research Classification Framework for Healthy Hairs and Alopecia Areata: A Machine Learning (ML) Approach
Machine learning can accurately identify Alopecia Areata, aiding in early detection and treatment of this hair loss condition.
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research A Guide to Studying Human Hair Follicle Cycling In Vivo
The document provides a method to classify human hair growth stages using a model with human scalp on mice, aiming to standardize hair research.
research Mathematical model for alopecia areata
The model showed that immune system guardians and the cytokine interferon-γ are key in alopecia areata progression.
research From basic biology to engineered therapies: the keratinocyte stem cell playbook
Keratinocyte stem cells are crucial for skin renewal and have potential in wound healing and tissue regeneration.
research Single Root hair growth under constant force: insights into wall mechanics
Root hair growth slows under force, confirming a model of cell wall mechanics.
research Application of multi-omics techniques to androgenetic alopecia: Current status and perspectives
Multi-omics techniques help understand the molecular causes of androgenetic alopecia.
research Computational drug discovery of potential 5α-reductase phytochemical inhibitors and hair growth promotion using in silico techniques
Jamogenin from plants may help hair growth and is a potential alternative to finasteride.
research A Composite Model for the Transport of Hydrophilic and Lipophilic Compounds Across the Skin: Steady-State Behavior
The model better predicts how water-loving and fat-loving substances move through the skin by including tiny pores and hair follicle paths.
research Ectodysplasin research—Where to next?
Future research on ectodysplasin should explore its role in diseases, stem cells, and evolution, and continue developing treatments for genetic disorders like hypohidrotic ectodermal dysplasia.
research Novel Lead Generation through Hypothetical Pharmacophore Three-Dimensional Database Searching: Discovery of Isoflavonoids as Nonsteroidal Inhibitors of Rat 5α-Reductase
Researchers found new potential but less potent rat enzyme inhibitors using a 3D model.
research Exploring pericyte and cardiac stem cell secretome unveils new tactics for drug discovery
New drugs for heart disease may be developed from molecules secreted by stem cells.
research Solubility of minoxidil in binary mixture of ethanol + water at various temperatures
Minoxidil dissolves better in ethanol-water mixtures at different temperatures, with water playing a key role.
research Analysing the dynamics of a model for alopecia areata as an autoimmune disorder of hair follicle cycling
The model helps understand and improve treatments for alopecia areata by simulating hair growth and immune cell interactions.
research Harnessing the Biomimetic Effect of Macromolecular Crowding in the Cell-Derived Model of Clubfoot Fibrosis
The model helps test drugs for clubfoot fibrosis by mimicking cell environments and shows minoxidil reduces harmful collagen links.
research A general mathematical model for the in vitro assembly dynamics of intermediate filament proteins
The model shows that filament flexibility and amino acid differences affect how fast intermediate filament proteins assemble.
research Incidence of alopecia in brain tumour patients treated with pencil scanning proton therapy and validation of existing NTCP models
A standardized scoring system is needed to improve model reliability for predicting hair loss in brain tumor patients treated with proton therapy.
research Computational Drug Discovery in Chemotherapy-induced Alopecia via Text Mining and Biomedical Databases
Computational tools identified 29 drugs that could potentially target 19 genes involved in chemotherapy-induced hair loss, which could lead to more effective treatments.
research Sequence and structure based assessment of non-synonymous SNPs in hypertrichosis universalis
Two specific SNPs in the TRPS1 gene cause excessive hair growth by altering the protein's structure.
research Pharmacophore and Atom Based 3D QSAR Studies on the Novel 5-Alpha-Reductase Inhibitors
The developed model can predict effective 5-alpha-reductase enzyme inhibitors.
research Application of big data analytics in minoxidil drug development: a data-driven model for predicting efficacy and side effect risks
The model predicts minoxidil's effectiveness and side effects better than traditional methods.
research Computational Drug Repositioning in Cardiorenal Disease: Opportunities, Challenges, and Approaches
Drug repositioning is a promising way to quickly develop new treatments, especially for rare diseases.
research Ovarian morphology is associated with insulin resistance in women with polycystic ovary syndrome: a cross sectional study
Larger ovarian size is linked to higher insulin resistance in women with PCOS.
research Elevated fasting insulin is associated with cardiovascular and metabolic risk in women with polycystic ovary syndrome
High fasting insulin levels in women with PCOS are linked to a higher risk of heart and metabolic problems.
research Establishment of an in vitro hairless guinea pig dermal model
Researchers developed a cost-effective, ethical skin model using hairless guinea pig cells for toxicology studies.
research Research Progress on Construction Technology of 3D Human Skin Models and Its Application Prospects in Dermatology
3D human skin models show promise for dermatology but face challenges in standardization and cost.
research The role of 3Rs in the age of One Health: where we are and where we’re going
Innovative methods are reducing animal testing and improving biomedical research.
research Penetration of drugs through skin, a complex rate-controlling membrane
The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.
research Deep Clustering via Center-Oriented Margin Free-Triplet Loss for Skin Lesion Detection in Highly Imbalanced Datasets
The new method improves skin cancer detection in imbalanced datasets.
research Signalling by senescent melanocytes hyperactivates hair growth
Senescent melanocytes can boost hair growth by activating hair stem cells.
research Deciphering principles of morphogenesis from temporal and spatial patterns on the integument
The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.