November 2022 in “Journal of the Endocrine Society” The patient likely has Chrousos syndrome, a rare condition causing insensitivity to glucocorticoids, requiring high-dose dexamethasone treatment.
42 citations
,
November 2019 in “Frontiers in Endocrinology” The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.
February 2026 in “Brazilian Journal of Implantology and Health Sciences” Chronic stress and high cortisol levels can cause hair loss by disrupting hair growth.
October 2025 in “Journal of the Endocrine Society” Surgery improved symptoms and normalized hormone levels in a woman with an adrenal tumor.
11 citations
,
April 2023 in “Skin Health and Disease” Psychological stress can worsen skin conditions like psoriasis and acne.
July 2017 in “Contemporary Endocrinology” The document concludes that patient outcomes for Congenital Adrenal Hyperplasia are often not ideal because of poor management and a need for better diagnosis and treatment methods.
December 2023 in “Journal of the Endocrine Society” Blocking glucocorticoid receptors improves glucose metabolism in a PCOS mouse model.
119 citations
,
August 2010 in “Journal of Investigative Dermatology” Increased 11β-HSD1 activity in skin may contribute to aging and could be targeted to reduce aging effects.
1 citations
,
October 2005 in “Experimental and Clinical Endocrinology & Diabetes” Allopregnanolone and opioids together reduce stress hormone responses during pregnancy.
October 2023 in “Journal of the Endocrine Society” A woman's cyclic Cushing syndrome was caused by a tumor in her adrenal gland that produced ACTH.
35 citations
,
April 2021 in “Current Biology” January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” The study aims to see if maternal hair cortisol levels during pregnancy relate to adverse childhood experiences.
A woman's Cushing's syndrome caused by adrenal cancer improved after surgery.
237 citations
,
September 2018 in “Clinical Biochemistry” Hair cortisol analysis can help diagnose stress-related conditions but needs more refinement for widespread use.
April 2011 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Hair cortisol is a reliable long-term stress marker during pregnancy.
1 citations
,
October 2023 in “Journal of the Endocrine Society” Testosterone treatment may affect heart response to stress in transgender men.
80 citations
,
November 2017 in “New Phytologist” Roots adapt to uneven environments by changing growth and gene expression.
July 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Seeing trauma causes fear in mice by lowering their natural fear-reducing hormones.
11 citations
,
February 2005 in “Clinical pharmacology and therapeutics/Clinical pharmacology & therapeutics” Hair cortisol could be a marker for chronic stress in pregnancy, but depression affects cortisol levels differently.
5 citations
,
January 2012 in “Dermatology” Adapted classification better assesses male pattern hair loss and its link to heart disease.
June 2025 in “Molecular Genetics & Genomic Medicine” Severe genetic variants in children with a specific adrenal condition match predicted symptoms well, but milder variants do not.
19 citations
,
September 2010 in “The American journal of pathology” High glucocorticoids cause pancreatic malfunction and malabsorption, reversible with enzyme supplements.
November 2009 in “Journal of Pediatric Nursing” Nonclassic congenital adrenal hyperplasia is a common genetic disorder that can cause a range of symptoms and requires personalized treatment.
July 2025 in “International Journal of Dermatology Venereology and Leprosy Sciences” Higher stress levels may worsen alopecia areata, suggesting stress management is important for treatment.
10 citations
,
September 2019 in “Frontiers in Veterinary Science” Older steers have higher hair cortisol levels than younger steers.
54 citations
,
May 2015 in “Endocrinology” Manipulating 5α-reductase type 2 can affect liver fat production and glucocorticoid effects.
May 2024 in “International journal of medicine and psychology.” Active coping improves stress resistance in law enforcement officers.
2 citations
,
April 2017 in “PubMed” Fat cells near hair follicles may affect hair growth and could help treat baldness.
February 2024 in “Psychoneuroendocrinology” Higher prenatal anxiety is linked to lower cortisol levels in newborns' hair.
50 citations
,
November 2020 in “Physiology & behavior” People with depression often have higher hair cortisol levels, while those with PTSD tend to have lower levels, but more research is needed to understand this fully.