Search

for
Search:

Did you mean Confocal Microscopy?

GlossaryConfocal Microscopy

uses laser light to create detailed, three-dimensional images

Confocal Microscopy, also known as Confocal Laser Scanning Microscopy (CLSM), is an advanced imaging technique that uses laser light to scan samples and create high-resolution, three-dimensional images. By focusing on a specific plane within the sample and excluding out-of-focus light, it provides clearer and more detailed images than traditional microscopy, making it particularly useful for studying complex structures like hair follicles and skin tissues in both research and medical diagnostics.

Related Terms

Sort by

Research

30 / 1000+ results

research Characterization and quantification of wound-induced hair follicle neogenesis using in vivo confocal scanning laser microscopy

26 citations , April 2011 in “Skin Research and Technology”

In vivo confocal scanning laser microscopy is an effective, non-invasive way to study and measure new hair growth after skin injury in mice.

Hair Regrowth Boosting Via Minoxidil Cubosomes: Formulation Development, In Vivo Hair Regrowth Evaluation, Histopathological Examination, and Confocal Laser Microscopy Imaging

research Hair regrowth boosting via minoxidil cubosomes: Formulation development, in vivo hair regrowth evaluation, histopathological examination and confocal laser microscopy imaging

February 2023 in “International Journal of Pharmaceutics”

A new version of minoxidil, a hair loss treatment, was made using nanotechnology. This version, called minoxidil cubosomes, works better and causes fewer skin reactions than the old version. It also penetrates and stays in the skin better, promoting hair regrowth. It's safe and could be a good alternative to current treatments.

Investigation of the Cutaneous Penetration Behavior of Dexamethasone Loaded to Nano-Sized Lipid Particles by EPR Spectroscopy, and Confocal Raman and Laser Scanning Microscopy

research Investigation of the cutaneous penetration behavior of dexamethasone loaded to nano-sized lipid particles by EPR spectroscopy, and confocal Raman and laser scanning microscopy

21 citations , December 2016 in “European journal of pharmaceutics and biopharmaceutics”

Nano-sized lipid particles increase dexamethasone's skin penetration and create a reservoir in the skin layers.

research Confocal Laser Scanning Microscopy: An Excellent Tool for Tracking Compounds in the Skin

5 citations , November 2005

Confocal Laser Scanning Microscopy is effective for tracking compounds in the skin.

research Confocal Laser Scanning Microscopy as a Tool for the Investigation of Skin Drug Delivery Systems and Diagnosis of Skin Disorders

4 citations , March 2013 in “InTech eBooks”

Confocal Laser Scanning Microscopy (CLSM) is a useful tool for studying how drugs interact with skin and diagnosing skin disorders, despite some limitations.

research Evaluation of Skin Penetration of Fluorescent Dissolved Formulations Using Confocal Laser Scanning Microscopy

2 citations , November 2025 in “Pharmaceutics”

Moderately lipophilic dyes penetrate skin deeply, while highly hydrophobic or lipophilic dyes stay on the surface.

research Development and Skin Penetration Pathway Evaluation Using Confocal Laser Scanning Microscopy of Microemulsions for Dermal Delivery Enhancement of Finasteride

1 citations , December 2022 in “Pharmaceutics”

Finasteride-loaded microemulsions can effectively enhance skin delivery for treating hair loss.

research Investigations on the penetration of hydrolyzed wheat proteins into human hair by confocal laser-scanning fluorescence microscopy

11 citations , January 2000 in “Journal of cosmetic science”

Hydrolyzed wheat proteins penetrate all hair types effectively.

Development of Topical Formulations Containing 20% Zinc Oxide Nanoparticles: Stability Assessment and Penetration Evaluation

research Development of Topical Formulations Containing 20% of Coated and Uncoated Zinc Oxide Nanoparticles: Stability Assessment and Penetration Evaluation by Reflectance Confocal Laser Microscopy

September 2023

The new skin cream with zinc oxide nanoparticles is stable, spreads well, and doesn't deeply penetrate the skin.

research Use of confocal microscopy for nanoparticle drug delivery through skin

57 citations , December 2012 in “Journal of Biomedical Optics”

Confocal microscopy is useful for studying how nanoparticles interact with skin.

Reflection Confocal Microscope Characteristics of Rosacea and Related Observations

research Reflection confocal microscope characteristics of rose acne and some thoughts caused by it

July 2022 in “Skin research and technology”

Skin CT can help diagnose rosacea by identifying specific skin features, but should be used with clinical signs to avoid misdiagnosis.

research Comparison of the efficacy and safety of a picosecond alexandrite laser and a Q-switched alexandrite laser for the treatment of freckles in Chinese patients

19 citations , August 2018 in “Journal of the American Academy of Dermatology”

Both lasers are equally effective and safe for treating freckles.

research Reactive keratin derivatives: A promising strategy for covalent binding to hair

20 citations , September 2018 in “Journal of colloid and interface science”

Modified keratin binds better to hair, especially bleached hair.

research Mechanistic study of decreased skin penetration using a combination of sonophoresis with sodium fluorescein-loaded PEGylated liposomes with D-limonene

2 citations , December 2015 in “DOAJ (DOAJ: Directory of Open Access Journals)”

Sonophoresis reduces skin absorption of sodium fluorescein in certain liposomes.

