research Breaking the ‘rule-of-five’ to access bridged bicyclic heteroaromatic bioisosteres
A new method creates unique chemical structures that could improve drug discovery.
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720-750 / 1000+ results research Efficacy of low-level laser therapy in androgenetic alopecia – A randomized controlled trial
Low-level laser therapy is safe but not significantly better than minoxidil alone for hair growth.
research Faculty Opinions recommendation of Therapeutic implications of topical cetirizine 1% in treatment of male androgenetic alopecia: A case-controlled study.
research Novel Strategies for Androgenetic Alopecia Therapy: Integrating Multifunctional Plant Extracts with Nanotechnology for Advanced Cutaneous Drug Delivery
Combining plant extracts with nanotechnology may improve hair loss treatments.
research Alopecia Management Potential of Rosemary-Based Nanoemulgel Loaded with Metformin: Approach Combining Active Essential Oil and Repurposed Drug
Rosemary-based gel with metformin may effectively treat hair loss like minoxidil.
research Applications and Perspectives of Hydrogels in Veterinary Medicine
Hydrogels have great potential for improving wound care, drug delivery, and tissue engineering in veterinary medicine.
research Methotrexate in dermatology
Methotrexate is a key, cost-effective drug for skin conditions, but requires careful monitoring for side effects.
research Formulation of chloroaluminum phthalocyanine incorporated into PS-b-PAA diblock copolymer nanomicelles
The PS-b-PAA copolymer nanomicelles are effective for delivering a cancer treatment drug in photodynamic therapy.
research Levodopa-induced skin disorders in patients with Parkinson disease: a systematic literature review approach
Levodopa for Parkinson's disease might be linked to skin issues like melanoma, but it's unclear if the drug or the disease causes them.
research Efficacy of Cetirizine 1% Versus Minoxidil 5% Topical Solution in the Treatment of Male Alopecia: A Randomized, Single-blind Controlled Study
Cetirizine 1% helps hair growth in men with no major side effects, but minoxidil 5% works better.
research Issues in the Treatment of Epilepsy
Treating epilepsy is complex, requiring careful drug choice and patient adherence to manage seizures and side effects.
research Exhaustive analysis of scalp hair regression: subjective and objective perception from initial hair loss to severe miniaturisation and drug-induced regrowth
Hair loss reduces hair thickness and coverage, but drug treatments mainly revive dormant hairs rather than reverse thinning; patients often undervalue their hair loss severity.
research The effects of spinach-derived thylakoid supplementation in combination with calorie restriction on anthropometric parameters and metabolic profiles in obese women with polycystic ovary syndrome: a randomized, double-blind, placebo-controlled clinical trial
Spinach-derived thylakoid supplements plus a low-calorie diet helped obese women with polycystic ovary syndrome lose weight and improve their metabolism.
research Skin and Scalp Health Benefits of a Specific Botanical Extract Blend: Results from a Double-Blind Placebo-Controlled Study in Urban Outdoor Workers
A botanical extract blend improved skin and scalp health in women working outdoors.
research Valproate-Associated Transaminitis and Rhabdomyolysis
Valproic acid can cause muscle damage and liver issues, which improve after stopping the drug.
research Industry update: the latest developments in the field of therapeutic delivery, July 2018
New partnerships, clinical trials, and drug approvals marked progress in therapeutic delivery in July 2018.
research Antihelminthic Drugs
Antihelminthic drugs treat worm infections but face challenges like low treatment coverage and potential drug resistance, with various side effects reported for different drugs.
research Low-level Laser Therapy with Novel Array of Light Source and Individualized Program for Treatment of Androgenetic Alopecia: A 16-week, Randomized, Double-blind, Sham Device-controlled Study
The laser therapy device effectively increased hair growth in people with androgenetic alopecia.
research Comparison of single-spin to double-spin platelet-rich plasma centrifugation methods in the treatment of androgenic alopecia: a systematic review and meta-analysis of randomized controlled trials
Single-spin and double-spin PRP methods are equally effective for treating hair loss.
research A Randomized, Double‐Blind, Placebo‐Controlled Study to Evaluate the Safety and Efficacy of a Nutraceutical Supplement With Standardized Botanicals in Males With Thinning Hair
The supplement improved hair growth and quality in men with thinning hair and was safe to use.
research Cryotherapy versus fractional carbon dioxide laser in patchy alopecia areata: a self-controlled comparative study
Both cryotherapy and FCO2 laser are effective and safe for treating patchy alopecia areata.
research A randomized, double-blind, placebo controlled, and half-head study to evaluate the effects of platelet-rich plasma on androgenetic alopecia
PRP injections did not significantly improve hair growth in men with androgenetic alopecia.
research Growth Factor Cocktail Including Fibroblast Growth Factor 9 (Cellcurin) in the Treatment of Androgenetic Alopecia in Men and Women: A Randomized Controlled Trial
Cellcurin therapy with microneedling increases hair density and thickness in treating hair loss in men and women.
research Structural & functional studies of L-PGDS and SMPDL3A enzymes in lipid signaling family
L-PGDS has specific binding sites for its functions and could help in drug delivery system design.
research Lasers in Hair Growth and Hair Transplantation
Lasers are less favored for hair transplant surgery but show promise for hair growth in controlled trials.
research Latest developments in the field of stem cell research and regenerative medicine compiled from publicly available information and press releases from nonacademic institutions, 1–30 September 2016
In September 2016, there were major advancements and promising clinical trials in stem cell research and regenerative medicine.
research Efficacy of platelet-rich plasma in Asians with androgenetic alopecia: A randomized controlled trial
research Thiolated and PEGylated silica nanoparticle delivery to hair follicles
Using longer PEG chains helps nanoparticles penetrate hair follicles better, improving drug delivery for conditions like alopecia.
research Bio-macromolecules/modified-halloysite composite hydrogel used as multi-functional wound dressing
The new hydrogel is good for wound dressing because it absorbs water quickly, has high porosity, can release drugs, fights bacteria, and helps wounds heal with less scarring.
research Potential use of the Asteraceae family as a cure for diabetes: A review of ethnopharmacology to modern day drug and nutraceuticals developments
Asteraceae plants may help treat diabetes, but more research is needed.