July 2025 in “The FASEB Journal” Human amniotic stem cell exosomes may effectively treat hair loss by promoting hair regrowth.
79 citations
,
December 2013 in “Journal of Investigative Dermatology Symposium Proceedings” Alopecia areata may be treated by restoring hair follicle immune privilege and adjusting immune responses.
2 citations
,
May 2024 in “Immunity” Stem cells help control the immune response to improve wound healing.
1 citations
,
April 2023 in “Frontiers in Immunology” New treatments for hair loss from alopecia areata may include targeting immune cells, using stem cells, balancing gut bacteria, applying fatty acids, and using JAK inhibitors.
50 citations
,
December 2005 in “European Journal of Immunology” RXRα is crucial for proper immune response and links diet to immune function.
16 citations
,
April 2024 in “Proceedings of the National Academy of Sciences” HDAC4 and HDAC7 are crucial for Th17 cell development and could be targeted to treat inflammatory diseases.
8 citations
,
December 2013 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Mouse models help understand alopecia areata and find treatments.
114 citations
,
August 2002 in “Journal of Investigative Dermatology” Alopecia areata is caused by an immune response, and targeting immune cells might help treat it.
101 citations
,
July 1998 in “Journal of Investigative Dermatology” UVB exposure in human skin causes macrophages to produce more IL-10 and less IL-12, leading to immunosuppression.
46 citations
,
November 2022 in “The Journal of Dermatology” Bullous pemphigoid is influenced by genetic factors, immune cell dysfunction, aging, and triggers, with treatment often improving symptoms.
31 citations
,
January 2009 in “Autoimmunity Reviews” Damage to hair follicle stem cells causes permanent hair loss and scarring in cutaneous lupus erythematosus.
29 citations
,
November 2011 in “Cell stress & chaperones” Quercetin effectively treated and prevented hair loss in mice.
May 2023 in “Frontiers in Immunology” Treg cell-based therapies might help treat hair loss from alopecia areata, but more research is needed to confirm safety and effectiveness.
286 citations
,
August 2007 in “Journal of Clinical Investigation” Alopecia areata is an autoimmune disease where T cells attack hair follicles.
91 citations
,
May 2023 in “Journal of Cutaneous Medicine and Surgery” Alopecia Areata affects 2% globally, with treatments like essential oils, garlic, and JAK inhibitors showing promise, but more research is needed.
31 citations
,
August 2015 in “Stem Cells Translational Medicine” Human skin can provide stem cells for tissue repair and regeneration, but there are challenges in obtaining and growing these cells safely.
26 citations
,
February 2021 in “FEBS Journal” Targeting regulatory T cells may help treat age-related diseases.
21 citations
,
January 2022 in “Biomaterials Science” RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.
7 citations
,
January 2020 in “Frontiers in Pharmacology” Jagged1 and Epidermal Growth Factor together significantly increased hair growth in mice with androgen-suppressed hair.
7 citations
,
July 2013 in “InTech eBooks” Oral lichen planus is a chronic disease causing mouth discomfort and sometimes needs immunosuppressive treatment.
5 citations
,
March 2025 in “Pediatric Dermatology” Alopecia areata in children is caused by the immune system attacking hair follicles due to genetic factors.
1 citations
,
January 2025 in “Genes & Diseases” Understanding T cells and signaling pathways can lead to better treatments for hair loss.
February 2026 in “Stem Cell Research & Therapy” Stem cell therapies show promise for hair regrowth in alopecia areata but need more research for safety and effectiveness.
January 2026 in “Immunological Reviews” Females generally have stronger immune responses than males due to the X chromosome.
September 2025 in “Frontiers in Immunology” Atopic dermatitis and alopecia areata share immune and genetic factors, and targeted therapies may help both.
31 citations
,
July 2023 in “Nutrients” Vitamin D may help reduce thyroid antibodies and improve thyroid function in Hashimoto's Thyroiditis.
16 citations
,
June 2025 in “Journal of Composites Science” Chitosan–hydroxyapatite biocomposites are promising for tissue engineering due to their safety and ability to support healing.
January 2026 in “Nutrients” Low vitamin D may increase autoimmune thyroid disease risk, but its treatment effects are unclear.
Stress can cause hair loss and trigger autoimmunity by damaging hair follicle cells.
November 2025 in “Stem Cell Research & Therapy” Human hair follicle cells can help regenerate hair and reduce inflammation, aiding in hair loss treatment.