Lifting the Biofilm Lid on the Antibacterial and Antibiofilm Effects of Sodium Hypochlorite Against Staphylococcus Aureus in Atopic Dermatitis

research Lifting the biofilm lid on the antibacterial and antibiofilm effects of sodium hypochlorite against Staphylococcus aureus in atopic dermatitis

1 citations , August 2017 in “British Journal of Dermatology”

Sodium hypochlorite can effectively prevent and remove Staphylococcus aureus biofilms in atopic dermatitis at high enough concentrations.

research Montagna Symposium 2013—Light and Skin: How Light Sustains, Damages, Treats, Images and Modifies Skin Biology

1 citations , July 2014 in “The journal of investigative dermatology/Journal of investigative dermatology”

Light affects skin health, aging, and cancer risk, and new light-based treatments and imaging are promising for skin care.

research Follicular transport route – Research progress and future perspectives

211 citations , February 2009 in “European journal of pharmaceutics and biopharmaceutics”

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

research Polymeric Micelle Nanocarriers for the Cutaneous Delivery of Tacrolimus: A Targeted Approach for the Treatment of Psoriasis

159 citations , July 2014 in “Molecular pharmaceutics”

New micelle nanocarriers deliver Tacrolimus more effectively to skin layers for psoriasis treatment than the current Protopic ointment.

research Dendritic polyglycerol and N-isopropylacrylamide based thermoresponsive nanogels as smart carriers for controlled delivery of drugs through the hair follicle

62 citations , November 2016 in “Nanoscale”

Medium to larger nanogels effectively deliver drugs through hair follicles when heated.

Penetration and Distribution of Three Lipophilic Probes in Human Skin Focusing on the Hair Follicle

research Penetration and distribution of three lipophilic probes in vitro in human skin focusing on the hair follicle

54 citations , October 2002 in “Journal of controlled release”

Medium lipophilic substances penetrate skin best, and adding ethanol can increase delivery to hair follicles.

research Selective delivery of adapalene to the human hair follicle under finite dose conditions using polymeric micelle nanocarriers

50 citations , December 2017 in “Nanoscale”

Polymeric micelle nanocarriers deliver adapalene more effectively to hair follicles than commercial products.

research Effect of liposomal fluidity on skin permeation of sodium fluorescein entrapped in liposomes

21 citations , July 2015 in “International Journal of Nanomedicine”

Increased liposome fluidity boosts skin penetration of sodium fluorescein.

research Gradient-dependent release of the model drug TRITC-dextran from FITC-labeled BSA hydrogel nanocarriers in the hair follicles of porcine ear skin

18 citations , October 2016 in “European Journal of Pharmaceutics and Biopharmaceutics”

The drug was successfully released into hair follicles using nanocarriers.

Mechanistic Analysis of Human Skin Distribution and Follicular Targeting of Adapalene-Loaded Biodegradable Nanospheres With Insight Into Hydrogel Matrix Influence, In Vitro Skin Irritation, and In Vivo Tolerability

research Mechanistic Analysis of Human Skin Distribution and Follicular Targeting of Adapalene-Loaded Biodegradable Nanospheres With an Insight Into Hydrogel Matrix Influence, In Vitro Skin Irritation, and In Vivo Tolerability

17 citations , June 2017 in “Journal of pharmaceutical sciences”

Researchers developed a nanomedicine for acne treatment that delivers medication with less irritation and is non-irritating for oily skin.

research Determination of the pH Gradient in Hair Follicles of Human Volunteers Using pH-Sensitive Melamine Formaldehyde-Pyranine Nile Blue Microparticles

13 citations , September 2020 in “Sensors”

Hair follicles have a pH gradient, increasing towards the root.

research Targeted photosensitizer delivery: A prospective approach to vitiligo photochemotherapy

9 citations , May 2019 in “Vestnik dermatologii i venerologii”

The method could improve vitiligo treatment by effectively delivering therapy to hair follicles.

research Methodologies to Evaluate the Hair Follicle-Targeted Drug Delivery Provided by Nanoparticles

4 citations , July 2023 in “Pharmaceutics (Basel)”

Nanoparticle-based drug delivery to hair follicles is more effective when tested under conditions that match skin behavior.

The Impact of Particle Size of Nanostructured Lipid Carriers on Follicular Drug Delivery: A Comprehensive Analysis of Mouse and Human Hair Follicle Penetration

research The impact of particle size of nanostructured lipid carriers on follicular drug delivery: A comprehensive analysis of mouse and human hair follicle penetration

March 2024 in “Bioimpacts”

400 nm particles penetrate hair follicles best, but mouse models aren't fully reliable for human studies.

Skin Targeting of an Optimized Caffeine Nanostructured Lipid Carrier with Improved Efficiency Against Chemotherapy-Induced Alopecia

research SKIN TARGETING OF AN OPTIMIZED CAFFEINE NANOSTRUCTURED LIPID CARRIER WITH IMPROVED EFFICIENCY AGAINST CHEMOTHERAPY INDUCED ALOPECIA

July 2022 in “International Journal of Applied Pharmaceutics”

The optimized caffeine formula improved hair growth and penetrated all skin layers.

research Skin Targeting of An Optimized Caffeine Nanostructured Lipid Carrier With Improved Efficiency Against Chemotherapy Induced Alopecia

November 2021 in “Research Square (Research Square)”

The new caffeine cream works better for hair growth than existing products.