with Antifungal Activities from Mangrove Derived Fungus Monascus purpureus WMD2424
Compounds from Monascus purpureus showed mild antifungal effects.
research Exosomes derived from umbilical cord mesenchymal stem cells promote healing of complex perianal fistulas in rats
Exosomes from umbilical cord stem cells help heal complex perianal fistulas in rats.