3 citations
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April 2019 in “Stem cells international” Markers CRABP1, Nestin, and Ephrin B2 are present in skin cancer environments and may influence their development.
31 citations
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December 1991 in “Annals of the New York Academy of Sciences” ORS and hair matrix cells balance growth and differentiation better than normal keratinocytes, with human dermal fibroblasts crucial for proper differentiation.
April 2017 in “Journal of Investigative Dermatology” Early and late matrix progenitors in hair follicles create different cell layers, with early ones forming the companion layer and later ones forming the inner root sheath and hair shaft.
January 2011 in “The Chinese Journal of Dermatovenereology” DPC-hTERT cells can create hair follicle-like structures.
2 citations
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November 2003 in “Humana Press eBooks” Hair follicle cells can help heal wounds and study skin diseases.
December 2004 in “Reproduction Fertility and Development” Porcine hair follicles are useful for studying keratinocyte function, with galectin-1 as a potential stem cell marker.
3 citations
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September 2019 in “Clinical and experimental dermatology” Basal cell carcinomas may differentiate similarly to hair follicles and could be influenced by hair cycle-related treatments.
375 citations
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June 2013 in “Biochimica et biophysica acta. Molecular cell research” Cornification is how skin cells die to form the protective outer layer of skin, hair, and nails.
March 1995 in “The Journal of Dermatology” Immature hair cells can grow and change into different types of hair cells over time.
29 citations
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January 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” P-cadherin is crucial for hair follicle pigmentation but not skin pigmentation.
April 2023 in “Journal of Investigative Dermatology” Aging changes skin cells, leading to different DNA methylation and gene activity, affecting cell metabolism and aging signs.
83 citations
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February 1991 in “Development” Fos protein is crucial for cell transition to cornification in keratinized tissues.
190 citations
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October 2002 in “The FASEB journal” Androgens may cause hair loss by increasing TGF-beta1 from scalp cells, which inhibits hair cell growth.
133 citations
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March 1999 in “Journal of Cutaneous Pathology” Trichoepitheliomas and some basal cell carcinomas likely come from hair follicle stem cells.
30 citations
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November 2020 in “Journal of Advanced Research” Conditioned medium from keratinocytes can improve hair growth potential in cultured dermal papilla cells.
40 citations
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June 2013 in “Biomaterials” Scientists created 3D hair-like structures that could help study hair growth and test treatments.
June 2023 in “Zenodo (CERN European Organization for Nuclear Research)” Inflammation in hair follicles is a key risk factor for developing common baldness.
29 citations
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July 2014 in “PloS one” Meis1 is crucial for skin health and tumor development.
30 citations
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July 1998 in “British Journal of Dermatology” Fat cells slow hair cell growth but speed up their development.
6 citations
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December 2013 in “Journal of Cutaneous Pathology” Certain immune cells are more common on the top of the head and might help predict or treat common hair loss.
June 2020 in “Journal of Investigative Dermatology” Scientists successfully grew mini hair follicles using human skin cells, which could help treat baldness.
1 citations
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May 2023 in “PubMed” A certain type of skin cell, marked by EGFR, produces a lot of IGF1 and helps hair follicles grow back faster.
February 2011 in “Journal of Investigative Dermatology” New findings suggest targeting IL-23 could treat psoriasis, skin cells can adapt to new roles, direct conversion of skin cells to blood cells may aid cell therapy, removing certain tumor cells could boost cancer immunotherapy, and melanoma may have many tumorigenic cells, not just cancer stem cells.
August 2013 in “International Wound Journal” Non-hairy skin cells might be used to regenerate hair, helping with baldness and skin wounds.
2 citations
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March 2018 in “Biotechnology Letters” Scientists created a new cell line from Cashmere goat hair and found that cytokeratin 13 is a unique marker for certain skin cells.
January 2012 in “Institutional Repositories DataBase (IRDB)” Cells from skin and lung can help regenerate hair follicles.
11 citations
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October 2018 in “The Journal of Dermatology” Decorin helps keep hair follicle stem cells and may prevent age-related hair loss.
19 citations
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September 2007 in “The Journal of Steroid Biochemistry and Molecular Biology” Glucocorticoid receptors help regulate genes important for skin health and hair growth.
27 citations
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August 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” Researchers found new genes involved in hair growth, which could help develop new hair treatments.
January 2008 in “Yearbook of Dermatology and Dermatologic Surgery” One type of progenitor cell can maintain normal skin in mice.