research Discovery of a novel hybrid from finasteride and epristeride as 5α-reductase inhibitor
New hybrid compound found to effectively prevent hair loss.
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research Stereocontrolled synthesis of all eight stereoisomers of the putative anti-androgen cyoctol
Scientists made all eight versions of a compound called cyoctol, but found it's not an anti-androgen and it fully breaks down in the skin.
research Wnt signaling activation: targets and therapeutic opportunities for stem cell therapy and regenerative medicine
Wnt activation shows promise for regenerative medicine but requires selective targeting to minimize risks like cancer.
research Pharmacological Options for Treatment of Hyperandrogenic Disorders
Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.
research Dyeing of Chitin Nanofibers With Reactive Dyes and Preparation of Their Sheets and Fiber Reinforced Materials
Dyed chitin nanofibers are strong, colorful, and water-resistant, enhancing resin strength and color.
research Hair growth at a solid-liquid interface as a protein crystal without cell division
Hair grows like a crystal at a solid-liquid interface without cell division.
research Electron microscopic and autoradiographic study of S35-L-cystine incorporation in mouse hair follicles
Mice hair follicles take in the amino acid cystine.
research Chemical Fingerprint and Quantitative Analysis for the Quality Evaluation of Platycladi cacumen by Ultra-performance Liquid Chromatography Coupled with Hierarchical Cluster Analysis
The new method is rapid, sensitive, and accurate for evaluating the quality of the medicinal herb Platycladi cacumen.
research (Un)targeted Scanning of Locks of Hair for Drugs of Abuse by Direct Analysis in Real Time–High-Resolution Mass Spectrometry
A new method can quickly and accurately detect drugs in hair.
research Wool fiber curvature is correlated with abundance of K38 and specific keratin‐associated proteins
Wool fiber curliness is linked to the presence of certain proteins and K38.
research A chemist's view of the analysis of human hair for trace elements
Analyzing trace elements in human hair is complex and needs a standardized method.
research A new staining method for visualization of keratin filaments in hair fibre cross sections.
A new method effectively visualizes keratin in hair without harsh chemicals.
![Benzo[c]quinolizin-3-ones Theoretical Investigation: SAR Analysis and Application to Untested Compounds](/images/research/6712367a-949f-47c7-a756-2bfe6316fc69/small/15331.jpg)
research Benzo[c]quinolizin-3-ones Theoretical Investigation: SAR Analysis and Application to Nontested Compounds
The research found a link between certain molecular features and the biological activity of BC3, which can help identify or create new active compounds.
research Reimagining Hair Science: A New Approach to Classify Curly Hair Phenotypes via New Quantitative Geometrical & Structural Mechanical Parameters
New methods to classify curly hair types were developed based on shape and strength.
research Discovery and Optimization of Novel Pyridines as Highly Potent and Selective Glycogen Synthase Kinase 3 Inhibitors
New pyridine compounds effectively inhibit GSK3, a diabetes treatment target.
research DRUG POLYMORPHISM IDENTIFICATION USING FOURIER TRANSFORM-RAMAN SPECTROSCOPY: A COMPARATIVE STUDY OF LAMIVUDINE AND FINASTERIDE DRUGS
FT-Raman spectroscopy is effective for identifying drug polymorphs, ensuring quality and stability.
research A Study of Aggregation Structures and Tensile Properties of Hair Fibers
research Investigating the internal structure of sheep wool hair fibre using new microscopic techniques
Curly wool has more orthocortex than straight wool.
research The location of the thioglycolic acid molecules in intrafibrillar unordered areas of the human hair keratin structure
Thioglycolic acid mainly affects the unordered areas in hair structure.
research Proteomic tools for the investigation of human hair structural proteins and evidence of weakness sites on hair keratin coil segments
Hair proteins have weak spots in their α-helical segments.
research Analyzing the laser-light reflection from human hair fibers. I. Light components underlying the goniophotometric curves and fiber cuticle angles.
The research found a way to measure hair surface changes by analyzing how light reflects off of it, and determined hair cuticle angles vary by hair length and color.
research Three‐dimensional imaging and analysis of the surface of hair fibres using scanning electron microscopy
The new 3D imaging method accurately measures hair surface details quickly.
research Secondary structure estimation and properties analysis of stretched Asian and Caucasian hair
Stretching damages Caucasian hair's structure more easily than Asian hair.
research 944 Non-coding double stranded RNA induces retinoic acid synthesis and retinoid signaling to control regeneration
Non-coding RNA boosts retinoic acid production and signaling, aiding regeneration.
research Improved two‐dimensional electrophoretic mapping of Japanese human hair proteins; application to curved and straight Japanese human hairs; and protein identification by MALDI MS and MS/MS quadrupole time‐of‐flight mass spectrometry
The study found that minor protein differences between curved and straight Japanese hair are unlikely to significantly affect hair structure.
research Three strands ironed closely together
A new method was developed to create complex molecular knots using iron ions.
research Mechanical anisotropy of hair affected by genetic diseases highlights structural information related to differential crosslinking in keratins
research Monitoring spatially resolved trace elements in polar bear hair using single spot laser ablation ICP-MS
Laser ablation ICP-MS is effective for tracking trace elements in polar bear hair over time.
research A reciprocal lattice approach to assessing the luster of hair fibers, based on scattering by periodically deformed cylinders
A new method helps understand hair shine and various products improve hair care.
research Hard alpha-keratin degradation inside a tissue under high flux X-ray synchrotron micro-beam: A multi-scale time-resolved study
High flux X-ray beams quickly damage the structure of human hair.