research Advances in Innovative Surgical Implant Manufacturing for Hernia Repair and Soft Tissue Reconstruction
Coating surgical meshes with PRP may improve hernia repair outcomes.
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240-270 / 1000+ resultsresearch Genome-wide association study in alopecia areata implicates both innate and adaptive immunity
Alopecia areata involves both innate and adaptive immunity, with specific genes linked to the disease.
research Homeostatic Control of Sebaceous Glands by Innate Lymphoid Cells Regulates Commensal Bacteria Equilibrium
Innate lymphoid cells help control skin bacteria by regulating sebaceous glands.
research A bibliometric analysis of T cell and atherosclerosis
T cells and inflammation are crucial in atherosclerosis, with anti-inflammatory treatments showing promise.
research The Immunological Impact of IL-1 Family Cytokines on the Epidermal Barrier
IL-1 family cytokines are crucial for skin defense and healing, but their imbalance can cause skin diseases.
research Increased CRHR1 expression on monocytes from patients with AA enables a pro‐inflammatory response to corticotrophin‐releasing hormone
Higher CRHR1 levels in AA patients lead to increased inflammation.
research Clinical and Genetic Aspects of Alopecia Areata: A Cutting Edge Review
Hair loss from Alopecia Areata is caused by both genes and environment, with several treatments available but challenges in cost and relapse remain.
research Summary of the Preceding Three Alopecia Areata Research Summits: What’s Past Is Prologue
New treatments and strategies are needed for Alopecia Areata, focusing on immune response and better trial designs.
research Tertiary Lymphoid Organs at the Center Stage of Skin's Humoral Immunity
The skin can independently form immune responses through special structures, offering new ways to treat skin diseases.
research Associations between ionomic profile and metabolic abnormalities in a murine model of sodium sulfide induced alopecia areata
Targeting gut microbiome and metabolome may help treat autoimmune skin diseases like alopecia areata.
research CGF therapy: bridging androgenetic alopecia observations to psoriasis treatment via IL-17 pathway
CGF therapy may effectively treat psoriasis by reducing inflammation.
research Activator Protein-1 Activity Regulates Epithelial Tumor Cell Identity
AP-1 controls tumor cell type by affecting key signaling pathways.
research 054 Deep Analysis of CD4+ Trm Cells in Normal and Atopic Dermatitis Human Skin
Certain immune cells in atopic dermatitis skin could be targeted for treatment.
research Systemic Autoimmune Diseases
The document concludes that systemic autoimmune diseases are complex, incurable, and require ongoing treatment and research.
research Cell adhesion molecules in inflammatory and neoplastic skin diseases
Cell adhesion molecules are important in the development of certain skin diseases.
research CD200-Mediated Regulation of Skin Immunity
research Signaling modality within gp130 receptor enhances tissue regeneration
The gp130 receptor helps in tissue regeneration and disease progression, and manipulating it could improve healing and prevent disease.
research SOCS1 and SOCS3 as key checkpoint molecules in the immune responses associated to skin inflammation and malignant transformation
SOCS1 and SOCS3 help control skin inflammation and are important for developing treatments for skin diseases.
research LB1031 Immune Cell-Mediated Amplification of Stem Cell Activation in Hairy Melanocytic Nevus via Osteopontin-CD44 Axis
Immune cells boost stem cell activity in hairy moles, causing more hair growth.
research Rethinking regeneration: empowerment of stem cells by inflammation
Inflammation helps stem cells repair tissue by directing their behavior.
research Stem cells supporting other stem cells
Stem cells can help other stem cells by producing supportive factors.
research Editors' Picks
Collagen VII helps skin heal and stay strong, sirolimus may lower skin cancer risk in kidney transplant patients, high-molecular-mass hyaluronan helps naked mole rats resist cancer, dermal γδ T cells aid in hair growth in rodents, and overexpression of IL-33 in mouse skin causes itchiness, offering a model for studying allergic inflammation treatments.
research Internal peacekeepers and external mediators: A new model of peripheral immune tolerance involving regulatory T cells and mesenchymal stem cells
Regulatory T cells and mesenchymal stem cells work together to prevent immune system overreactions and tissue damage.
research Proinflammatory cytokines regulate epidermal stem cells in wound epithelialization
Certain immune system proteins are important for skin healing but can cause problems if there are too many of them.
research Molecular mediators involved in skin healing: a narrative review
Understanding biological mediators in skin healing can improve treatments for skin wounds.
research Editors' Picks
Activin increases skin tumor formation, skin Tregs help hair growth, lymph-node removal doesn't improve melanoma survival, cells can revert to stem cells in wound healing, and skin bacteria produce peptides that may treat infections.
research Cytokine Engineering Approaches for Regenerative Medicine
Engineered cytokines show promise for improving tissue healing and safety in regenerative medicine.
research c-Kit - The Novel Receptor: Physiological Roles, Downstream Signaling and Implications in Cancer
c-Kit is important for heart regeneration and cancer development.
research The pivotal role of PDGF and its receptor isoforms in adipose-derived stem cells.
PDGF and its receptors are crucial for stem cell growth and function.
research Biomimetic Cell Membrane‐Coated Scaffolds for Enhanced Tissue Regeneration
Biomimetic cell membrane-coated scaffolds significantly enhance tissue regeneration by mimicking natural cellular environments.