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Azathioprine caused side effects in over half of the Korean pediatric inflammatory bowel disease patients, requiring close monitoring.

Androgen-modulating drugs do not significantly change the heat sensitivity of prostate cancer cells.

Different keratins have unique expression patterns in mouse skin cells.

Skin organoids can model tuberculosis infection and help test treatments.

Ixekizumab is safe for long-term use with low rates of major heart-related events.

BI 2536 had limited effectiveness against several advanced cancers and caused significant side effects.

MC-1R in skin cells may influence inflammation and collagen production.

Mutants of CYP154C2 enzyme significantly improved steroid conversion efficiency.

Social media can help compare the effectiveness and safety of new arthritis medications.

Certain proteins can either protect against or increase the risk of hypertrophic scars.

Nociplastic pain is a complex, heritable trait with genetic links to chronic and neuropathic pain.

Oriental herbal medicine with moxibustion may improve pregnancy rates and other symptoms in PCOS, but more high-quality research is needed.

RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.

AP-1 and TGFß work together to drive resistance in basal cell carcinoma, suggesting new treatment options.

Mouse skin cancer progression involves a unique group of cells marked by ABCG2 and MTS24.

The conclusion is that the cornea has two types of stem cells, with Lrig1+ cells being key for renewal in aging corneas, independent of CD44.

Vaccines and targeting TrxR variants can help prevent cancer and reduce metastasis.

NADPH oxidase 4 is key for stem cell activity and growth under low oxygen.

Secukinumab reduces immune activity in hidradenitis suppurativa skin.

Targeting NETs may help reduce fibrosis in Crohn's disease.

Mast cells and CD8 T cells interact closely in skin diseases, affecting each other's behavior and contributing to conditions like psoriasis and eczema.

The enzyme pyruvate kinase M2 helps hair regrowth and could be a potential treatment for hair loss.

Certain MC4R gene variants are linked to higher BMI in obese women with PCOS but do not cause PCOS.

Androgen receptors help prostate cancer cells grow and resist drugs.

FOXO1 is important for wound healing, but its dysfunction in diabetes can slow the healing process.

The research suggests that a specific skin gene can be controlled by signals within and between cells and is wrongly activated in certain skin diseases.

ROR2 is essential for hair follicle stem cell renewal and maintenance.