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The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

CLEC10A and interleukin-42 can help identify PCOS patients' response to Metformin treatment.

Epidermal growth factor reduces hair growth, but cortisol does not.

Women with PCOS often have hirsutism and skin changes, which indicate a need for metabolic health checks.

Cronkhite-Canada syndrome is rare, has a poor prognosis, and requires early diagnosis and ongoing treatment.

Targeting the p300/AR axis may help treat polycystic ovary syndrome.

The cause of atypical Cushing's syndrome in dogs, possibly linked to sex hormones, is not yet proven.

Activating cAMP and ATP improves hair growth and strength.

A mycobacterial protein shares a similar region with a human skin protein, possibly affecting skin diseases.

CHIR99021 helps create human skin with hair follicles, offering hope for hair loss treatments.

CRH causes hair loss by reducing autophagy and increasing cell death in hair cells.

The B2C promoter works in sheep cells but not in mouse embryos.

Early detection of Cushing's syndrome during pregnancy is crucial to prevent severe complications.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Accurate diagnosis of PCOS requires comprehensive androgen measurement.

Clascoterone cream could be used for other skin conditions affected by hormones.

Most patients experienced hirsutism again after stopping hormone treatment, indicating long-term treatment is needed to maintain results.

Low oxygen levels improve the function of hair and skin cells when they are in direct contact.

Probiotics and synbiotics may help with PCOS symptoms, but more research is needed.

Endocrine therapy helps with reproductive and metabolic issues in women with PCOS.

Cyclosporin extends hair growth in mice, but high-dose corticosteroids block this effect.

Testosterone undecanoate increases lean mass and causes various physical changes in female-to-male transsexuals.

Women with congenital adrenal hyperplasia (CAH) have more sexual function issues than those with polycystic ovary syndrome (PCOS), but physical activity can improve sexual functioning in all women.

Amenorrhea is relatively rare and initial testing should check FSH, TSH, and prolactin levels.

Overexpressing the Tβ4 gene in goats can increase cashmere production.

The patient had a severe allergic reaction to gold treatment.

The therapies improved ejaculation disorders and sexual function in middle-aged men.

Microneedle arrays deliver botulinum toxin effectively for sweat suppression, similar to injections.

Cyproterone acetate is used for topical treatment of diseases dependent on male hormones.